LOCUS       pDBB63                 11404 bp ds-DNA     circular     30-OCT-2025
DEFINITION  .
COMMENT     Imported using the Genbank importer. File name: 56.final_pLann.gbk
            Annotated with pLannotate v1.2.2
FEATURES             Location/Qualifiers
     UAS             331..347
                     /label="GAL4 UAS"
                     /ApEinfo_revcolor="#f58a5e"
                     /ApEinfo_fwdcolor="#f58a5e"
     UAS             350..366
                     /label="GAL4 UAS"
                     /ApEinfo_revcolor="#f58a5e"
                     /ApEinfo_fwdcolor="#f58a5e"
     UAS             374..390
                     /label="GAL4 UAS"
                     /ApEinfo_revcolor="#f58a5e"
                     /ApEinfo_fwdcolor="#f58a5e"
     UAS             393..409
                     /label="GAL4 UAS"
                     /ApEinfo_revcolor="#f58a5e"
                     /ApEinfo_fwdcolor="#f58a5e"
     UAS             417..433
                     /label="GAL4 UAS"
                     /ApEinfo_revcolor="#f58a5e"
                     /ApEinfo_fwdcolor="#f58a5e"
     source          460..484
                     /label="source"
                     /ApEinfo_revcolor="#85dae9"
                     /ApEinfo_fwdcolor="#85dae9"
     misc_feature    460..484
                     /label="YB-TATA"
                     /ApEinfo_revcolor="#faac61"
                     /ApEinfo_fwdcolor="#faac61"
     CDS             554..2536
                     /ApEinfo_revcolor="#84b0dc"
                     /ApEinfo_fwdcolor="#84b0dc"
                     /translation="MLLLLARCFLVILASSLLVCPGLACGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAENSVAAKSGGSGSGSMCRAISLRRLLLLLLQLSQLLAVTQGKTLVLGKEGESAELPCESSQKKITVFTWKFSDQRKILGQHGKGVLIRGGSPSQFDRFDSKKGAWEKGSFPLIINKLKMEDSQTYICELENRKEEVELWVFKVTFSPGTSLLQGQSLTLTLDSNSKVSNPLTECKHKKGKVVSGSKVLSMSNLRVQDSDFWNCTVTLDQKKNWFGMTLSVLGFQSTAITAYKSEGESAEFSFPLNFAEENGWGELMWKAEKDSFFQPWISFSIKNKEVSVQKSTKDLKLQLKETLPLTLKIPQVSLQFAGSGNLTLTLDKGTLHQEVNLVVMKVAQLNNTLTCEVMGPTSPKMRLTLKQENQEARVSEEQKVVQVVAPETGLWQCLLSEGDKVKMDSRIQVLSRGVNQTVFLACVLGGSFGFLGFLGLCILCCVRCRHQQRQAARMSQIKRLLSEKKTCQCPHRMQKSHNLI*"
     misc_feature    555..1144
                     /label="SHH_N"
                     /ApEinfo_revcolor="#b4abac"
                     /ApEinfo_fwdcolor="#b4abac"
     exon            1162..1214
                     /label="Cd4-201 Exon 2"
                     /ApEinfo_revcolor="#c6c9d1"
                     /ApEinfo_fwdcolor="#c6c9d1"
     gene            1162..2536
                     /label="Cd4"
                     /ApEinfo_revcolor="#f58a5e"
                     /ApEinfo_fwdcolor="#f58a5e"
     exon            1215..1382
                     /label="Cd4-201 Exon 3"
                     /ApEinfo_revcolor="#b4abac"
                     /ApEinfo_fwdcolor="#b4abac"
     exon            1383..1544
                     /label="Cd4-201 Exon 4"
                     /ApEinfo_revcolor="#b4abac"
                     /ApEinfo_fwdcolor="#b4abac"
     exon            1545..1781
                     /label="Cd4-201 Exon 5"
                     /ApEinfo_revcolor="#84b0dc"
                     /ApEinfo_fwdcolor="#84b0dc"
     exon            1782..2117
                     /label="Cd4-201 Exon 6"
                     /ApEinfo_revcolor="#faac61"
                     /ApEinfo_fwdcolor="#faac61"
     exon            2118..2318
                     /label="Cd4-201 Exon 7"
                     /ApEinfo_revcolor="#ffef86"
                     /ApEinfo_fwdcolor="#ffef86"
     exon            2319..2437
                     /label="Cd4-201 Exon 8"
                     /ApEinfo_revcolor="#85dae9"
                     /ApEinfo_fwdcolor="#85dae9"
     exon            2438..2505
                     /label="Cd4-201 Exon 9"
                     /ApEinfo_revcolor="#d59687"
                     /ApEinfo_fwdcolor="#d59687"
     exon            2506..2536
                     /label="Cd4-201 Exon 10"
                     /ApEinfo_revcolor="#d59687"
                     /ApEinfo_fwdcolor="#d59687"
     misc_feature    complement(2537..2569)
                     /label="MCS (fragment)"
                     /ApEinfo_revcolor="#faac61"
                     /ApEinfo_fwdcolor="#faac61"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="100.0"
                     /match_length="30.6"
                     /fragment="True"
                     /other="misc_feature"
     misc_feature    2571..3156
                     /label="IRES2"
                     /ApEinfo_revcolor="#f58a5e"
                     /ApEinfo_fwdcolor="#f58a5e"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="99.8"
                     /match_length="100.0"
                     /fragment="False"
                     /other="misc_feature"
     CDS             3163..3540
                     /label="H2B"
                     /ApEinfo_revcolor="#84b0dc"
                     /ApEinfo_fwdcolor="#84b0dc"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="99.5"
                     /match_length="99.2"
                     /fragment="False"
                     /other="CDS"
                     /translation="MPEPAKSAPAPKKGSKKAVTKAQKKGGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAITKYTSAK"
     CDS             3559..4254
                     /label="mScarlet"
                     /ApEinfo_revcolor="#84b0dc"
                     /ApEinfo_fwdcolor="#84b0dc"
                     /note="pLannotate"
                     /database="fpbase"
                     /identity="99.6"
                     /match_length="100.0"
                     /fragment="False"
                     /other="CDS"
                     /translation="MVSKGEAVIKEFMRFKVHMEGSMNGHEFEIEGEGEGRPYEGTQTAKLKVTKGGPLPFSWDILSPQFMYGSRAFTKHPADIPDYYKQSFPEGFKWERVMNFEDGGAVTVTQDTSLEDGTLIYKVKLRGTNFPPDGPVMQKKTMGWEASTERLYPEDGVLKGDIKMALRLKDGGRYLADFKTTYKAKKPVQMPGAYNVDRNLDITSHNEDYTVVEQYERSEGRHSTGGMDELYK"
     promoter        complement(4276..4293)
                     /label="T7 promoter (fragment)"
                     /ApEinfo_revcolor="#b7e6d7"
                     /ApEinfo_fwdcolor="#b7e6d7"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="100.0"
                     /match_length="94.7"
                     /fragment="True"
                     /other="promoter"
     polyA_signal    complement(4298..4432)
                     /label="SV40 poly(A) signal"
                     /ApEinfo_revcolor="#b1ff67"
                     /ApEinfo_fwdcolor="#b1ff67"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="100.0"
                     /match_length="100.0"
                     /fragment="False"
                     /other="polyA_signal"
     promoter        4588..4799
                     /label="EF-1α core promoter"
                     /ApEinfo_revcolor="#f8d3a9"
                     /ApEinfo_fwdcolor="#f8d3a9"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="99.5"
                     /match_length="100.0"
                     /fragment="False"
                     /other="promoter"
     intron          4800..5738
                     /label="EF-1α intron A"
                     /ApEinfo_revcolor="#ff9ccd"
                     /ApEinfo_fwdcolor="#ff9ccd"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="100.0"
                     /match_length="100.0"
                     /fragment="False"
                     /other="intron"
     CDS             5757..6778
                     /label="HygR (fragment)"
                     /ApEinfo_revcolor="#84b0dc"
                     /ApEinfo_fwdcolor="#84b0dc"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="95.8"
                     /match_length="99.6"
                     /fragment="True"
                     /other="CDS"
                     /translation="MKKPELTATSVEKFLIEKFDSVSDLMQLSEGEESRAFSFDVGGRGYVLRVNSCADGFYKDRYVYRHFASAALPIPEVLDIGEFSESLTYCISRRAQGVTLQDLPETELPAVLQPVAEAMDAIAAADLSQTSGFGPFGPQGIGQYTTWRDFICAIADPHVYHWQTVMDDTVSASVAQALDELMLWAEDCPEVRHLVHADFGSNNVLTDNGRITAVIDWSEAMFGDSQYEVANIFFWRPWLACMEQQTRYFERRHPELAGSPRLRAYMLRIGLDQLYQSLVDGNFDDAAWAQGRCDAIVRSGAGTVGRTQIARRSAAVWTDGCVEVLADSGNRRPSTRPRAK"
     misc_feature    6795..6901
                     /label="WPRE (fragment)"
                     /ApEinfo_revcolor="#85dae9"
                     /ApEinfo_fwdcolor="#85dae9"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="96.3"
                     /match_length="26.5"
                     /fragment="True"
                     /other="misc_feature"
     polyA_signal    6910..7031
                     /label="SV40 poly(A) signal"
                     /ApEinfo_revcolor="#9eafd2"
                     /ApEinfo_fwdcolor="#9eafd2"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="100.0"
                     /match_length="100.0"
                     /fragment="False"
                     /other="polyA_signal"
     ncRNA           7049..7141
                     /label="G-CSF SLDE"
                     /ApEinfo_revcolor="#d59687"
                     /ApEinfo_fwdcolor="#d59687"
                     /note="pLannotate"
                     /database="Rfam"
                     /identity="100.0"
                     /match_length="96.9"
                     /fragment="False"
                     /other="ncRNA"
     CDS             7838..8305
                     /label="B (fragment)"
                     /ApEinfo_revcolor="#84b0dc"
                     /ApEinfo_fwdcolor="#84b0dc"
                     /note="pLannotate"
                     /database="swissprot"
                     /identity="100.0"
                     /match_length="29.3"
                     /fragment="True"
                     /other="CDS"
                     /translation="LHQDHIVGSFFRLSHRPSWRYLGIGEEEARAFSREVEAAWKEFAEDDCCCIDVERKRTFTMMIREGVAMHAFNGELFVQATWDTSSSRLFRTQFRMVSPKRISNPNNTGDSRNCRAGVQINDSGAALGYYVSEDGYPGWMPQKWTWIPRELPGGRA"
     protein_bind    complement(8341..8363)
                     /label="lac operator (fragment)"
                     /ApEinfo_revcolor="#d6b295"
                     /ApEinfo_fwdcolor="#d6b295"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="100.0"
                     /match_length="92.0"
                     /fragment="True"
                     /other="protein_bind"
     promoter        complement(8367..8397)
                     /label="lac promoter"
                     /ApEinfo_revcolor="#75c6a9"
                     /ApEinfo_fwdcolor="#75c6a9"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="100.0"
                     /match_length="100.0"
                     /fragment="False"
                     /other="promoter"
     protein_bind    complement(8412..8433)
                     /label="CAP binding site"
                     /ApEinfo_revcolor="#85dae9"
                     /ApEinfo_fwdcolor="#85dae9"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="100.0"
                     /match_length="100.0"
                     /fragment="False"
                     /other="protein_bind"
     CDS             complement(8446..8538)
                     /label="lacI (fragment)"
                     /ApEinfo_revcolor="#84b0dc"
                     /ApEinfo_fwdcolor="#84b0dc"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="100.0"
                     /match_length="8.6"
                     /fragment="True"
                     /other="CDS"
                     /translation="APNTQTASPRALADSLMQLARQVSRLESGQ*"
     rep_origin      complement(8721..9309)
                     /label="ori"
                     /ApEinfo_revcolor="#b4abac"
                     /ApEinfo_fwdcolor="#b4abac"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="99.8"
                     /match_length="100.0"
                     /fragment="False"
                     /other="rep_origin"
     CDS             complement(9480..10340)
                     /label="AmpR"
                     /ApEinfo_revcolor="#84b0dc"
                     /ApEinfo_fwdcolor="#84b0dc"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="99.8"
                     /match_length="100.0"
                     /fragment="False"
                     /other="CDS"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW*"
     promoter        complement(10341..10445)
                     /label="AmpR promoter"
                     /ApEinfo_revcolor="#ffef86"
                     /ApEinfo_fwdcolor="#ffef86"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="100.0"
                     /match_length="100.0"
                     /fragment="False"
                     /other="promoter"
     rep_origin      complement(10498..10926)
                     /label="f1 ori"
                     /ApEinfo_revcolor="#75c6a9"
                     /ApEinfo_fwdcolor="#75c6a9"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="100.0"
                     /match_length="100.0"
                     /fragment="False"
                     /other="rep_origin"
     CDS             complement(10931..11086)
                     /label="lacZα (fragment)"
                     /ApEinfo_revcolor="#84b0dc"
                     /ApEinfo_fwdcolor="#84b0dc"
                     /note="pLannotate"
                     /database="snapgene"
                     /identity="100.0"
                     /match_length="89.7"
                     /fragment="True"
                     /other="CDS"
                     /translation="SLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGE"
     CDS             11088..11207
                     /label="B (fragment)"
                     /ApEinfo_revcolor="#84b0dc"
                     /ApEinfo_fwdcolor="#84b0dc"
                     /note="pLannotate"
                     /database="swissprot"
                     /identity="100.0"
                     /match_length="7.5"
                     /fragment="True"
                     /other="CDS"
                     /translation="RASFIHVFEPVEDGQTRGANVFYSVMEQMKMLDTLQNTQL"
ORIGIN
        1 aaaaacaaaa actcaaaatt tcttctataa agtaacaaaa cttttatgag ggacagcccc
       61 cccccaaagc ccccagggat gtaattacgt ccctcccccg ctagggggca gcagcgagcc
      121 gcccggggct ccgctccggt ccggcgctcc ccccgcatcc ccgagccggc agcgtgcggg
      181 gacagcccgg gcacggggaa ggtggcacgg gatcgctttc ctctgaacgc ttctcgctgc
      241 tctttgagcc tgcagacacc tggggggata cggggaaaag gcctccacgg ccactagtaa
      301 acgcggccac tagtaaacgg agtttctaga CGGAGTACTG TCCTCCGagC GGAGTACTGT
      361 CCTCCGactc gagCGGAGTA CTGTCCTCCG atCGGAGTAC TGTCCTCCGc gaattcCGGA
      421 GTACTGTCCT CCGaagacgc tagcgggcga tccatatgct ctagagggta tataatgggg
      481 gccactagtc tactaccaga aagcttggca ttccggtact gggtaaagcc gaattcctag
      541 cgccgccacc accatgctgc tgctgctggc cagatgtttt ctggtgatcc ttgcttcctc
      601 gctgctggtg tgccccgggc tggcctgtgg gcccggcagg gggtttggaa agaggcggca
      661 ccccaaaaag ctgacccctt tagcctacaa gcagtttatt cccaacgtag ccgagaagac
      721 cctaggggcc agcggcagat atgaagggaa gatcacaaga aactccgaac gatttaagga
      781 actcaccccc aattacaacc ccgacatcat atttaaggat gaggaaaaca cgggagcaga
      841 ccggctgatg actcagaggt gcaaagacaa gttaaatgcc ttggccatct ctgtgatgaa
      901 ccagtggcct ggagtgaagc tgcgagtgac cgagggctgg gatgaggacg gccatcattc
      961 agaggagtct ctacactatg agggtcgagc agtggacatc accacgtccg accgggaccg
     1021 cagcaagtac ggcatgctgg ctcgcctggc tgtggaagca ggtttcgact gggtctacta
     1081 tgaatccaaa gctcacatcc actgttctgt gaaagcagag aactccgtgg cggccaaatc
     1141 cggcGGTAgc ggcagcggta gcATGTGCCG AGCCATCTCT CTTAGGCGCT tgctgctgct
     1201 gctgctgcAG CTGTCACAAC TCCTAGCTGT CACTCAAGGG AAGACGCTGG TGCTGGGGAA
     1261 GGAAGGGGAA TCAGCAGAAC TGCCCTGCGA GAGTTCCCAG AAGAAGATCA CAGTCTTCAC
     1321 CTGGAAGTTC TCTGACCAGA GGAAGATTCT GGGGCAGCAT GGCAAAGGTG TATTAATTAG
     1381 AGGAGGTTCG CCTTCGCAGT TTGATCGTTT TGATTCCAAA AAAGGGGCAT GGGAGAAAGG
     1441 ATCGTTTCCT CTCATCATCA ATAAACTTAA GATGGAAGAC TCTCAGACTT ATATCTGTGA
     1501 GCTGGAGAAC AGGAAAGAGG AGGTGGAGTT GTGGGTGTTC AAAGTGACCT TCAGTCCGGG
     1561 TACCAGCCTG TTGCAAGGGC AGAGCCTGAC CCTGACCTTG GATAGCAACT CTAAGGTCTC
     1621 TAACCCCTTG ACAGAGTGCA AACACAAAAA GGGTAAAGTT GTCAGTGGTT CCAAAGTTCT
     1681 CTCCATGTCC AACCTAAGGG TTCAGGACAG CGACTTCTGG AACTGCACCG TGACCCTGGA
     1741 CCAGAAAAAG AACTGGTTCG GCATGACACT CTCAGTGCTG GGTTTTCAGA GCACAGCTAT
     1801 CACGGCCTAT AAGAGTGAGG GAGAGTCAGC GGAGTTCTCC TTCCCACTCA ACTTTGCAGA
     1861 GGAAAACGGG TGGGGAGAGC TGATGTGGAA GGCAGAGAAG GATTCTTTCT TCCAGCCCTG
     1921 GATCTCCTTC TCCATAAAGA ACAAAGAGGT GTCCGTACAA AAGTCCACCA AAGACCTCAA
     1981 GCTCCAGCTG AAGGAAACGC TCCCACTCAC CCTCAAGATA CCCCAGGTCT CGCTTCAGTT
     2041 TGCTGGTTCT GGCAACCTGA CTCTGACTCT GGACAAAGGG ACACTGCATC AGGAAGTGAA
     2101 CCTGGTGGTG ATGAAAGTGG CTCAGCTCAA CAATACTTTG ACCTGTGAGG TGATGGGACC
     2161 TACCTCTCCC AAGATGAGAC TGACCCTGAA GCAGGAGAAC CAGGAGGCCA GGGTCTCTGA
     2221 GGAGCAGAAA GTAGTTCAAG TGGTGGCCCC TGAGACAGGG CTGTGGCAGT GTCTACTGAG
     2281 TGAAGGTGAT AAGGTCAAGA TGGACTCCAG GATCCAGGTT TTATCCAGAG GGGTGAACCA
     2341 GACAGTGTTC CTGGCTTGCG TGCTGGGTGG CTCCTTCGGC TTTCTGGGTT TCCTTGGGCT
     2401 CTGCATCCTC TGCTGTGTCA GGTGCCGGCA CCAACAGCGC CAGGCAGCAC GAATGTCTCA
     2461 GATCAAGAGG CTCCTCAGTG AGAAGAAGAC CTGCCAGTGC CCCCACCGGA TGCAGAAGAG
     2521 CCATAATCTC ATCTGActtg atatcgaatt cctgcagccc gggggatccg cccctctccc
     2581 tccccccccc taacgttact ggccgaagcc gcttggaata aggccggtgt gcgtttgtct
     2641 atatgttatt ttccaccata ttgccgtctt ttggcaatgt gagggcccgg aaacctggcc
     2701 ctgtcttctt gacgagcatt cctaggggtc tttcccctct cgccaaagga atgcaaggtc
     2761 tgttgaatgt cgtgaaggaa gcagttcctc tggaagcttc ttgaagacaa acaacgtctg
     2821 tagcgaccct ttgcaggcag cggaaccccc cacctggcga caggtgcctc tgcggccaaa
     2881 agccacgtgt ataagataca cctgcaaagg cggcacaacc ccagtgccac gttgtgagtt
     2941 ggatagttgt ggaaagagtc aaatggctct cctcaagcgt attcaacaag gggctgaagg
     3001 atgcccagaa ggtaccccat tgtatgggat ctgatctggg gcctcggtac acatgcttta
     3061 catgtgttta gtcgaggtta aaaaaacgtc taggcccccc gaaccacggg gacgtggttt
     3121 tcctttgaaa aacacgatga taatatggcc acaaccatgg ttatgccaga gccagcgaag
     3181 tctgctcccg ccccgaaaaa gggctccaag aaggcggtga ctaaggcgca gaagaaaggc
     3241 ggcaagaagc gcaagcgcag ccgcaaggag agctattcca tctatgtgta caaggttctg
     3301 aagcaggtcc accctgacac cggcatttcg tccaaggcca tgggcatcat gaattcgttt
     3361 gtgaacgaca ttttcgagcg catcgcaggt gaggcttccc gcctggcgca ttacaacaag
     3421 cgctcgacca tcacctccag ggagatccag acggccgtgc gcctgctgct gcctggggag
     3481 ttggccaagc acgccgtgtc cgagggtact aaggccatca ccaagtacac cagcgctaag
     3541 gatccaccgg tcgccaccat ggtatcaaaa ggcgaggcgg tcattaaaga gttcatgagg
     3601 tttaaagtcc atatggaagg aagcatgaat ggtcacgagt ttgagataga gggagagggt
     3661 gagggaaggc cgtacgaagg gacgcaaact gcgaagttga aggtaacgaa aggcggccct
     3721 ctgccattct cttgggacat cctttcaccg caatttatgt acggctctag ggccttcaca
     3781 aaacaccccg ccgatattcc ggattactat aaacaaagtt ttcctgaggg cttcaagtgg
     3841 gaaagagtaa tgaacttcga ggatggggga gctgtgacgg ttactcaaga cactagcctg
     3901 gaggacggta ctcttatata caaggtaaaa ctaagaggga cgaattttcc gccagacggc
     3961 cccgtgatgc aaaaaaaaac tatggggtgg gaagcatcca ccgagaggct gtaccccgaa
     4021 gacggggtcc tgaagggtga tattaaaatg gcattaagat taaaagatgg cgggagatac
     4081 ttagctgact tcaagactac atataaagcc aaaaaacctg tacagatgcc tggagcttac
     4141 aatgtggatc gtaatctgga tattacatcc cacaacgaag attataccgt ggtggagcag
     4201 tacgagcgtt cagaggggcg tcactccacc gggggtatgg atgaattata caagtaagat
     4261 ttcgagcctc tagaactata gtgagtcgta ttacgtagat ccagacatga taagatacat
     4321 tgatgagttt ggacaaacca caactagaat gcagtgaaaa aaatgcttta tttgtgaaat
     4381 ttgtgatgct attgctttat ttgtaaccat tataagctgc aataaacaag ttaacaacaa
     4441 caattgcatt cattttatgt ttcaggttca gggggaggtg tgggaggttt tttaattcgc
     4501 tgggatccga tttaaattcg aattcgggcc cgcggccgca ctcaattctc tagaaatatt
     4561 ctcgaggttt ctccggtgcc cgtcagtggg cagagcgcac atcgcccaca gtccccgaga
     4621 agttgggggg aggggtcggc aattgaaccg gtgcctagag aaggtggcgc ggggtaaact
     4681 gggaaagtga tgtcgtgtac tggctccgcc tttttcccga gggtggggga gaaccgtata
     4741 taagtgcagt agtcgccgtg aacgttcttt ttcgcaacgg gtttgccgcc agaacacagg
     4801 taagtgccgt gtgtggttcc cgcgggcctg gcctctttac gggttatggc ccttgcgtgc
     4861 cttgaattac ttccacctgg ctgcagtacg tgattcttga tcccgagctt cgggttggaa
     4921 gtgggtggga gagttcgagg ccttgcgctt aaggagcccc ttcgcctcgt gcttgagttg
     4981 aggcctggcc tgggcgctgg ggccgccgcg tgcgaatctg gtggcacctt cgcgcctgtc
     5041 tcgctgcttt cgataagtct ctagccattt aaaatttttg atgacctgct gcgacgcttt
     5101 ttttctggca agatagtctt gtaaatgcgg gccaagatct gcacactggt atttcggttt
     5161 ttggggccgc gggcggcgac ggggcccgtg cgtcccagcg cacatgttcg gcgaggcggg
     5221 gcctgcgagc gcggccaccg agaatcggac gggggtagtc tcaagctggc cggcctgctc
     5281 tggtgcctgg cctcgcgccg ccgtgtatcg ccccgccctg ggcggcaagg ctggcccggt
     5341 cggcaccagt tgcgtgagcg gaaagatggc cgcttcccgg ccctgctgca gggagctcaa
     5401 aatggaggac gcggcgctcg ggagagcggg cgggtgagtc acccacacaa aggaaaaggg
     5461 cctttccgtc ctcagccgtc gcttcatgtg actccacgga gtaccgggcg ccgtccaggc
     5521 acctcgatta gttctcgagc ttttggagta cgtcgtcttt aggttggggg gaggggtttt
     5581 atgcgatgga gtttccccac actgagtggg tggagactga agttaggcca gcttggcact
     5641 tgatgtaatt ctccttggaa tttgcccttt ttgagtttgg atcttggttc attctcaagc
     5701 ctcagacagt ggttcaaagt ttttttcttc catttcaggt gtcgtgaggc gccaccatga
     5761 aaaagcctga actcaccgct acctctgtcg agaagtttct gatcgaaaag ttcgacagcg
     5821 tgtccgacct gatgcagctc tccgagggcg aagaatctcg ggctttcagc ttcgatgtgg
     5881 gagggcgtgg atatgtcctg cgggtgaata gctgcgccga tggtttctac aaagatcgct
     5941 atgtttatcg gcactttgca tccgccgctc tccctattcc cgaagtgctt gacattgggg
     6001 agttcagcga gagcctgacc tattgcatct cccgccgtgc acagggtgtc accttgcaag
     6061 acctgcctga aaccgaactg cccgctgttc tccagcccgt cgccgaggcc atggatgcca
     6121 tcgctgccgc cgatcttagc cagaccagcg ggttcggccc attcggacct caaggaatcg
     6181 gtcaatacac tacatggcgc gatttcatct gcgctattgc tgatccccat gtgtatcact
     6241 ggcaaactgt gatggacgac accgtcagtg cctccgtcgc ccaggctctc gatgagctga
     6301 tgctttgggc cgaggactgc cccgaagtcc ggcacctcgt gcacgccgat ttcggctcca
     6361 acaatgtcct gaccgacaat ggccgcataa cagccgtcat tgactggagc gaggccatgt
     6421 tcggggattc ccaatacgag gtcgccaaca tcttcttctg gaggccctgg ttggcttgta
     6481 tggagcagca gacccgctac ttcgagcgga ggcatcccga gcttgcagga tctcctcggc
     6541 tccgggctta tatgctccgc attggtcttg accaactcta tcagagcttg gttgacggca
     6601 atttcgatga tgcagcttgg gctcagggtc gctgcgacgc aatcgtccgg tccggagccg
     6661 ggactgtcgg gcgtacacaa atcgcccgca gaagcgctgc cgtctggacc gatggctgtg
     6721 tggaagtgct cgccgatagt ggaaacagac gccccagcac tcgtcctagg gcaaaggatc
     6781 tgcagtaagt cgacaatcaa cctctggatt acaaaatttg tgaaagattg actggtattc
     6841 ttaactatgt tgctcctttt acgctatgtg gatacgctgc tttaatgcct ttgtatcatg
     6901 cgttaactaa acttgtttat tgcagcttat aatggttaca aataaagcaa tagcatcaca
     6961 aatttcacaa ataaagcatt tttttcactg cattctagtt gtggtttgtc caaactcatc
     7021 aatgtatctt atcatgtctg gaattgactc aaatgatgtc aattagtcta tcagaagctc
     7081 atctggtctc ccttccgggg gacaagacat ccctgtttaa tatttaaaca gcagtgttcc
     7141 caaactgggt tcttatatcc cttgctctgg tcaaccaggt tgcagggttt cctgtcctca
     7201 caggaacgaa gtccctaaag aaacagtggc agccaggttt agccccggaa ttgactggat
     7261 tcctttttta gggcccattg gtatggcttt ttccccgtat ccccccaggt gtctgcaggc
     7321 tcaaagagca gcgagaagcg ttcagaggaa agcgatcccg tgccaccttc cccgtgcccg
     7381 ggctgtcccc gcacgctgcc ggctcgggga tgcgggggga gcgccggacc ggagcggagc
     7441 cccgggcggc tcgctgctgc cccctagcgg gggagggacg taattacatc cctgggggct
     7501 ttgggggggg gctgtccctg atatctataa caagaaaata tatatataat aagttatcac
     7561 gtaagtagaa catgaaataa caatataatt atcgtatgag ttaaatctta aaagtcacgt
     7621 aaaagataat catgcgtcat tttgactcac gcggtcgtta tagttcaaaa tcagtgacac
     7681 ttaccgcatt gacaagcacg cctcacggga gctccaagcg gcgactgaga tgtcctaaat
     7741 gcacagcgac ggattcgcgc tatttagaaa gagagagcaa tatttcaaga atgcatgcgt
     7801 caattttacg cagactatct ttctagggtt aatctagctg catcaggatc atatcgtcgg
     7861 gtcttttttc cggctcagtc atcgcccaag ctggcgctat ctgggcatcg gggaggaaga
     7921 agcccgtgcc ttttcccgcg aggttgaagc ggcatggaaa gagtttgccg aggatgactg
     7981 ctgctgcatt gacgttgagc gaaaacgcac gtttaccatg atgattcggg aaggtgtggc
     8041 catgcacgcc tttaacggtg aactgttcgt tcaggccacc tgggatacca gttcgtcgcg
     8101 gcttttccgg acacagttcc ggatggtcag cccgaagcgc atcagcaacc cgaacaatac
     8161 cggcgacagc cggaactgcc gtgccggtgt gcagattaat gacagcggtg cggcgctggg
     8221 atattacgtc agcgaggacg ggtatcctgg ctggatgccg cagaaatgga catggatacc
     8281 ccgtgagtta cccggcgggc gcgcttggcg taatcatggt catagctgtt tcctgtgtga
     8341 aattgttatc cgctcacaat tccacacaac atacgagccg gaagcataaa gtgtaaagcc
     8401 tggggtgcct aatgagtgag ctaactcaca ttaattgcgt tgcgctcact gcccgctttc
     8461 cagtcgggaa acctgtcgtg ccagctgcat taatgaatcg gccaacgcgc ggggagaggc
     8521 ggtttgcgta ttgggcgctc ttccgcttcc tcgctcactg actcgctgcg ctcggtcgtt
     8581 cggctgcggc gagcggtatc agctcactca aaggcggtaa tacggttatc cacagaatca
     8641 ggggataacg caggaaagaa catgtgagca aaaggccagc aaaaggccag gaaccgtaaa
     8701 aaggccgcgt tgctggcgtt tttccatagg ctccgccccc ctgacgagca tcacaaaaat
     8761 cgacgctcaa gtcagaggtg gcgaaacccg acaggactat aaagatacca ggcgtttccc
     8821 cctggaagct ccctcgtgcg ctctcctgtt ccgaccctgc cgcttaccgg atacctgtcc
     8881 gcctttctcc cttcgggaag cgtggcgctt tctcatagct cacgctgtag gtatctcagt
     8941 tcggtgtagg tcgttcgctc caagctgggc tgtgtgcacg aaccccccgt tcagcccgac
     9001 cgctgcgcct tatccggtaa ctatcgtctt gagtccaacc cggtaagaca cgacttatcg
     9061 ccactggcag cagccactgg taacaggatt agcagagcga ggtatgtagg cggtgctaca
     9121 gagttcttga agtggtggcc taactacggc tacactagaa gaacagtatt tggtatctgc
     9181 gctctgctga agccagttac cttcggaaaa agagttggta gctcttgatc cggcaaacaa
     9241 accaccgctg gtagcggtgg tttttttgtt tgcaagcagc agattacgcg cagaaaaaaa
     9301 ggatctcaag aagatccttt gatcttttct acggggtctg acgctcagtg gaacgaaaac
     9361 tcacgttaag ggattttggt catgagatta tcaaaaagga tcttcaccta gatcctttta
     9421 aattaaaaat gaagttttaa atcaatctaa agtatatatg agtaaacttg gtctgacagt
     9481 taccaatgct taatcagtga ggcacctatc tcagcgatct gtctatttcg ttcatccata
     9541 gttgcctgac tccccgtcgt gtagataact acgatacggg agggcttacc atctggcccc
     9601 agtgctgcaa tgataccgcg agacccacgc tcaccggctc cagatttatc agcaataaac
     9661 cagccagccg gaagggccga gcgcagaagt ggtcctgcaa ctttatccgc ctccatccag
     9721 tctattaatt gttgccggga agctagagta agtagttcgc cagttaatag tttgcgcaac
     9781 gttgttgcca ttgctacagg catcgtggtg tcacgctcgt cgtttggtat ggcttcattc
     9841 agctccggtt cccaacgatc aaggcgagtt acatgatccc ccatgttgtg caaaaaagcg
     9901 gttagctcct tcggtcctcc gatcgttgtc agaagtaagt tggccgcagt gttatcactc
     9961 atggttatgg cagcactgca taattctctt actgtcatgc catccgtaag atgcttttct
    10021 gtgactggtg agtactcaac caagtcattc tgagaatagt gtatgcggcg accgagttgc
    10081 tcttgcccgg cgtcaatacg ggataatacc gcgccacata gcagaacttt aaaagtgctc
    10141 atcattggaa aacgttcttc ggggcgaaaa ctctcaagga tcttaccgct gttgagatcc
    10201 agttcgatgt aacccactcg tgcacccaac tgatcttcag catcttttac tttcaccagc
    10261 gtttctgggt gagcaaaaac aggaaggcaa aatgccgcaa aaaagggaat aagggcgaca
    10321 cggaaatgtt gaatactcat actcttcctt tttcaatatt attgaagcat ttatcagggt
    10381 tattgtctca tgagcggata catatttgaa tgtatttaga aaaataaaca aataggggtt
    10441 ccgcgcacat ttccccgaaa agtgccacct aaattgtaag cgttaatatt ttgttaaaat
    10501 tcgcgttaaa tttttgttaa atcagctcat tttttaacca ataggccgaa atcggcaaaa
    10561 tcccttataa atcaaaagaa tagaccgaga tagggttgag tgttgttcca gtttggaaca
    10621 agagtccact attaaagaac gtggactcca acgtcaaagg gcgaaaaacc gtctatcagg
    10681 gcgatggccc actacgtgaa ccatcaccct aatcaagttt tttggggtcg aggtgccgta
    10741 aagcactaaa tcggaaccct aaagggagcc cccgatttag agcttgacgg ggaaagccgg
    10801 cgaacgtggc gagaaaggaa gggaagaaag cgaaaggagc gggcgctagg gcgctggcaa
    10861 gtgtagcggt cacgctgcgc gtaaccacca cacccgccgc gcttaatgcg ccgctacagg
    10921 gcgcgtccca ttcgccattc aggctgcgca actgttggga agggcgatcg gtgcgggcct
    10981 cttcgctatt acgccagctg gcgaaagggg gatgtgctgc aaggcgatta agttgggtaa
    11041 cgccagggtt ttcccagtca cgacgttgta aaacgacggc cagtgagcgc gcctcgttca
    11101 ttcacgtttt tgaacccgtg gaggacgggc agactcgcgg tgcaaatgtg ttttacagcg
    11161 tgatggagca gatgaagatg ctcgacacgc tgcagaacac gcagctagat taaccctaga
    11221 aagataatca tattgtgacg tacgttaaag ataatcatgt gtaaaattga cgcatgtgtt
    11281 ttatcggtct gtatatcgag gtttatttat taatttgaat agatattaag ttttattata
    11341 tttacactta catactaata ataaattcaa caaacaattt atttatgttt atttatttat
    11401 taaa
//