LOCUS       sequence-133065-         812 bp    DNA     linear   UNA 14-APR-2025
DEFINITION  encodes Progerin with a substitution of cysteine in CaaX-motif by a 
            serine.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 812)
  AUTHORS   Moiseeva O, Lessard F, Acevedo-Aquino M, Vernier M, Tsantrizos YS, 
            Ferbeyre G
  TITLE     Mutant lamin A links prophase to a p53 independent senescence 
            program.
  JOURNAL   Cell Cycle. 2015 Aug 3;14(15):2408-21. doi: 
            10.1080/15384101.2015.1053671. Epub 2015 Jun 1.
  PUBMED    26029982
REFERENCE   2  (bases 1 to 812)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Apr 14, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1080/15384101.2015.1053671"; journalName: "Cell Cycle"; date: 
            "2015-08-3- 3"; volume: "14"; issue: "15"; pages: "2408-21"
COMMENT     Sequence Label: pLPC-Progerin-CS
FEATURES             Location/Qualifiers
     source          1..812
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     primer_bind     23..42
                     /label=T7
                     /note="T7 promoter, forward primer"
     promoter        23..41
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
ORIGIN
        1 ctgcttactg gcttatcgaa attaatacga ctcactatag ggagacccaa gcttggtacc
       61 gagctcggat ccaccatgga gaccccgtcc cagcggcgcg ccacccgcag cggggcgcag
      121 gccagctcca ctccgctgtc gcccacccgc atcacccggc tgcaggagaa ggaggacctg
      181 caggagctca atgatcgctt ggcggtctac atcgaccgtg tgcgctcgct ggaaacggag
      241 aacgcagggc tgcgccttcg catcaccgag tctgaagagg tggtcagccg cgaggtgtcc
      301 ggcatcaagg ccgcctacga ggccgagctc ggggatgccc gcaagaccct tgactcagta
      361 gccaaggagc gcgcccgcct gcagctggag ctgagcaaag tgcgtgagga gtttaaggag
      421 ctgaaagcgc gcaataccaa gaaggagggt gacctgatag ctgctcaggc tcggctgaag
      481 gacctggagg ctctgctgaa ctccaaggag gccgcactga gcactgctct cagtgagaag
      541 cgcacgctgg agggcgagct gcatgatctg cggggccagg tggccaagct tgaggcagcc
      601 ctaggtgagg ccaagaagca acttcaggat gagatgctgc ggcgggtgga tgctgagaac
      661 aggctgcaga ccatgaagga ggaactggac ttccagaaga acatctacag tgaggagctg
      721 cgtgagacca agcgccgtca tgagacccga ctggtggaga ttgacaatgg gaagcagcgt
      781 gagtttgaga gccggctggc ggatgcgctg ca
//
