LOCUS       HR180-LGR5-CreER               10707 bp ds-DNA     circular     04-Jun-2019
DEFINITION  .
ACCESSION   .
VERSION     .
SOURCE      Human
 ORGANISM   
REFERENCE   1  (bases 402 to 8446)
 AUTHORS    Shimokawa M, Ohta Y, Nishikori S, Matano M, Takano A, Fujii M, Date S, Sugimoto S, Kanai T & Sato T
 TITLE      Visualization and targeting of LGR5+ human colon cancer stem cells
 JOURNAL    Nature. 2017 May 11;545(7653):187-192. doi: 10.1038/nature22081. Epub 2017 Mar 29.
 PUBMED     28355176 
FEATURES             Location/Qualifiers
     gene            402..1419
                     /label=LGR5 5' homologous arm
     misc_feature    1457..2103
                     /label=IRES
     CDS             2110..4095
                     /label=CreERT2
     polyA_signal    4102..4249
                     /label=SV40 polyA
     misc_feature    4276..4309
                     /label=>LoxP(1)
                     /ApEinfo_label=>LoxP
                     /ApEinfo_fwdcolor=#8080c0
                     /ApEinfo_revcolor=green
                     /ApEinfo_graphicformat=arrow_data {{0 1 2 0 0 -1} {} 0}
                     width 5 offset 0
     enhancer        4373..4604
                     /label=core insul(1)
                     /ApEinfo_label=core insul
                     /ApEinfo_fwdcolor=#d7cccc
                     /ApEinfo_revcolor=green
                     /ApEinfo_graphicformat=arrow_data {{0 1 2 0 0 -1} {} 0}
                     width 5 offset 0
     misc_feature    4631..5176
                     /label=EF1 promoter
                     /ApEinfo_fwdcolor=cyan
                     /ApEinfo_revcolor=green
                     /ApEinfo_graphicformat=arrow_data {{0 1 2 0 0 -1} {} 0}
                     width 5 offset 0
     misc_feature    5189..5866
                     /label=mRuby
                     /ApEinfo_fwdcolor=#ff0000
                     /ApEinfo_revcolor=green
                     /ApEinfo_graphicformat=arrow_data {{0 1 2 0 0 -1} {} 0}
                     width 5 offset 0
     misc_feature    5867..5920
                     /label=T2A
                     /ApEinfo_fwdcolor=#ff80ff
                     /ApEinfo_revcolor=green
                     /ApEinfo_graphicformat=arrow_data {{0 1 2 0 0 -1} {} 0}
                     width 5 offset 0
     misc_feature    5921..6520
                     /label=Puro
                     /ApEinfo_fwdcolor=#ff00ff
                     /ApEinfo_revcolor=green
                     /ApEinfo_graphicformat=arrow_data {{0 1 2 0 0 -1} {} 0}
                     width 5 offset 0
     misc_feature    6644..6774
                     /label=SV40 pA
                     /ApEinfo_fwdcolor=cyan
                     /ApEinfo_revcolor=green
                     /ApEinfo_graphicformat=arrow_data {{0 1 2 0 0 -1} {} 0}
                     width 5 offset 0
     enhancer        complement(7022..7252)
                     /label=core insul
                     /ApEinfo_fwdcolor=#d8cac8
                     /ApEinfo_revcolor=#d8c8c8
                     /ApEinfo_graphicformat=arrow_data {{0 1 2 0 0 -1} {} 0}
                     width 5 offset 0
     misc_feature    7265..7298
                     /label=>LoxP
                     /ApEinfo_fwdcolor=#8080c0
                     /ApEinfo_revcolor=green
                     /ApEinfo_graphicformat=arrow_data {{0 1 2 0 0 -1} {} 0}
                     width 5 offset 0
     misc_feature    7328..8473
                     /label=MCS2
                     /ApEinfo_fwdcolor=#ff00ff
                     /ApEinfo_revcolor=green
                     /ApEinfo_graphicformat=arrow_data {{0 1 2 0 0 -1} {} 0}
                     width 5 offset 0
     gene            7341..8446
                     /label=LGR5 3' homologous arm
     misc_feature    complement(8873..9487)
                     /label=Rep (pMB1)
                     /ApEinfo_fwdcolor=#00ff80
                     /ApEinfo_revcolor=green
                     /ApEinfo_graphicformat=arrow_data {{0 1 2 0 0 -1} {} 0}
                     width 5 offset 0
     misc_feature    complement(9647..10507)
                     /label=Amp
                     /ApEinfo_fwdcolor=#c0c0c0
                     /ApEinfo_revcolor=green
                     /ApEinfo_graphicformat=arrow_data {{0 1 2 0 0 -1} {} 0}
                     width 5 offset 0
BASE COUNT     2600 a   2760 c   2688 g   2659 t
ORIGIN
        1 TCGCGCGTTT CGGTGATGAC GGTGAAAACC TCTGACACAT GCAGCTCCCG GAGACGGTCA
       61 CAGCTTGTCT GTAAGCGGAT GCCGGGAGCA GACAAGCCCG TCAGGGCGCG TCAGCGGGTG
      121 TTGGCGGGTG TCGGGGCTGG CTTAACTATG CGGCATCAGA GCAGATTGTA CTGAGAGTGC
      181 ACCATATGCG GTGTGAAATA CCGCACAGAT GCGTAAGGAG AAAATACCGC ATCAGGCGCC
      241 ATTCGCCATT CAGGCTGCGC AACTGTTGGG AAGGGCGATC GGTGCGGGCC TCTTCGCTAT
      301 TACGCCAGCT GGCGAAAGGG GGATGTGCTG CAAGGCGATT AAGTTGGGTA ACGCCAGGGT
      361 TTTCCCAGTC ACGACGTTGT AAAACGACGG CCAGTGAATT CTCTGGCACT TACTTGTAAT
      421 GCTTTGGTGA CTTCAACAGT TTTCAGATCC CCTCTGTACA TTTCCCCCAT TAAACTGTTA
      481 ATTGGGGTCA TCGCAGCAGT GAACATGCTC ACGGGAGTCT CCAGTGCCGT GCTGGCTGGT
      541 GTGGATGCGT TCACTTTTGG CAGCTTTGCA CGACATGGTG CCTGGTGGGA GAATGGGGTT
      601 GGTTGCCATG TCATTGGTTT TTTGTCCATT TTTGCTTCAG AATCATCTGT TTTCCTGCTT
      661 ACTCTGGCAG CCCTGGAGCG TGGGTTCTCT GTGAAATATT CTGCAAAATT TGAAACGAAA
      721 GCTCCATTTT CTAGCCTGAA AGTAATCATT TTGCTCTGTG CCCTGCTGGC CTTGACCATG
      781 GCCGCAGTTC CCCTGCTGGG TGGCAGCAAG TATGGCGCCT CCCCTCTCTG CCTGCCTTTG
      841 CCTTTTGGGG AGCCCAGCAC CATGGGCTAC ATGGTCGCTC TCATCTTGCT CAATTCCCTT
      901 TGCTTCCTCA TGATGACCAT TGCCTACACC AAGCTCTACT GCAATTTGGA CAAGGGAGAC
      961 CTGGAGAATA TTTGGGACTG CTCTATGGTA AAACACATTG CCCTGTTGCT CTTCACCAAC
     1021 TGCATCCTAA ACTGCCCTGT GGCTTTCTTG TCCTTCTCCT CTTTAATAAA CCTTACATTT
     1081 ATCAGTCCTG AAGTAATTAA GTTTATCCTT CTGGTGGTAG TCCCACTTCC TGCATGTCTC
     1141 AATCCCCTTC TCTACATCTT GTTCAATCCT CACTTTAAGG AGGATCTGGT GAGCCTGAGA
     1201 AAGCAAACCT ACGTCTGGAC AAGATCAAAA CACCCAAGCT TGATGTCAAT TAACTCTGAT
     1261 GATGTCGAAA AACAGTCCTG TGACTCAACT CAAGCCTTGG TAACCTTTAC CAGCTCCAGC
     1321 ATCACTTATG ACCTGCCTCC CAGTTCCGTG CCATCACCAG CTTATCCAGT GACTGAGAGC
     1381 TGCCATCTTT CCTCTGTGGC ATTTGTCCCA TGTCTCTAAG AATTCGAGCT CGGTACCTCG
     1441 CGAATGCATC AGATCTGAGC TCGGTACCTC GCGAATGCAT CAGATCTGAT CCTCGAGGGC
     1501 CGGCGCGCCG CGGCCGCTAC GTAAATTCCG CCCCTCTCCC TAACGTTACT GGCCGAAGCC
     1561 GCTTGGAATA AGGCCGGTGT GCGTTTGTCT ATATGTTATT TTCCACCATA TTGCCGTCTT
     1621 TTGGCAATGT GAGGGCCCGG AAACCTGGCC CTGTCTTCTT GACGAGCATT CCTAGGGGTC
     1681 TTTCCCCTCT CGCCAAAGGA ATGCAAGGTC TGTTGAATGT CGTGAAGGAA GCAGTTCCTC
     1741 TGGAAGCTTC TTGAAGACAA ACAACGTCTG TAGCGACCCT TTGCAGGCAG CGGAACCCCC
     1801 CACCTGGCGA CAGGTGCCTC TGCGGCCAAA AGCCACGTGT ATAAGATACA CCTGCAAAGG
     1861 CGGCACAACC CCAGTGCCAC GTTGTGAGTT GGATAGTTGT GGAAAGAGTC AAATGGCTCT
     1921 CCTCAAGCGT ATTCAACAAG GGGCTGAAGG ATGCCCAGAA GGTACCCCAT TGTATGGGAT
     1981 CTGATCTGGG GCCTCGGTGC ACATGCTTTA CATGTGTTTA GTCGAGGTTA AAAAAACGTC
     2041 TAGGCCCCCC GAACCACGGG GACGTGGTTT TCCTTTGAAA AACACGATGA TAATATGGCC
     2101 ACAGATATCa ccATGTCCAA TTTACTGACC GTACACCAAA ATTTGCCTGC ATTACCGGTC
     2161 GATGCAACGA GTGATGAGGT TCGCAAGAAC CTGATGGACA TGTTCAGGGA TCGCCAGGCG
     2221 TTTTCTGAGC ATACCTGGAA AATGCTTCTG TCCGTTTGCC GGTCGTGGGC GGCATGGTGC
     2281 AAGTTGAATA ACCGGAAATG GTTTCCCGCA GAACCTGAAG ATGTTCGCGA TTATCTTCTA
     2341 TATCTTCAGG CGCGCGGTCT GGCAGTAAAA ACTATCCAGC AACATTTGGG CCAGCTAAAC
     2401 ATGCTTCATC GTCGGTCCGG GCTGCCACGA CCAAGTGACA GCAATGCTGT TTCACTGGTT
     2461 ATGCGGCGGA TCCGAAAAGA AAACGTTGAT GCCGGTGAAC GTGCAAAACA GGCTCTAGCG
     2521 TTCGAACGCA CTGATTTCGA CCAGGTTCGT TCACTCATGG AAAATAGCGA TCGCTGCCAG
     2581 GATATACGTA ATCTGGCATT TCTGGGGATT GCTTATAACA CCCTGTTACG TATAGCCGAA
     2641 ATTGCCAGGA TCAGGGTTAA AGATATCTCA CGTACTGACG GTGGGAGAAT GTTAATCCAT
     2701 ATTGGCAGAA CGAAAACGCT GGTTAGCACC GCAGGTGTAG AGAAGGCACT TAGCCTGGGG
     2761 GTAACTAAAC TGGTCGAGCG ATGGATTTCC GTCTCTGGTG TAGCTGATGA TCCGAATAAC
     2821 TACCTGTTTT GCCGGGTCAG AAAAAATGGT GTTGCCGCGC CATCTGCCAC CAGCCAGCTA
     2881 TCAACTCGCG CCCTGGAAGG GATTTTTGAA GCAACTCATC GATTGATTTA CGGCGCTAAG
     2941 GATGACTCTG GTCAGAGATA CCTGGCCTGG TCTGGACACA GTGCCCGTGT CGGAGCCGCG
     3001 CGAGATATGG CCCGCGCTGG AGTTTCAATA CCGGAGATCA TGCAAGCTGG TGGCTGGACC
     3061 AATGTAAATA TTGTCATGAA CTATATCCGT AACCTGGATA GTGAAACAGG GGCAATGGTG
     3121 CGCCTGCTGG AAGATGGCGA TCTCGAGCCA TCTGCTGGAG ACATGAGAGC TGCCAACCTT
     3181 TGGCCAAGCC CGCTCATGAT CAAACGCTCT AAGAAGAACA GCCTGGCCTT GTCCCTGACG
     3241 GCCGACCAGA TGGTCAGTGC CTTGTTGGAT GCTGAGCCCC CCATACTCTA TTCCGAGTAT
     3301 GATCCTACCA GACCCTTCAG TGAAGCTTCG ATGATGGGCT TACTGACCAA CCTGGCAGAC
     3361 AGGGAGCTGG TTCACATGAT CAACTGGGCG AAGAGGGTGC CAGGCTTTGT GGATTTGACC
     3421 CTCCATGATC AGGTCCACCT TCTAGAATGT GCCTGGCTAG AGATCCTGAT GATTGGTCTC
     3481 GTCTGGCGCT CCATGGAGCA CCCAGTGAAG CTACTGTTTG CTCCTAACTT GCTCTTGGAC
     3541 AGGAACCAGG GAAAATGTGT AGAGGGCATG GTGGAGATCT TCGACATGCT GCTGGCTACA
     3601 TCATCTCGGT TCCGCATGAT GAATCTGCAG GGAGAGGAGT TTGTGTGCCT CAAATCTATT
     3661 ATTTTGCTTA ATTCTGGAGT GTACACATTT CTGTCCAGCA CCCTGAAGTC TCTGGAAGAG
     3721 AAGGACCATA TCCACCGAGT CCTGGACAAG ATCACAGACA CTTTGATCCA CCTGATGGCC
     3781 AAGGCAGGCC TGACCCTGCA GCAGCAGCAC CAGCGGCTGG CCCAGCTCCT CCTCATCCTC
     3841 TCCCACATCA GGCACATGAG TAACAAAGGC ATGGAGCATC TGTACAGCAT GAAGTGCAAG
     3901 AACGTGGTGC CCCTCTATGA CCTGCTGCTG GAGGCGGCGG ACGCCCACCG CCTACATGCG
     3961 CCCACTAGCC GTGGAGGGGC ATCCGTGGAG GAGACGGACC AAAGCCACTT GGCCACTGCG
     4021 GGCTCTACTT CATCGCATTC CTTGCAAAAG TATTACATCA CGGGGGAGGC AGAGGGTTTC
     4081 CCTGCCACAG TCTGAGATAT Cgatcttatt aaagcagaac ttgtttattg cagcttataa
     4141 tggttacaaa taaagcaata gcatcacaaa tttcacaaat aaagcatttt tttcactgca
     4201 ttctagttgt ggtttgtcca aactcatcaa tgtatcttat catgtctggA GATCTGATCT
     4261 TTCCactcAA AACatATAAC TTCGTATAgc atacatTATA CGAAGTTATa tTCAAAAATC
     4321 TAGAcaGCGG CCGCCaCTCA AAATTTCTTC TATAAAGTAA CAAAACTTTT ATGAGGGACA
     4381 GCCCCCCCCC AAAGCCCCCA GGGATGTAAT TACGTCCCTC CCCCGCTAGG GGGCAGCAGC
     4441 GAGCCGCCCG GGGCTCCGCT CCGGTCCGGC GCTCCCCCCG CATCCCCGAG CCGGCAGCGT
     4501 GCGGGGACAG CCCGGGCACG GGGAAGGTGG CACGGGATCG CTTTCCTCTG AACGCTTCTC
     4561 GCTGCTCTTT GAGCCTGCAG ACACCTGGGG GGATACGGGG AAAAGGCCTC CAAGGCCtta
     4621 aTTCGgccgc aaggatctgc gatcgctccg gtgcccgtca gtgggcagag cgcacatcgc
     4681 ccacagtccc cgagaagttg gggggagggg tcggcaattg aacgggtgcc tagagaaggt
     4741 ggcgcggggt aaactgggaa agtgatgtcg tgtactggct ccgccttttt cccgagggtg
     4801 ggggagaacc gtatataagt gcagtagtcg ccgtgaacgt tctttttcgc aacgggtttg
     4861 ccgccagaac acagctgaag cttcgagggg ctcgcatctc tccttcacgc gcccgccgcc
     4921 ctacctgagg ccgccatcca cgccggttga gtcgcgttct gccgcctccc gcctgtggtg
     4981 cctcctgaac tgcgtccgcc gtctaggtaa gtttaaagct caggtcgaga ccgggccttt
     5041 gtccggcgct cccttggagc ctacctagac tcagccggct ctccacgctt tgcctgaccc
     5101 tgcttgctca actctacgtc tttgtttcgt tttctgttct gcgccgttac agatccaagc
     5161 tgtgaccggc gcctacgata tcgccaccat ggccagctcc gaggatgtca tcaaagagtt
     5221 tatgagattt aaggtcaaga tggagggaag cgtcaacgga cacgagttcg agattgaggg
     5281 agaaggagaa ggccggcctt acgagggcac acaaaccgct aagctcaagg tcacaaaagg
     5341 aggacccctc cccttctcct gggatattct gagccctcag ttccagtacg gaagcaaagc
     5401 ctatgttaaa caccctgccg acatccctga ctatctgaag ctctccttcc ctgaaggctt
     5461 caagtgggag agattcatga acttcgagga cggaggcgtg gtgacagtca cacaagatag
     5521 caccctccag gacggagagt ttatttataa ggtgaaactc agaggaacca acttcccctc
     5581 cgatggccct gtcatgcaaa aaaaaacaat gggatgggaa gcctccaccg agagaatgta
     5641 tcctgaggat ggcgctctga aaggcgaaat taaaatgaga ctgaaactca aagacggagg
     5701 acactacgat gccgaggtca aaacaaccta caaggccaag aaacaagtgc agctgcctgg
     5761 cgcctacatg actgatatta aactcgacat tatcagccat aatggggact acaccatcgt
     5821 ggaacaatat gagagagctg agggcagaca tagcacaggc gctggaGAGG GCAGAGGAAG
     5881 TCTTCTAACA TGCGGTGACG TGGAGGAGAA TCCCGGCCCT atgaccgagt acaagcccac
     5941 ggtgcgcctc gccacccgcg acgacgtccc cagggccgta cgcaccctcg ccgccgcgtt
     6001 cgccgactac cccgccacgc gccacaccgt cgatccggac cgccacatcg agcgggtcac
     6061 cgagctgcaa gaactcttcc tcacgcgcgt cgggctcgac atcggcaagg tgtgggtcgc
     6121 ggacgacggc gccgcggtgg cggtctggac cacgccggag agcgtcgaag cgggggcggt
     6181 gttcgccgag atcggcccgc gcatggccga gttgagcggt tcccggctgg ccgcgcagca
     6241 acagatggaa ggcctcctgg cgccgcaccg gcccaaggag cccgcgtggt tcctggccac
     6301 cgtcggcgtc tcgcccgacc accagggcaa gggtctgggc agcgccgtcg tgctccccgg
     6361 agtggaggcg gccgagcgcg ccggggtgcc cgccttcctg gagacctccg cgccccgcaa
     6421 cctccccttc tacgagcggc tcggcttcac cgtcaccgcc gacgtcgagg tgcccgaagg
     6481 accgcgcacc tggtgcatga cccgcaagcc cggtgcctga aatcaacctc tggaCGAAAt
     6541 tCCGCGGtta ttacaaaatt tgtgaaagat tgactggtat tcttaactat gttgctcctt
     6601 ttacgctatg tggatacgct gctttaatgc ctttgtatca GTTAACTTGT TTATTGCAGC
     6661 TTATAATGGT TACAAATAAA GCAATAGCAT CACAAATTTC ACAAATAAAG CATTTTTTTC
     6721 ACTGCATTCT AGTTGTGGTT TGTCCAAACT CATCAATGTA TCTTATCATG TCTGGAATTG
     6781 ACTCAAATGA TGTCAATTAG TCTATCAGAA GCTATCTGGT CTCCCTTCCG GGGGACAAGA
     6841 CATCCCTGTT TAATATTTAA ACAGCAGTGT TCCCAAACTG GGTTCTTATA TCCCTTGCTC
     6901 TGGTCAACCA GGTTGCAGGG TTTCCTGTCC TCACAGGAAC GAAGTCCCTA AAGAAACAGT
     6961 GGCAGCCAGG TTTAGCCCCG GAATTGACTG GATTCCTTTT TTAGGGCCCA TTGGTATGGC
     7021 TTTTTCCCCG TATCCCCCCA GGTGTCTGCA GGCTCAAAGA GCAGCGAGAA GCGTTCAGAG
     7081 GAAAGCGATC CCGTGCCACC TTCCCCGTGC CCGGGCTGTC CCCGCACGCT GCCGGCTCGG
     7141 GGATGCGGGG GGAGCGCCGG ACCGGAGCGG AGCCCCGGGC GGCTCGCTGC TGCCCCCTAG
     7201 CGGGGGAGGG ACGTAATTAC ATCCCTGGGG GCTTTGGGGG GGGGCTGTCC CTGATATCAA
     7261 ACatATAACT TCGTATAgca tacatTATAC GAAGTTATtT TATCACGTAA GTAGAACATG
     7321 AAAtaacCTA GATCGGATCC AAGGCTGAAA ACCTCTTGAT ACTTGAGAGT GAATATAAGT
     7381 CTAAATGCTG CTTTGTATAA TTTGTTCAGC TAAGGGATAG ATCGATCACA CTATTTAAGT
     7441 GAGCCCAGAT CAAAAAAGCA GATTGAAATT TTCTTTAGAA AAGATTCTCC ATGATTTGAA
     7501 TTGCATTCTC TTTAAACTCA CCAATGTAAT CATTTTGGGA GGAGGGAGAA CCCACTTGCT
     7561 TTCCAAATGG GTTTATTTAA ACCCACAAAC TCAAGAGGTT GTTGGGGGAA TTAGGAAAAT
     7621 AAGGGTTTTC AATGACCTAC ATTGCTAGGT AGAGGCTGTG ATCCATGGGA TTTCATTCTA
     7681 ATGACCATGT GAAGATGTTT GAGTCCTCCT TTGCCTTTCC TCAGAAAGAA TCCTTCTAAG
     7741 GCACAAATCC CTTAGATGGA TAATGTAAGG TATTGTTAAC TCACTCATAT TGAGATCATT
     7801 TTTAGAGATA CCAGGTTTTA TGTATCAGCA CTAGATGGTT CCACCCTCAT GGGATAAAAC
     7861 TGCTTACAAG TATTTTGAAA GAAAAACTGA CCAAAATTCT TAAATTGTTA CTAAGGCAAT
     7921 CATGCACAGG TGACGTATGT CTTATCTGAT TTGTTTTTAA CTCCTTGGTG CCCAAAGCTC
     7981 AGAAGGGAAT TCCACTGCCA GCAATGAACA TACCTGGAAA AGAAAGTAAG CAATCTGGGA
     8041 TTTTTTTTCT GGGTTAGTAA AGAATTTTTG CAATAAGTTT TATCAGTTGA TTCAAACTGA
     8101 TGTGCATCTT AATGATCAAA TGTGCACATT ACATAAATTA AGTCCACTGA TACAACTTCT
     8161 TACACATGTA TCTCTAGTAG CTCTGGCAAA CCCAATATCT GACACCACTT TGGACTCAAG
     8221 AGACTCAGTA ACGTATTATC CTGTTTATTT AGCTTGGTTT TAGCTGTGTT CTCTCTGGAT
     8281 AACCCACTTG ATGTTAGGAA CATTACTTCT CTGCTTATTC CATATTAATA CTGTGTTAGG
     8341 TATTTTAAGA AGCAAGTTAT TAAATAAGAA AAGTCAAAGT ATTAATTCTT ACCTTCTATT
     8401 ATCCTATATT AGCTTCAATA CATCCAAACC AAATGGCTGT TAGGTAGGAT CCCCGTCGAC
     8461 TGCATGCAAG CTTGGCGTAA TCATGGTCAT AGCTGTTTCC TGTGTGAAAT TGTTATCCGC
     8521 TCACAATTCC ACACAACATA CGAGCCGGAA GCATAAAGTG TAAAGCCTGG GGTGCCTAAT
     8581 GAGTGAGCTA ACTCACATTA ATTGCGTTGC GCTCACTGCC CGCTTTCCAG TCGGGAAACC
     8641 TGTCGTGCCA GCTGCATTAA TGAATCGGCC AACGCGCGGG GAGAGGCGGT TTGCGTATTG
     8701 GGCGCTCTTC CGCTTCCTCG CTCACTGACT CGCTGCGCTC GGTCGTTCGG CTGCGGCGAG
     8761 CGGTATCAGC TCACTCAAAG GCGGTAATAC GGTTATCCAC AGAATCAGGG GATAACGCAG
     8821 GAAAGAACAT GTGAGCAAAA GGCCAGCAAA AGGCCAGGAA CCGTAAAAAG GCCGCGTTGC
     8881 TGGCGTTTTT CCATAGGCTC CGCCCCCCTG ACGAGCATCA CAAAAATCGA CGCTCAAGTC
     8941 AGAGGTGGCG AAACCCGACA GGACTATAAA GATACCAGGC GTTTCCCCCT GGAAGCTCCC
     9001 TCGTGCGCTC TCCTGTTCCG ACCCTGCCGC TTACCGGATA CCTGTCCGCC TTTCTCCCTT
     9061 CGGGAAGCGT GGCGCTTTCT CATAGCTCAC GCTGTAGGTA TCTCAGTTCG GTGTAGGTCG
     9121 TTCGCTCCAA GCTGGGCTGT GTGCACGAAC CCCCCGTTCA GCCCGACCGC TGCGCCTTAT
     9181 CCGGTAACTA TCGTCTTGAG TCCAACCCGG TAAGACACGA CTTATCGCCA CTGGCAGCAG
     9241 CCACTGGTAA CAGGATTAGC AGAGCGAGGT ATGTAGGCGG TGCTACAGAG TTCTTGAAGT
     9301 GGTGGCCTAA CTACGGCTAC ACTAGAAGAA CAGTATTTGG TATCTGCGCT CTGCTGAAGC
     9361 CAGTTACCTT CGGAAAAAGA GTTGGTAGCT CTTGATCCGG CAAACAAACC ACCGCTGGTA
     9421 GCGGTGGTTT TTTTGTTTGC AAGCAGCAGA TTACGCGCAG AAAAAAAGGA TCTCAAGAAG
     9481 ATCCTTTGAT CTTTTCTACG GGGTCTGACG CTCAGTGGAA CGAAAACTCA CGTTAAGGGA
     9541 TTTTGGTCAT GAGATTATCA AAAAGGATCT TCACCTAGAT CCTTTTAAAT TAAAAATGAA
     9601 GTTTTAAATC AATCTAAAGT ATATATGAGT AAACTTGGTC TGACAGTTAC CAATGCTTAA
     9661 TCAGTGAGGC ACCTATCTCA GCGATCTGTC TATTTCGTTC ATCCATAGTT GCCTGACTCC
     9721 CCGTCGTGTA GATAACTACG ATACGGGAGG GCTTACCATC TGGCCCCAGT GCTGCAATGA
     9781 TACCGCGAGA CCCACGCTCA CCGGCTCCAG ATTTATCAGC AATAAACCAG CCAGCCGGAA
     9841 GGGCCGAGCG CAGAAGTGGT CCTGCAACTT TATCCGCCTC CATCCAGTCT ATTAATTGTT
     9901 GCCGGGAAGC TAGAGTAAGT AGTTCGCCAG TTAATAGTTT GCGCAACGTT GTTGCCATTG
     9961 CTACAGGCAT CGTGGTGTCA CGCTCGTCGT TTGGTATGGC TTCATTCAGC TCCGGTTCCC
    10021 AACGATCAAG GCGAGTTACA TGATCCCCCA TGTTGTGCAA AAAAGCGGTT AGCTCCTTCG
    10081 GTCCTCCGAT CGTTGTCAGA AGTAAGTTGG CCGCAGTGTT ATCACTCATG GTTATGGCAG
    10141 CACTGCATAA TTCTCTTACT GTCATGCCAT CCGTAAGATG CTTTTCTGTG ACTGGTGAGT
    10201 ACTCAACCAA GTCATTCTGA GAATAGTGTA TGCGGCGACC GAGTTGCTCT TGCCCGGCGT
    10261 CAATACGGGA TAATACCGCG CCACATAGCA GAACTTTAAA AGTGCTCATC ATTGGAAAAC
    10321 GTTCTTCGGG GCGAAAACTC TCAAGGATCT TACCGCTGTT GAGATCCAGT TCGATGTAAC
    10381 CCACTCGTGC ACCCAACTGA TCTTCAGCAT CTTTTACTTT CACCAGCGTT TCTGGGTGAG
    10441 CAAAAACAGG AAGGCAAAAT GCCGCAAAAA AGGGAATAAG GGCGACACGG AAATGTTGAA
    10501 TACTCATACT CTTCCTTTTT CAATATTATT GAAGCATTTA TCAGGGTTAT TGTCTCATGA
    10561 GCGGATACAT ATTTGAATGT ATTTAGAAAA ATAAACAAAT AGGGGTTCCG CGCACATTTC
    10621 CCCGAAAAGT GCCACCTGAC GTCTAAGAAA CCATTATTAT CATGACATTA ACCTATAAAA
    10681 ATAGGCGTAT CACGAGGCCC TTTCGTC
//
