LOCUS       Supplementary_Fi       18595 bp DNA     circular SYN 20-JUN-2022
DEFINITION  synthetic circular DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 18595)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Aug 30, 2023 from SnapGene Viewer 7.0.2
            https://www.snapgene.com
COMMENT     Annotated with pLannotate v1.2.0
FEATURES             Location/Qualifiers
     source          1..18595
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     rep_origin      919..1507
                     /direction=RIGHT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     CDS             1690..1782
                     /codon_start=1
                     /label=lacI (fragment)
                     /note="pLannotate"
                     /note="/database=snapgene"
                     /note="/fragment=True"
                     /note="/identity=100.0"
                     /note="/match_length=8.6"
                     /note="/other=CDS"
                     /translation="APNTQTASPRALADSLMQLARQVSRLESGQ"
     protein_bind    1795..1816
                     /label=CAP binding site
                     /note="pLannotate"
                     /note="/database=snapgene"
                     /note="/fragment=False"
                     /note="/identity=100.0"
                     /note="/match_length=100.0"
                     /note="/other=protein_bind"
     protein_bind    1795..1816
                     /label=CAP binding site
                     /bound_moiety="E. coli catabolite activator protein"
                     /note="CAP binding activates transcription in the presence 
                     of cAMP."
     promoter        1831..1861
                     /label=lac promoter
                     /note="promoter for the E. coli lac operon"
     protein_bind    1869..1885
                     /label=lac operator
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     primer_bind     1893..1909
                     /label=M13 rev
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     promoter        1930..1948
                     /label=T3 promoter
                     /note="promoter for bacteriophage T3 RNA polymerase"
     promoter        complement(1985..2006)
                     /label=SV40 promoter (fragment)
                     /note="pLannotate"
                     /note="/database=snapgene"
                     /note="/fragment=True"
                     /note="/identity=100.0"
                     /note="/match_length=6.1"
                     /note="/other=promoter"
     polyA_signal    2010..2234
                     /label=bGH poly(A) signal
                     /note="bovine growth hormone polyadenylation signal"
     intron          2308..2373
                     /label=small t intron
                     /note="SV40 (simian virus 40) small t antigen intron"
     CDS             complement(2375..2447)
                     /codon_start=1
                     /label=small t antigen (fragment)
                     /note="pLannotate"
                     /note="/database=snapgene"
                     /note="/fragment=True"
                     /note="/identity=100.0"
                     /note="/match_length=13.9"
                     /note="/other=CDS"
                     /translation="SL*RNLTSVV*HNWTNYLQRFKAL"
     CDS             complement(2450..3022)
                     /codon_start=1
                     /gene="Corynebacterium diphtheriae tox"
                     /product="diphtheria toxin fragment A"
                     /label=DTA
                     /translation="DDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYD
                     DDWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTKVLALKVDNAETIKKEL
                     GLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQAKALSVELEI
                     NFETRGKRGQDAMYEYMAQACAGNRVRR"
     promoter        complement(3049..3548)
                     /label=PGK promoter
                     /note="mouse phosphoglycerate kinase 1 promoter"
     misc_feature    3553..3585
                     /label=MCS (fragment)
                     /note="pLannotate"
                     /note="/database=snapgene"
                     /note="/fragment=True"
                     /note="/identity=100.0"
                     /note="/match_length=30.6"
                     /note="/other=misc_feature"
     misc_feature    3598..7942
                     /label=Rosa26 right arm
                     /note="right homology arm from intron 1 of the mouse Rosa26
                     gene (Soriano, 1999)"
     polyA_signal    8043..8154
                     /label=bGH poly(A) signal
                     /note="bovine growth hormone polyadenylation signal"
     misc_feature    complement(8161..8180)
                     /label=MCS (fragment)
                     /note="pLannotate"
                     /note="/database=snapgene"
                     /note="/fragment=True"
                     /note="/identity=100.0"
                     /note="/match_length=18.5"
                     /note="/other=misc_feature"
     primer_bind     8162..8178
                     /label=KS primer
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     misc_feature    8181..8769
                     /label=WPRE
                     /note="woodchuck hepatitis virus posttranscriptional 
                     regulatory element"
     CDS             8287..8298
                     /codon_start=1
                     /product="Factor Xa recognition and cleavage site"
                     /label=Factor Xa site
                     /translation="IEGR"
     CDS             complement(8778..9461)
                     /codon_start=1
                     /label=mClover3
                     /note="pLannotate"
                     /note="/database=fpbase"
                     /note="/fragment=False"
                     /note="/identity=100.0"
                     /note="/match_length=95.4"
                     /note="/other=CDS"
                     /translation="MVSKGEELFTGVVPILVELDGDVNGHKFSVRGEGEGDATNGKLTL
                     KFICTTGKLPVPWPTLVTTFGYGVACFSRYPDHMKQHDFFKSAMPEGYVQERTISFKDD
                     GTYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNFNSHYVYITADKQKNCIK
                     ANFKIRHNVEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSHQSKLSKDPNEKRDHMVLL
                     EFVTAA"
     CDS             complement(9579..9716)
                     /codon_start=1
                     /label=Elk1 (fragment)
                     /note="pLannotate"
                     /note="/database=swissprot"
                     /note="/fragment=True"
                     /note="/identity=95.7"
                     /note="/match_length=10.7"
                     /note="/other=CDS"
                     /translation="PMKGRKPRDLELPLSPSLLGGQGPERTPGSGTSSGLQAPGPALSP
                     S"
     CDS             complement(9714..9770)
                     /codon_start=1
                     /product="2A peptide from porcine teschovirus-1 
                     polyprotein"
                     /label=P2A
                     /note="Eukaryotic ribosomes fail to insert a peptide bond 
                     between the Gly and Pro residues, yielding separate 
                     polypeptides."
                     /translation="ATNFSLLKQAGDVEENPGP"
     CDS             complement(9786..9872)
                     /codon_start=1
                     /label=3xHA
                     /note="pLannotate"
                     /note="/database=snapgene"
                     /note="/fragment=False"
                     /note="/identity=95.6"
                     /note="/match_length=100.0"
                     /note="/other=CDS"
                     /translation="YPYDVPDYAGYPYDVPDYAGYPYDVPDYA"
     CDS             complement(9873..10583)
                     /codon_start=1
                     /label=mTagBFP2
                     /note="pLannotate"
                     /note="/database=fpbase"
                     /note="/fragment=False"
                     /note="/identity=100.0"
                     /note="/match_length=100.0"
                     /note="/other=CDS"
                     /translation="MVSKGEELIKENMHMKLYMEGTVDNHHFKCTSEGEGKPYEGTQTM
                     RIKVVEGGPLPFAFDILATSFLYGSKTFINHTQGIPDFFKQSFPEGFTWERVTTYEDGG
                     VLTATQDTSLQDGCLIYNVKIRGVNFTSNGPVMQKKTLGWEAFTETLYPADGGLEGRND
                     MALKLVGGSHLIANAKTTYRSKKPAKNLKMPGVYYVDYRLERIKEANNETYVEQHEVAV
                     ARYCDLPSKLGHKLN"
     regulatory      10580..10589
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
     CDS             complement(10602..10979)
                     /codon_start=1
                     /gene="HIST1H2BJ"
                     /product="human histone H2B"
                     /label=H2B
                     /translation="MPEPAKSAPAPKKGSKKAVTKAQKKGGKKRKRSRKESYSIYVYKV
                     LKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLP
                     GELAKHAVSEGTKAITKYTSAK"
     CDS             complement(10980..11036)
                     /codon_start=1
                     /product="2A peptide from porcine teschovirus-1 
                     polyprotein"
                     /label=P2A
                     /note="Eukaryotic ribosomes fail to insert a peptide bond 
                     between the Gly and Pro residues, yielding separate 
                     polypeptides."
                     /translation="ATNFSLLKQAGDVEENPGP"
     CDS             complement(11046..11753)
                     /codon_start=1
                     /product="monomeric red fluorescent protein derived from 
                     mRuby2, with improved brightness and photostability (Bajar 
                     et al., 2016)"
                     /label=mRuby3
                     /translation="VSKGEELIKENMRMKVVMEGSVNGHQFKCTGEGEGRPYEGVQTMR
                     IKVIEGGPLPFAFDILATSFMYGSRTFIKYPADIPDFFKQSFPEGFTWERVTRYEDGGV
                     VTVTQDTSLEDGELVYNVKVRGVNFPSNGPVMQKKTKGWEPNTEMMYPADGGLRGYTDI
                     ALKVDGGGHLHCNFVTTYRSKKTVGNIKMPGVHAVDHRLERIEESDNETYVVQREVAVA
                     KYSNLGGGMDELYK"
     CDS             complement(11760..13715)
                     /codon_start=1
                     /label=Foxo1
                     /note="pLannotate"
                     /note="/database=swissprot"
                     /note="/fragment=False"
                     /note="/identity=98.9"
                     /note="/match_length=100.0"
                     /note="/other=CDS"
                     /translation="MAEAPQVVETDPDFEPLPRQRSCTWPLPRPEFNQSNSTTSSPAPS
                     GGAAANPDAAASLASASAVSTDFMSNLSLLEESEDFARAPGCVAVAAAAAASRGLCGDF
                     QGPEAGCVHPAPPQPPPTGPLSQPPPVPPSAAAAAGPLAGQPRKTSSSRRNAWGNLSYA
                     DLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNAIRRNLALHSKFIR
                     VQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRGRAAKKKASLRSGQEGP
                     GDSPGSQFSKWPASPGSHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGDGDV
                     HSLVYPPSAAKMASTLPSLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGSMMQQT
                     PCYSFAPPNTSLNSPSPNYSKYTYGQSSMSPLPQMPMQTLQDSKSSYGGLNQYNCAPGL
                     LKELLTSDSPPHNDIMSPVDPGVAQPNSRVLGQNVMMGPNSVMPAYGSQASHNKMMYPS
                     SHTHPGHAQQTASVNGRTLPHVVNTMPHTSAMNRLTPVKTPLQVPLSHPMQMSALGNYS
                     SVSSCNGYGRMGVLHQEKLPSDLDGMFIERLDCDMESIIRNDPMDGDTLDFNFDNVLPN
                     QSFPHSVKTTTHSWVSG"
     variation       11859..11861
                     /label=Leu -> Pro
     variation       11994..11996
                     /label=Ser -> Asn
     variation       12171..12173
                     /label=Asn -> Tyr
     variation       12891..12893
                     /label=Glu -> Arg
     variation       13071..13073
                     /label=Ser -> Ala
     variation       13080..13082
                     /label=His -> Arg
     variation       13089..13091
                     /label=Ser -> Ala
     regulatory      13712..13721
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
     protein_bind    13752..13785
                     /label=loxP
                     /bound_moiety="Cre recombinase"
                     /note="Cre-mediated recombination occurs in the 8-bp core 
                     sequence (GCATACAT)."
     polyA_signal    13814..13948
                     /label=SV40 poly(A) signal
                     /note="SV40 polyadenylation signal"
     CDS             complement(13971..14054)
                     /codon_start=1
                     /label=large T antigen (fragment)
                     /note="pLannotate"
                     /note="/database=snapgene"
                     /note="/fragment=True"
                     /note="/identity=100.0"
                     /note="/match_length=3.9"
                     /note="/other=CDS"
                     /translation="DHNQPYHICRGFTCFKKPPTPPPEPET"
     polyA_signal    14068..14202
                     /label=SV40 poly(A) signal
                     /note="SV40 polyadenylation signal"
     CDS             complement(14225..14308)
                     /codon_start=1
                     /label=large T antigen (fragment)
                     /note="pLannotate"
                     /note="/database=snapgene"
                     /note="/fragment=True"
                     /note="/identity=100.0"
                     /note="/match_length=3.9"
                     /note="/other=CDS"
                     /translation="DHNQPYHICRGFTCFKKPPTPPPEPET"
     polyA_signal    14322..14456
                     /label=SV40 poly(A) signal
                     /note="SV40 polyadenylation signal"
     CDS             complement(14479..14562)
                     /codon_start=1
                     /label=large T antigen (fragment)
                     /note="pLannotate"
                     /note="/database=snapgene"
                     /note="/fragment=True"
                     /note="/identity=100.0"
                     /note="/match_length=3.9"
                     /note="/other=CDS"
                     /translation="DHNQPYHICRGFTCFKKPPTPPPEPET"
     polyA_signal    14604..15065
                     /label=PGK poly(A) signal
                     /note="mouse phosphoglycerate kinase 1 polyadenylation 
                     signal"
     CDS             complement(15075..15878)
                     /codon_start=1
                     /gene="aph(3')-II (or nptII)"
                     /product="aminoglycoside phosphotransferase from Tn5"
                     /label=NeoR/KanR
                     /note="confers resistance to neomycin, kanamycin, and G418 
                     (Geneticin(R))"
                     /translation="MGSAIEQDGLHAGSPAAWVERLFGYDWAQQTIGCSDAAVFRLSAQ
                     GRPVLFVKTDLSGALNELQDEAARLSWLATTGVPCAAVLDVVTEAGRDWLLLGEVPGQD
                     LLSSHLAPAEKVSIMADAMRRLHTLDPATCPFDHQAKHRIERARTRMEAGLVDQDDLDE
                     EHQGLAPAELFARLKARMPDGDDLVVTHGDACLPNIMVENGRFSGFIDCGRLGVADRYQ
                     DIALATRDIAEELGGEWADRFLVLYGIAAPDSQRIAFYRLLDEFF"
     promoter        complement(15892..16392)
                     /label=PGK promoter
                     /note="mouse phosphoglycerate kinase 1 promoter"
     protein_bind    16422..16455
                     /label=loxP
                     /bound_moiety="Cre recombinase"
                     /note="Cre-mediated recombination occurs in the 8-bp core 
                     sequence (GCATACAT)."
     misc_feature    16505..16608
                     /label=Ad SA
                     /note="adenovirus major late transcript splice acceptor 
                     (Friedrich and Soriano, 1991)"
     misc_feature    16610..17692
                     /label=Rosa26 left arm
                     /note="left homology arm from intron 1 of the mouse Rosa26 
                     gene (Soriano, 1999)"
     promoter        complement(17711..17729)
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
     CDS             17737..17892
                     /codon_start=1
                     /label=lacZ-alpha (fragment)
                     /note="pLannotate"
                     /note="/database=snapgene"
                     /note="/fragment=True"
                     /note="/identity=100.0"
                     /note="/match_length=89.7"
                     /note="/other=CDS"
                     /translation="SLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQ
                     LRSLNGE"
     primer_bind     complement(17739..17755)
                     /label=M13 fwd
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     rep_origin      complement(17896..18351)
                     /direction=LEFT
                     /label=f1 ori
                     /note="f1 bacteriophage origin of replication; arrow 
                     indicates direction of (+) strand synthesis"
     promoter        18378..18482
                     /gene="bla"
                     /label=AmpR promoter
     CDS             join(18483..18595,1..748)
                     /codon_start=1
                     /gene="bla"
                     /product="beta-lactamase"
                     /label=AmpR
                     /note="confers resistance to ampicillin, carbenicillin, and
                     related antibiotics"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
ORIGIN
        1 gggtgcacga gtgggttaca tcgaactgga tctcaacagc ggtaagatcc ttgagagttt
       61 tcgccccgaa gaacgttttc caatgatgag cacttttaaa gttctgctat gtggcgcggt
      121 attatcccgt attgacgccg ggcaagagca actcggtcgc cgcatacact attctcagaa
      181 tgacttggtt gagtactcac cagtcacaga aaagcatctt acggatggca tgacagtaag
      241 agaattatgc agtgctgcca taaccatgag tgataacact gcggccaact tacttctgac
      301 aacgatcgga ggaccgaagg agctaaccgc ttttttgcac aacatggggg atcatgtaac
      361 tcgccttgat cgttgggaac cggagctgaa tgaagccata ccaaacgacg agcgtgacac
      421 cacgatgcct gtagcaatgg caacaacgtt gcgcaaacta ttaactggcg aactacttac
      481 tctagcttcc cggcaacaat taatagactg gatggaggcg gataaagttg caggaccact
      541 tctgcgctcg gcccttccgg ctggctggtt tattgctgat aaatctggag ccggtgagcg
      601 tgggtctcgc ggtatcattg cagcactggg gccagatggt aagccctccc gtatcgtagt
      661 tatctacacg acggggagtc aggcaactat ggatgaacga aatagacaga tcgctgagat
      721 aggtgcctca ctgattaagc attggtaact gtcagaccaa gtttactcat atatacttta
      781 gattgattta aaacttcatt tttaatttaa aaggatctag gtgaagatcc tttttgataa
      841 tctcatgacc aaaatccctt aacgtgagtt ttcgttccac tgagcgtcag accccgtaga
      901 aaagatcaaa ggatcttctt gagatccttt ttttctgcgc gtaatctgct gcttgcaaac
      961 aaaaaaacca ccgctaccag cggtggtttg tttgccggat caagagctac caactctttt
     1021 tccgaaggta actggcttca gcagagcgca gataccaaat actgttcttc tagtgtagcc
     1081 gtagttaggc caccacttca agaactctgt agcaccgcct acatacctcg ctctgctaat
     1141 cctgttacca gtggctgctg ccagtggcga taagtcgtgt cttaccgggt tggactcaag
     1201 acgatagtta ccggataagg cgcagcggtc gggctgaacg gggggttcgt gcacacagcc
     1261 cagcttggag cgaacgacct acaccgaact gagataccta cagcgtgagc tatgagaaag
     1321 cgccacgctt cccgaaggga gaaaggcgga caggtatccg gtaagcggca gggtcggaac
     1381 aggagagcgc acgagggagc ttccaggggg aaacgcctgg tatctttata gtcctgtcgg
     1441 gtttcgccac ctctgacttg agcgtcgatt tttgtgatgc tcgtcagggg ggcggagcct
     1501 atggaaaaac gccagcaacg cggccttttt acggttcctg gccttttgct ggccttttgc
     1561 tcacatgttc tttcctgcgt tatcccctga ttctgtggat aaccgtatta ccgcctttga
     1621 gtgagctgat accgctcgcc gcagccgaac gaccgagcgc agcgagtcag tgagcgagga
     1681 agcggaagag cgcccaatac gcaaaccgcc tctccccgcg cgttggccga ttcattaatg
     1741 cagctggcac gacaggtttc ccgactggaa agcgggcagt gagcgcaacg caattaatgt
     1801 gagttagctc actcattagg caccccaggc tttacacttt atgcttccgg ctcgtatgtt
     1861 gtgtggaatt gtgagcggat aacaatttca cacaggaaac agctatgacc atgattacgc
     1921 caagcgcgca attaaccctc actaaaggga acaaaagctg ggtaccgggc cccccctcga
     1981 gccccagctg gttctttccg cctcagaagc catagagccc accgcatccc cagcatgcct
     2041 gctattgtct tcccaatcct cccccttgct gtcctgcccc accccacccc ccagaataga
     2101 atgacaccta ctcagacaat gcgatgcaat ttcctcattt tattaggaaa ggacagtggg
     2161 agtggcacct tccagggtca aggaaggcac gggggagggg caaacaacag atggctggca
     2221 actagaaggc acagtcgagg ctgatcagcg agctctagga tctgcattcc accactgctc
     2281 ccattcatca gttccatagg ttggaatcta aaatacacaa acaattagaa tcagtagttt
     2341 aacacattat acacttaaaa attttatatt taccttagag ctttaaatct ctgtaggtag
     2401 tttgtccaat tatgtcacac cacagaagta aggttccttc acaaagagat cgcctgacac
     2461 gatttcctgc acaggcttga gccatatact catacatcgc atcttggcca cgttttccac
     2521 gggtttcaaa attaatctca agttctacgc ttaacgcttt cgcctgttcc cagttattaa
     2581 tatattcaac gctagaactc ccctcagcga agggaaggct gagcactaca cgcgaagcac
     2641 catcaccgaa ccttttgata aactcttccg ttccgacttg ctccatcaac ggttcagtga
     2701 gacttaaacc taactctttc ttaatagttt cggcattatc cacttttagt gcgagaacct
     2761 tcgtcagtcc tggatacgtc actttgacca cgcctccagc ttttccagag agcgggtttt
     2821 cattatctac agagtatccc gcagcgtcgt atttattgtc ggtactataa aaccctttcc
     2881 aatcatcgtc ataatttcct tgtgtaccag attttggctt ttgtatacct ttttgaatgg
     2941 aatctacata accaggttta gtcccgtggt acgaagaaaa gttttccatc acaaaagatt
     3001 tagaagaatc aacaacatca tcaggatcca tggcgaggac ctgcaggtcg aaaggcccgg
     3061 agatgaggaa gaggagaaca gcgcggcaga cgtgcgcttt tgaagcgtgc agaatgccgg
     3121 gcctccggag gaccttcggg cgcccgcccc gcccctgagc ccgcccctga gcccgccccc
     3181 ggacccaccc cttcccagcc tctgagccca gaaagcgaag gagcaaagct gctattggcc
     3241 gctgccccaa aggcctaccc gcttccattg ctcagcggtg ctgtccatct gcacgagact
     3301 agtgagacgt gctacttcca tttgtcacgt cctgcacgac gcgagctgcg gggcgggggg
     3361 gaacttcctg actaggggag gagtagaagg tggcgcgaag gggccaccaa agaacggagc
     3421 cggttggcgc ctaccggtgg atgtggaatg tgtgcgaggc cagaggccac ttgtgtagcg
     3481 ccaagtgccc agcggggctg ctaaagcgca tgctccagac tgccttggga aaagcgcctc
     3541 ccctacccgg tagaattcga tatcaagctt atcgataccg tcgacggtat cgataagcta
     3601 gatgtcctga aatatttcta tcagaacaag gtagtataaa gctggtaggt atacaaaacg
     3661 ctagactagt ttctatccct gacccttaat ctgctagtat atccgtagga agttgcttaa
     3721 gtgccactag taccaacagc ctctgttaga gtgaacagta gattttaatg aagggccaat
     3781 aaagaccact taagactact gactgaatta aaaatccacc cagtggagtt agtattggtt
     3841 atagttatat aacaaaatat ccaacttagc caggcgtggt ggtgcacgcc tttaatcccg
     3901 gcactcagga ggcagaggca ggcggatttc tgagttcgag gccagcctgg tctacaaagt
     3961 gagttccggg acagccgggg ctatacagag aaaccctgtc tcgaaaaacc aaaaaaaaaa
     4021 aaaaaaaagg aaaaaaaata tggcttgaaa acatgctatt gttgtcaaaa ggagatccaa
     4081 acaagtattt ctttgaacaa aaattatgta gaaaacaggg tgataaagaa caagggcttt
     4141 ttaaaaaagg ccagcattat ttgagatata caagtgactc caattcaagc ctaaaggcca
     4201 ctcaatgctc actaacagtg ctaatcagaa tcaattcctt agcccagtca aaaatagtcc
     4261 tgaatatctt ctggataaac atgtcctcca acatataaac tagtatacac taacaaaacg
     4321 tctcaacttc aaggtgaaat gcttgactcc tagacttgtg acccagcaaa gtgctctata
     4381 ggtagggtta ctaggtcaga gagtcttgcc tgcaaaccac aattatacaa ttccaccaaa
     4441 tgtaagacat gtaaaaatga cttatttagc tcaggttttg aaaattaaaa atcaaaccca
     4501 caaagaccta actttcacat taagtacaaa tgtttaacat atataacatg ttttgccttg
     4561 atatatgaaa tcatatgaca tcacctgaca ggaaacttaa gtttatttga acaacaatca
     4621 gcctaaggta ggcctagcac atgatcagga tagtgcaggg aaacccaaag aagtgcttct
     4681 gagtataaac caagagacct cgaaatagca gctttgttct gtatctcatg ggctttaact
     4741 atcacttgaa aacaatttca caaatcacaa aaccaacatt tgtttagttt ccaactctgc
     4801 ctattcaccg gagaaatcca tgtcccaatt tgatggggga aaacttgaat gaaatattat
     4861 ttggaatatt ttaatatccc tgtgtatatg cagatggttt aaagacaggt aaccttaact
     4921 gtagtttctt ggttgtctgc cttgtttttt gaaatatgct ctcaccagga gcctgccaag
     4981 taactactct tgtgtgctca gcaagtccta gggatccctt aagcatgctc taacaggcct
     5041 ggcttttttt ttttaaaaag taggttgcgg tgataataat tcaagttttc atcacttgaa
     5101 acacatttta ccaactatca cccaagctcc cttagtgtgt cccctataaa agaatctgac
     5161 ctgcaagttc caaaagtatt actacatttt aaccttagta ttcaggagac aaaagcaggc
     5221 agaactttag tctacatatc ttgttgcaga tcaggcagag atacatagtg agaccctgcc
     5281 tcaggaaaag ctatcatttt tatattcaca gtaagcaaat taacattaaa agtcagaaat
     5341 tcttaatttg actttggctg tgaagaattt ggattctctg gatttgaaac tagaaaatct
     5401 gattaagcga tgcaacagtt tctgtatact aaaactctaa gacccttggt tctaaagata
     5461 ccacatttaa aaaaaaaagt taagtataag acaaaaagcc ttaatagctc ttttataggg
     5521 gagggactca tttaatatta gtccacctca ctcctcataa ctattttatg aggtttatta
     5581 tataacccat tttttaaaaa aaaaattaaa ggacaatttt agtgtttgaa agatttccca
     5641 accccacccc ggaaatcagg ctgcaaatct cagcagctgc ccttagaagg caaaaagcca
     5701 tgccatttaa gccatgggaa gttagtagca aacaagagac cacatggcag gaaggaggct
     5761 ttaaagaaag cccacagtgt caaaagaccc aaccaacagc agagacagaa aaaataatac
     5821 ccaaatctca tcagaaaggt agacggattt agccacatcc atagtggctc attagggaat
     5881 gcttcaatta taattttatg aaatctcaga gcccccctcc ccaacagggt ttctgtgtgt
     5941 attcccggct atcctagata gaacttgatg tgtagaccag gctgggctca aactcagaga
     6001 tctgcctgtc tctgcctcca gagtgctggg attaaaggca taaaggcaag caccaccact
     6061 ggctggctaa actctggccc tacatttttg aaatccaaaa ttatcattac ttgctttcat
     6121 gtttagtaat ggctgcagac ttagctttca gctttgtata gatgaagcac aaaagttaag
     6181 taaagctagc agtttaaaca aataggatac tagaagttca atttttattt ctttattgct
     6241 tagtgtaaga gaaaagacat taaagtctgc attggtcttc tgtatcccac aagtctgcag
     6301 ttatggctcc tctgtccaca gttacacttc aaataaaaat tagttccttg gtaacatttc
     6361 cagtgcttaa agagtaattt gattattggc taccatattg gaacaaacac aaagtatttc
     6421 attacttcag taaattctac tggagacagt attctcttta aaaaaaaaaa aaaagaagaa
     6481 gaaggaggat ttatttattt aatgtgaata cacttgtggt cttcagacac accagaagag
     6541 ggcatcagat cccattacag atggttgtga gccaccatgt ggttgctggg aattgaactc
     6601 aggacttctg gaagagcagt ctgtgctctt gaactccgag ccacctctcc agcccccgga
     6661 tagtattatt atagagcaca agcacacaca acacaacaac ctaaaaacca agcttcacaa
     6721 atacatttgt tgcttaatca ttttacttgt gtttggctac aagtcaagca aaattatagg
     6781 tcctgaagaa gcttggcaaa atcacattta gaccagcaat aacgtgtaga atgccatgag
     6841 tcaagccagt ccaagagaaa gcactgctta aatagaaaaa atacaagctc acaagacctt
     6901 aggtcaggaa agacaacaaa cacctgaact ttgcattcca aaaggaacca ccttttacag
     6961 atgtgtacaa tgacaaaatt ttagtaagca gtaatcaata ccatgtggct caataatgaa
     7021 atataccttt taatgtctta aaatatcagc ctggcaatat gtaagataca tcaggtaata
     7081 ttgggggagg agacatccac ccggaaacca ttaatggtta atagctcagt ttataaatgg
     7141 agaaaaagga gagaggcatt catgggagtg gaaagttaag ctttaggttg gattctcaat
     7201 acatctattg ttgtaaaact ccctggactg agaataggcc caaatgtgga acaccacctg
     7261 acgggagagg tgatagacac tgaaaattaa ggatcaaggc aaaggatcaa caaaaagtgt
     7321 actaaggagt tataaaagaa ctgcagtgtt gaggccccag ctacagcctc gatttgtggt
     7381 gtatgtaact aatctgtctg gtttcatgag tcatcagact tctaagatca ggaaagggaa
     7441 aatgccaatg ctctgtctag gggttggata agccagtata ataaatgaaa atggggctaa
     7501 aatgagtgtt ctaaaatacc ttttgataag gctgcagaag gagcgggaga aatggatatg
     7561 aagtactggg ctctttaaaa atgattaaaa ttctgcttac atagtctaac tcgcgacact
     7621 gtaatttcat actgtagtaa ggatctcaag caggagagta taaaactcgg gtgagcatgt
     7681 ctttaatcta cctcgatgga aaatactccg aggcggatca caagcaataa taacctgtag
     7741 ttttgctgca taaaacccca gatgactacc tatcctccca ttttccttat ttgcccctat
     7801 taaaaaactt cccgacaaaa ccgaaaatct gtgggaagtc ttgtccctcc aattttacac
     7861 ctgttcaatt cccctgcagg acaacgccca cacaccaggt tagcctttaa gcctgcccag
     7921 aagactcccg cccatcttct agaaagctta agtttaaacg ctagctgtct tcccaatcct
     7981 cccccttgct gtcctgcccc accccacccc ccagaataga atgacaccta ctcagacaat
     8041 gcgatgcaat ttcctcattt tattaggaaa ggacagtggg agtggcacct tccagggtca
     8101 aggaaggcac gggggagggg caaacaacag atggctggca actagaaggc acagtcgagg
     8161 tcgaggtcga cggtatcgat gcggggaggc ggcccaaagg gagatccgac tcgtctgagg
     8221 gcgaaggcga agacgcggaa gaggccgcag agccggcagc aggccgcggg aaggaaggtc
     8281 cgctggattg agggccgaag ggacgtagca gaaggacgtc ccgcgcagaa tccaggtggc
     8341 aacacaggcg agcagccaag gaaaggacga tgatttcccc gacaacacca cggaattgtc
     8401 agtgcccaac agccgagccc ctgtccagca gcgggcaagg caggcggcga tgagttccgc
     8461 cgtggcaata gggaggggga aagcgaaagt cccggaaagg agctgacagg tggtggcaat
     8521 gccccaacca gtgggggttg cgtcagcaaa cacagtgcac accacgccac gttgcctgac
     8581 aacgggccac aactcctcat aaagagacag caaccaggat ttatacaagg aggagaaaat
     8641 gaaagccata cgggaagcaa tagcatgata caaaggcatt aaagcagcgt atccacatag
     8701 cgtaaaagga gcaacatagt taagaatacc agtcaatctt tcacaaattt tgtaatccag
     8761 aggttgatta tcgactaggc ggcggtcacg aactccagca ggaccatgtg atcgcgcttc
     8821 tcgttggggt ctttgctcag cttggactga tggctcaggt agtggttgtc gggcagcagc
     8881 acggggccgt cgccgatggg ggtgttctgc tggtagtggt cggcgagctg cacgctgccg
     8941 tcctcaacgt tgtggcggat cttgaagtta gccttgatgc agttcttctg cttgtcggcc
     9001 gtgatataga cgtagtggct gttgaagttg tactccagct tgtgccccag gatgttgccg
     9061 tcctccttga agtcgatgcc cttcagctcg atgcggttca ccagggtgtc gccctcgaac
     9121 ttcacctcgg cgcgggtctt gtaggtaccg tcgtccttga aagagatggt gcgctcctgg
     9181 acgtagcctt cgggcatggc ggacttgaag aagtcgtgct gcttcatgtg gtcggggtag
     9241 cggctgaagc aggccacgcc gtagccgaag gtggtcacga gggtgggcca gggcacgggc
     9301 agcttgccgg tggtgcagat gaacttcagg gtcagcttgc cgttggtggc atcgccctcg
     9361 ccctcgccgc ggacgctgaa cttgtggccg tttacgtcgc cgtccagctc gaccaggatg
     9421 ggcaccaccc cggtgaacag ctcctcgccc ttgctcacca tactagtgga tgggaattga
     9481 aagctggact ggagggtcag gcgctccagc cttgacgaca ccgatggggt acgtggcttc
     9541 ttcgatggcg tcgctgggtc ctcgagaccg ctacgcttgc tgggcgaaag cgctggcccc
     9601 ggtgcctgaa gaccagagct tgttcctgat cctggagtcc gttcaggtcc ctggccaccc
     9661 agcaggcttg ggctaagtgg aagttccagg tcccgaggct ttcggccctt cataggtcca
     9721 gggttctcct ccacgtctcc agcctgcttc agcaggctga agttagtagc tccgcttcct
     9781 ccgccagcgt aatctggaac gtcatatgga tatcctgcat agtccgggac gtcataggga
     9841 tagcccgcat agtcaggaac atcgtatggg tagttgagct tatgacccaa cttactaggc
     9901 aaatcacagt agcgggcgac ggcgacttcg tgctgctcga cgtaggtttc gttgttagct
     9961 tccttaatgc gctccagcct atagtccacg tagtacacac cgggcatctt caggttcttc
    10021 gctggcttct tactacggta cgtagtcttg gcattggcta taaggtgcga accgcccacc
    10081 agcttcagag ccatatcgtt gcgaccttca agaccgccat cggcggggta cagcgtctcc
    10141 gtaaaggcct cccatccgag cgtctttttc tgcataaccg ggccgttcga ggtaaagttc
    10201 acgccgcgta tcttcacgtt gtaaatcaag caaccatcct gcaggctagt atcttgggtg
    10261 gcagtcagaa ctccgccgtc ctcataggta gtaacgcgtt cccatgtgaa gccttcaggg
    10321 aaggattgct tgaagaaatc tggtattccc tgagtatgat tgatgaatgt cttgctgcca
    10381 tagaggaaac tggtggccag gatatcgaat gcaaatggca gtggacctcc ctcgacaact
    10441 ttaatacgca tggtctgtgt gccctcgtag ggctttccct caccctcgct ggtgcactta
    10501 aagtggtggt tgtcgacggt tccctccata tacagcttca tgtgcatatt ctctttgatc
    10561 agctcctctc ccttcgaaac catggtggcg accggtggat ccttagcgct ggtgtacttg
    10621 gtgatggcct tagtaccctc ggacacggcg tgcttggcca actccccagg cagcagcagg
    10681 cgcacggccg tctggatctc cctggaggtg atggtcgagc gcttgttgta atgcgccagg
    10741 cgggaagcct cacctgcgat gcgctcgaaa atgtcgttca caaacgaatt catgatgccc
    10801 atggccttgg acgaaatgcc ggtgtcaggg tggacctgct tcagaacctt gtacacatag
    10861 atggaatagc tctccttgcg gctgcgcttg cgcttcttgc cgcctttctt ctgcgcctta
    10921 gtcaccgcct tcttggagcc ctttttcggg gcgggagcag acttcgctgg ctctggcata
    10981 ggtccagggt tctcctccac gtctccagcc tgcttcagca ggctgaagtt agtagctccg
    11041 cttcccttgt acagctcgtc catgccacca ccaaggttgc tgtatttggc aactgccact
    11101 tctctttgca ctacgtaggt ttcattgtca ctctcctcga tcctttccag gcggtgatca
    11161 acggcatgga caccgggcat cttgatgttc ccgacggtct tttttgacct gtaagttgtc
    11221 acgaagttgc agtgcagatg gccaccacca tcaactttca gtgcgatgtc agtgtatcct
    11281 ctcagaccac catctgctgg atacatcatc tctgtattgg gctcccaacc cttggtcttc
    11341 ttctgcatca cgggaccatt ggagggaaag tttacccctc tgaccttgac gttgtagacg
    11401 agctcgccat cctcaaggct ggtgtcctgc gtgacggtga cgactccacc atcttcgtat
    11461 ctcgtaactc tttcccaagt aaaaccctca ggaaaggact gtttaaagaa atcagggatg
    11521 tcggccgggt acttgataaa ggtacggctg ccatacatga acgacgtggc aagaatgtca
    11581 aaggcaaatg gcaggggtcc tccctcgatg actttgatcc tcatggtttg cactccctcg
    11641 tacggtctgc cttctccttc acctgtgcat ttgaattggt ggccgttgac cgaaccttcc
    11701 atgaccacct tcatacgcat attttccttg atcagctctt cgcccttaga cacagatcct
    11761 cctgacaccc agctgtgtgt tgtagtcttg acactgtgtg ggaagctttg gttgggcaac
    11821 acattatcaa agttaaaatc caaggtatct ccatccatgg ggtcattccg aatgatggac
    11881 tccatgtcac agtccaagcg ctcaataaac atgccatcca agtcacttgg gagcttctcc
    11941 tggtggagga cacccatcct accatagcca ttgcagctgc tcaccgagga gtagttgccc
    12001 agggcactca tctgcatggg gtgggacaga ggcacttgta aaggtgtctt cacgggggtc
    12061 aagcggttca tggcagatgt gtgaggcatg gtgttcacca catggggcag ggtacggccg
    12121 ttgaccgaag ccgtttgctg tgcatgtcca gggtgggtgt gggagctggg gtacatcatt
    12181 ttgttatgag atgcctggct gccatacgct ggcatgaccg aattagggcc catcattaca
    12241 ttttggccca ggacccgact gttgggttgg gccactccgg gatcaaccgg tgacataatg
    12301 tcattgtggg gaggagagtc agaagtcaac aactctttca agagtcctgg ggcacagtta
    12361 tactggttca atcctccgta acttgatttg ctgtcctgaa gtgtctgcat aggcatctgg
    12421 ggcaaagggc tcatgctgga ttggccgtat gtgtactttg agtagtttgg actgggtgaa
    12481 tttagactgg tgtttggcgg tgcaaacgaa tagcatggtg tctgctgcat catgctgcca
    12541 ggcgaggact gagtggacac agttaaagat gttggggacg agagaaggtt gagattatcc
    12601 agaaggttct ccatgttttc tggattgctg atttcagaca gactgggcag cgtagacgcc
    12661 atcttggcag cagagggtgg atacaccagg gaatgcacgt ccccatctcc caggtcatcc
    12721 tgctctgtca tgatgggaga aagtctccca ctgatggtac tagcatttga gctggttcga
    12781 ggacgaaatg tactccagtt atcaaagtca tcgttgctgt gggacccagg actcgcaggc
    12841 cacttagaaa actgagaccc agggctgtct ccaggaccct cttgcccaga ccggagagat
    12901 gcttttttct tagcagcccg ccctcggctc ttagcaaatt tactgttgtt gtccatggac
    12961 gcagctcttc tccggggtga ttttccgctc ttgcctccct ctggattgag catccaccaa
    13021 gaactctttc cagttccttc attctgcact cgaataaact tgctgtgaag ggctagattg
    13081 cggcgaattg cattcttcca gcccgccgag ctgttgctgt cgcccttatc cttgaagtag
    13141 ggcacgctct tcaccatcca ctcgtagatc tgcgacaggg tgagcctctt ctcggctgag
    13201 ctctcgatgg ccttggtgat gaggtcggcg tacgacaggt tgccccacgc gttgcggcgc
    13261 gacgagctgg tcttgcgcgg ctgtcccgcg agtggccccg cggcggcggc agcggaggga
    13321 ggcacgggtg ggggctgcga cagcggcccg gtcggtgggg gctgtggcgg cgctgggtgc
    13381 acgcagcccg cctcggggcc ctggaagtcc ccgcacaggc ccctgctggc cgcagccgcc
    13441 gccgccacgg ccacgcagcc tggcgcccgc gcgaagtcct cactctcctc cagcaggctc
    13501 aggttgctca taaagtcggt gctgacagcg gacgccgagg ccaggctcgc cgcggcgtcg
    13561 gggttggcgg ccgcgccgcc cgacggcgcc ggactggagg tggtcgagtt ggactggtta
    13621 aactccggcc tgggcagcgg ccaggtacag gagcgctgcc ggggcagcgg ctcgaagtcc
    13681 gggtcggtct ccaccacctg gggagcctct gccatggtgg cgctagcttg ggctgcaggt
    13741 cgagggacct aataacttcg tatagcatac attatacgaa gttatattaa gggttccgga
    13801 tcagcttgat ggggatccag acatgataag atacattgat gagtttggac aaaccacaac
    13861 tagaatgcag tgaaaaaaat gctttatttg tgaaatttgt gatgctattg ctttatttgt
    13921 aaccattata agctgcaata aacaagttaa caacaacaat tgcattcatt ttatgtttca
    13981 ggttcagggg gaggtgtggg aggtttttta aagcaagtaa aacctctaca aatgtggtat
    14041 ggctgattat gatcctctag agtcgcagat ccagacatga taagatacat tgatgagttt
    14101 ggacaaacca caactagaat gcagtgaaaa aaatgcttta tttgtgaaat ttgtgatgct
    14161 attgctttat ttgtaaccat tataagctgc aataaacaag ttaacaacaa caattgcatt
    14221 cattttatgt ttcaggttca gggggaggtg tgggaggttt tttaaagcaa gtaaaacctc
    14281 tacaaatgtg gtatggctga ttatgatcct ctagagtcgc agatccagac atgataagat
    14341 acattgatga gtttggacaa accacaacta gaatgcagtg aaaaaaatgc tttatttgtg
    14401 aaatttgtga tgctattgct ttatttgtaa ccattataag ctgcaataaa caagttaaca
    14461 acaacaattg cattcatttt atgtttcagg ttcaggggga ggtgtgggag gttttttaaa
    14521 gcaagtaaaa cctctacaaa tgtggtatgg ctgattatga tcctctagag tcgcagatcc
    14581 tctagagtcg cagatctgca agcttctgat ggaattagaa cttggcaaaa caatactgag
    14641 aatgaagtgt atgtggaaca gaggctgctg atctcgttct tcaggctatg aaactgacac
    14701 atttggaaac cacagtactt agaaccacaa agtgggaatc aagagaaaaa caatgatccc
    14761 acgagagatc tatagatcta tagatcatga gtgggaggaa tgagctggcc cttaatttgg
    14821 ttttgcttgt ttaaattatg atatccaact atgaaacatt atcataaagc aatagtaaag
    14881 agccttcagt aaagagcagg catttatcta atcccacccc acccccaccc ccgtagctcc
    14941 aatccttcca ttcaaaatgt aggtactctg ttctcaccct tcttaacaaa gtatgacagg
    15001 aaaaacttcc attttagtgg acatctttat tgtttaatag atcatcaatt tctgcagact
    15061 tacagcggat cccctcagaa gaactcgtca agaaggcgat agaaggcgat gcgctgcgaa
    15121 tcgggagcgg cgataccgta aagcacgagg aagcggtcag cccattcgcc gccaagctct
    15181 tcagcaatat cacgggtagc caacgctatg tcctgatagc ggtccgccac acccagccgg
    15241 ccacagtcga tgaatccaga aaagcggcca ttttccacca tgatattcgg caagcaggca
    15301 tcgccatggg tcacgacgag atcatcgccg tcgggcatgc gcgccttgag cctggcgaac
    15361 agttcggctg gcgcgagccc ctgatgctct tcgtccagat catcctgatc gacaagaccg
    15421 gcttccatcc gagtacgtgc tcgctcgatg cgatgtttcg cttggtggtc gaatgggcag
    15481 gtagccggat caagcgtatg cagccgccgc attgcatcag ccatgatgga tactttctcg
    15541 gcaggagcaa ggtgagatga caggagatcc tgccccggca cttcgcccaa tagcagccag
    15601 tcccttcccg cttcagtgac aacgtcgagc acagctgcgc aaggaacgcc cgtcgtggcc
    15661 agccacgata gccgcgctgc ctcgtcctgc agttcattca gggcaccgga caggtcggtc
    15721 ttgacaaaaa gaaccgggcg cccctgcgct gacagccgga acacggcggc atcagagcag
    15781 ccgattgtct gttgtgccca gtcatagccg aatagcctct ccacccaagc ggccggagaa
    15841 cctgcgtgca atccatcttg ttcaatggcc gatcccatat tggctgcagg tcgaaaggcc
    15901 cggagatgag gaagaggaga acagcgcggc agacgtgcgc ttttgaagcg tgcagaatgc
    15961 cgggcctccg gaggaccttc gggcgcccgc cccgcccctg agcccgcccc tgagcccgcc
    16021 cccggaccca ccccttccca gcctctgagc ccagaaagcg aaggagcaaa gctgctattg
    16081 gccgctgccc caaaggccta cccgcttcca ttgctcagcg gtgctgtcca tctgcacgag
    16141 actagtgaga cgtgctactt ccatttgtca cgtcctgcac gacgcgagct gcggggcggg
    16201 gggggaactt cctgactagg ggaggagtag aaggtggcgc gaaggggcca ccaaagaacg
    16261 gagccggttg gcgcctaccg gtggatgtgg aatgtgtgcg aggccagagg ccacttgtgt
    16321 agcgccaagt gcccagcggg gctgctaaag cgcatgctcc agactgcctt gggaaaagcg
    16381 cctcccctac ccggtagaat tcctgcaggt cgagggacct aataacttcg tatagcatac
    16441 attatacgaa gttatattaa gggttccgga tccactagcc cgggggcgcg cccacgtgtt
    16501 cgaaactgga aagaccgcga agagtttgtc ctcaaccgcg agctgtggaa aaaaaaggga
    16561 caggataagt atgacatcat caaggaaacc ctggactact gcgccctacc tagaaagact
    16621 ggagttgcag atcacgaggg aagaggggga agggattctc ccaggcccag ggcggtcctc
    16681 agaagccagg aggcagcaga gaactcccag aaaggtattg caacactccc ctcccccctc
    16741 cggagaaggg tgcggccttc tccccgccta ctccactgca gctcccttac tgataacaac
    16801 tcagagcgac tttgggagag caagtgcttc ctgcctccaa aacagcccaa ctgagccctc
    16861 gctccttccc tccactcccc ggagtgcgcg atggaggtct ggctcagcac gcccctcttg
    16921 aggcaactca agtcggaaac gtgcttgcac ccgccccgca gccgctcagc cctactgccc
    16981 gtccccgccc ccagcgcgcg cttcctgcca cgttgcgcag gggcgcgcgg ccagactctg
    17041 cggcgcgggg ccgaggggag ggccggaacc tgggagcgcc tcctcgccgc ccccgctggc
    17101 cggcggatgg actcaacttg cacgaacacg agccaatggc aagggccagt tttctgggcc
    17161 ccgagagcca atcagacgac gaggcccggc cggcggcggg taaaacgact cccccagagg
    17221 aaggggaggg tgggcggccg ctcgcgcgcg agctactttc gctgaccctc cctcccctcc
    17281 cccgccccgc cagaggccga ccgcgcccgc acgtccagct cgcctcaccc cacctacctc
    17341 ccgccccacc cagtgggcag agcgaggctg ccggcggctg cgcactccgg ctgccgttaa
    17401 ctgacaggcg ccttacgcca accaaaacac gccatttgtg ttttcacaca cggcgggagg
    17461 aaaagaagcc aatcagcgac gagacgtcgg ccggaagcgc tcctccgctg cccccccccc
    17521 cccgagccat ggccgcgtcc ggtggagact tttccgctcc cttctccctc cccctccggt
    17581 tgctgcaggg cggaccgcat tcctgcccac cacccgcttg ccccttccag cgtcacgact
    17641 cgtacccggc tgtctcacag aacggctcca ccacgctcgg agggcctgcc gcggtggagc
    17701 tccaattcgc cctatagtga gtcgtattac gcgcgctcac tggccgtcgt tttacaacgt
    17761 cgtgactggg aaaaccctgg cgttacccaa cttaatcgcc ttgcagcaca tccccctttc
    17821 gccagctggc gtaatagcga agaggcccgc accgatcgcc cttcccaaca gttgcgcagc
    17881 ctgaatggcg aatggaaatt gtaagcgtta atattttgtt aaaattcgcg ttaaattttt
    17941 gttaaatcag ctcatttttt aaccaatagg ccgaaatcgg caaaatccct tataaatcaa
    18001 aagaatagac cgagataggg ttgagtgttg ttccagtttg gaacaagagt ccactattaa
    18061 agaacgtgga ctccaacgtc aaagggcgaa aaaccgtcta tcagggcgat ggcccactac
    18121 gtgaaccatc accctaatca agttttttgg ggtcgaggtg ccgtaaagca ctaaatcgga
    18181 accctaaagg gagcccccga tttagagctt gacggggaaa gccggcgaac gtggcgagaa
    18241 aggaagggaa gaaagcgaaa ggagcgggcg ctagggcgct ggcaagtgta gcggtcacgc
    18301 tgcgcgtaac caccacaccc gccgcgctta atgcgccgct acagggcgcg tcaggtggca
    18361 cttttcgggg aaatgtgcgc ggaaccccta tttgtttatt tttctaaata cattcaaata
    18421 tgtatccgct catgagacaa taaccctgat aaatgcttca ataatattga aaaaggaaga
    18481 gtatgagtat tcaacatttc cgtgtcgccc ttattccctt ttttgcggca ttttgccttc
    18541 ctgtttttgc tcacccagaa acgctggtga aagtaaaaga tgctgaagat cagtt
//
