LOCUS       sequence-203194-       13354 bp    DNA     linear   UNA 15-APR-2025
DEFINITION  targeting vector to generate a Gucy1b2-IRES-nlsCre-IRES-taulacZ 
            mouse strain..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 13354)
  AUTHORS   Koike K, Yoo SJ, Bleymehl K, Omura M, Zapiec B, Pyrski M, Blum T, 
            Khan M, Bai Z, Leinders-Zufall T, Mombaerts P, Zufall F
  TITLE     Danger perception and stress response through an olfactory sensor 
            for the bacterial metabolite hydrogen sulfide.
  JOURNAL   Neuron. 2021 Aug 4;109(15):2469-2484.e7. doi: 
            10.1016/j.neuron.2021.05.032. Epub 2021 Jun 28.
  PUBMED    34186026
REFERENCE   2  (bases 1 to 13354)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Apr 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1016/j.neuron.2021.05.032"; journalName: "Neuron"; date: 
            "2021-08-4- 4"; volume: "109"; issue: "15"; pages: "2469-2484.e7"
COMMENT     Sequence Label: Gucy1b2-IRES-nlsCre-IRES-taulacZ-FNF TV
FEATURES             Location/Qualifiers
     source          1..13354
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     misc_feature    13..564
                     /label=IRES
                     /note="internal ribosome entry site (IRES) of the 
                     encephalomyocarditis virus (EMCV)"
     primer_bind     complement(157..174)
                     /label=IRES reverse
                     /note="IRES internal ribosome entry site, reverse primer. 
                     Also called pCDH-rev"
     CDS             1734..4781
                     /codon_start=1
                     /gene="lacZ"
                     /product="beta-galactosidase"
                     /label=lacZ
                     /translation="VVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRS
                     LNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYTNVTYPITVNPP
                     FVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEF
                     DLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFHVATR
                     FNDDFSRAVLEAEVQMCGELRDYLRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRV
                     TLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEACDVGFREVRIENGLLLLNGKP
                     LLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGL
                     YVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGA
                     NHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVDEDQPFPAVPKWSIKKWLS
                     LPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGGFVWDWVDQSLIKYDENGNP
                     WSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFRLSGQTIEVTSEYL
                     FRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIELPELPQPESAGQLWLTVRVVQ
                     PNATAWSEAGHISAWQQWRLAENLSVTLPAASHAIPHLTTSEMDFCIELGNKRWQFNRQ
                     SGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEATRIDPNAWVERWKAAGHYQAEA
                     ALLQCTADTLADAVLITTAHAWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASDTPHP
                     ARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLR
                     CGTRELNYGPHQWRGDFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDD
                     SWSPSVSAEFQLSAGRYHYQLVWCQK"
     primer_bind     complement(1736..1758)
                     /label=M13/pUC Forward
                     /note="In lacZ gene"
     protein_bind    4819..4866
                     /label=FRT
                     /bound_moiety="FLP recombinase from the Saccharomyces 
                     cerevisiae 2u plasmid"
                     /note="FLP-mediated recombination occurs in the 8-bp core 
                     sequence TCTAGAAA (Turan and Bode, 2011)."
     promoter        4897..5396
                     /label=PGK promoter
                     /note="mouse phosphoglycerate kinase 1 promoter"
     primer_bind     complement(4932..4955)
                     /label=MSCV-rev
                     /note="Murine stem cell virus, reverse primer"
     primer_bind     5329..5348
                     /label=mPGK-F
                     /note="Mouse PGK promoter, forward primer"
     CDS             5410..6213
                     /codon_start=1
                     /gene="aph(3')-II (or nptII)"
                     /product="aminoglycoside phosphotransferase from Tn5"
                     /label=NeoR/KanR
                     /note="confers resistance to neomycin, kanamycin, and G418 
                     (Geneticin(R))"
                     /translation="MGSAIEQDGLHAGSPAAWVERLFGYDWAQQTIGCSDAAVFRLSAQ
                     GRPVLFVKTDLSGALNELQDEAARLSWLATTGVPCAAVLDVVTEAGRDWLLLGEVPGQD
                     LLSSHLAPAEKVSIMADAMRRLHTLDPATCPFDHQAKHRIERARTRMEAGLVDQDDLDE
                     EHQGLAPAELFARLKARMPDGDDLVVTHGDACLPNIMVENGRFSGFIDCGRLGVADRYQ
                     DIALATRDIAEELGGEWADRFLVLYGIAAPDSQRIAFYRLLDEFF"
     primer_bind     complement(5473..5492)
                     /label=Neo-R
                     /note="Neomycin resistance gene, reverse primer"
     primer_bind     6083..6102
                     /label=Neo-F
                     /note="Neomycin resistance gene, forward primer"
     polyA_signal    6223..6684
                     /label=PGK poly(A) signal
                     /note="mouse phosphoglycerate kinase 1 polyadenylation 
                     signal"
     protein_bind    6711..6758
                     /label=FRT
                     /bound_moiety="FLP recombinase from the Saccharomyces 
                     cerevisiae 2u plasmid"
                     /note="FLP-mediated recombination occurs in the 8-bp core 
                     sequence TCTAGAAA (Turan and Bode, 2011)."
     CDS             8954..8965
                     /codon_start=1
                     /product="Factor Xa recognition and cleavage site"
                     /label=Factor Xa site
                     /translation="IEGR"
ORIGIN
        1 cccccccccc taacgttact ggccgaagcc gcttggaata aggccggtgt gcgtttgtct
       61 atatgttatt ttccaccata ttgccgtctt ttggcaatgt gagggcccgg aaacctggcc
      121 ctgtcttctt gacgagcatt cctaggggtc tttcccctct cgccaaagga atgcaaggtc
      181 tgttgaatgt cgtgaaggaa gcagttcctc tggaagcttc ttgaagacaa acaacgtctg
      241 tagcgaccct ttgcaggcag cggaaccccc cacctggcga caggtgcctc tgcggccaaa
      301 agccacgtgt ataagataca cctgcaaagg cggcacaacc ccagtgccac gttgtgagtt
      361 ggatagttgt ggaaagagtc aaatggctct cctaagcgta ttcaacaagg ggctgaagga
      421 tgcccagaag gtaccccatt gtatgggatc tgatctgggg cctcggtgca catgctttac
      481 atgtgtttag tcgaggttaa aaaaacgtct aggccccccg aaccacgggg acgtggtttt
      541 cctttgaaaa acacgatgat aatatggcca caaccatggc tgagccccgc caggagttcg
      601 acgtgatgga agatcatgct cagggggact acaccctgca agaccaggag ggtgacatgg
      661 accccggcct gaaagagtct cccctgcaga ccccggccga tgatggatct gaggaaccag
      721 gctctgaaac ctctgatgct aagagcactc cgacggcgga agatgcgaca gcacccttag
      781 tggatgaggg agcccccggt gagcaggcgg ccgctcaggc ccccgcggag atcccagaag
      841 gaaccgcagc tgaagaagca ggcattggcg acacgtccaa cctggaagac caagctgccg
      901 gacacgtgac ccaagctcgc atggtcagta aaggcaaaga tgggactgga cccgatgaca
      961 aaaaaaccaa gggggcggat ggtaagcctg gaacgaagat tgccacaccc cggggagcag
     1021 cccctccagg ccagaaaggc caggccaacg ccacccggat tccagcaaaa accactccca
     1081 ccccgaagac ctcgccaggt gaatctggga aatccgggga ccgcagcggc tacagcagcc
     1141 ccggctcccc aggcactccg ggcagccgct cccgcacacc ctccctgccg accccgccca
     1201 cccgggagcc caagaaggtg gcggtggtcc gcactccccc caagtcgccg tctgcagcca
     1261 agagccgcct gcaggccgct cccgggccca tgccagacct gaagaacgtc aagtccaaaa
     1321 tcggctccac ggaaaacctg aagcaccagc caggaggtgg caaggtgcag ataattaata
     1381 agaagctgga tcttagcaac gtccagtcca agtgtggctc aaaggataat atcaaacacg
     1441 tgccaggagg cggcagtgtg caaatagtct acaaaccagt ggatctgagc aaggtgacct
     1501 ccaagtgtgg ctcattaggc aacatccatc ataagccagg aggtggccaa gtggaagtga
     1561 aatctgagaa gctggacttc aaggatagag tccagtcgaa gattgggtcc ctggacaaca
     1621 tcacacacgt ccctggcgga gggaataaaa agatcgaaac ccacaagctg accttccgcg
     1681 agaacgccaa agccaagacc gaccacgggg cggagatcgt gtccggggat cccgtcgttt
     1741 tacaacgtcg tgactgggaa aaccctggcg ttacccaact taatcgcctt gcagcacatc
     1801 cccctttcgc cagctggcgt aatagcgaag aggcccgcac cgatcgccct tcccaacagt
     1861 tgcgcagcct gaatggcgaa tggcgctttg cctggtttcc ggcaccagaa gcggtgccgg
     1921 aaagctggct ggagtgcgat cttcctgagg ccgatactgt cgtcgtcccc tcaaactggc
     1981 agatgcacgg ttacgatgcg cccatctaca ccaacgtgac ctatcccatt acggtcaatc
     2041 cgccgtttgt tcccacggag aatccgacgg gttgttactc gctcacattt aatgttgatg
     2101 aaagctggct acaggaaggc cagacgcgaa ttatttttga tggcgttaac tcggcgtttc
     2161 atctgtggtg caacgggcgc tgggtcggtt acggccagga cagtcgtttg ccgtctgaat
     2221 ttgacctgag cgcattttta cgcgccggag aaaaccgcct cgcggtgatg gtgctgcgct
     2281 ggagtgacgg cagttatctg gaagatcagg atatgtggcg gatgagcggc attttccgtg
     2341 acgtctcgtt gctgcataaa ccgactacac aaatcagcga tttccatgtt gccactcgct
     2401 ttaatgatga tttcagccgc gctgtactgg aggctgaagt tcagatgtgc ggcgagttgc
     2461 gtgactacct acgggtaaca gtttctttat ggcagggtga aacgcaggtc gccagcggca
     2521 ccgcgccttt cggcggtgaa attatcgatg agcgtggtgg ttatgccgat cgcgtcacac
     2581 tacgtctgaa cgtcgaaaac ccgaaactgt ggagcgccga aatcccgaat ctctatcgtg
     2641 cggtggttga actgcacacc gccgacggca cgctgattga agcagaagcc tgcgatgtcg
     2701 gtttccgcga ggtgcggatt gaaaatggtc tgctgctgct gaacggcaag ccgttgctga
     2761 ttcgaggcgt taaccgtcac gagcatcatc ctctgcatgg tcaggtcatg gatgagcaga
     2821 cgatggtgca ggatatcctg ctgatgaagc agaacaactt taacgccgtg cgctgttcgc
     2881 attatccgaa ccatccgctg tggtacacgc tgtgcgaccg ctacggcctg tatgtggtgg
     2941 atgaagccaa tattgaaacc cacggcatgg tgccaatgaa tcgtctgacc gatgatccgc
     3001 gctggctacc ggcgatgagc gaacgcgtaa cgcgaatggt gcagcgcgat cgtaatcacc
     3061 cgagtgtgat catctggtcg ctggggaatg aatcaggcca cggcgctaat cacgacgcgc
     3121 tgtatcgctg gatcaaatct gtcgatcctt cccgcccggt gcagtatgaa ggcggcggag
     3181 ccgacaccac ggccaccgat attatttgcc cgatgtacgc gcgcgtggat gaagaccagc
     3241 ccttcccggc tgtgccgaaa tggtccatca aaaaatggct ttcgctacct ggagagacgc
     3301 gcccgctgat cctttgcgaa tacgcccacg cgatgggtaa cagtcttggc ggtttcgcta
     3361 aatactggca ggcgtttcgt cagtatcccc gtttacaggg cggcttcgtc tgggactggg
     3421 tggatcagtc gctgattaaa tatgatgaaa acggcaaccc gtggtcggct tacggcggtg
     3481 attttggcga tacgccgaac gatcgccagt tctgtatgaa cggtctggtc tttgccgacc
     3541 gcacgccgca tccagcgctg acggaagcaa aacaccagca gcagtttttc cagttccgtt
     3601 tatccgggca aaccatcgaa gtgaccagcg aatacctgtt ccgtcatagc gataacgagc
     3661 tcctgcactg gatggtggcg ctggatggta agccgctggc aagcggtgaa gtgcctctgg
     3721 atgtcgctcc acaaggtaaa cagttgattg aactgcctga actaccgcag ccggagagcg
     3781 ccgggcaact ctggctcaca gtacgcgtag tgcaaccgaa cgcgaccgca tggtcagaag
     3841 ccgggcacat cagcgcctgg cagcagtggc gtctggcgga aaacctcagt gtgacgctcc
     3901 ccgccgcgtc ccacgccatc ccgcatctga ccaccagcga aatggatttt tgcatcgagc
     3961 tgggtaataa gcgttggcaa tttaaccgcc agtcaggctt tctttcacag atgtggattg
     4021 gcgataaaaa acaactgctg acgccgctgc gcgatcagtt cacccgtgca ccgctggata
     4081 acgacattgg cgtaagtgaa gcgacccgca ttgaccctaa cgcctgggtc gaacgctgga
     4141 aggcggcggg ccattaccag gccgaagcag cgttgttgca gtgcacggca gatacacttg
     4201 ctgatgcggt gctgattacg accgctcacg cgtggcagca tcaggggaaa accttattta
     4261 tcagccggaa aacctaccgg attgatggta gtggtcaaat ggcgattacc gttgatgttg
     4321 aagtggcgag cgatacaccg catccggcgc ggattggcct gaactgccag ctggcgcagg
     4381 tagcagagcg ggtaaactgg ctcggattag ggccgcaaga aaactatccc gaccgcctta
     4441 ctgccgcctg ttttgaccgc tgggatctgc cattgtcaga catgtatacc ccgtacgtct
     4501 tcccgagcga aaacggtctg cgctgcggga cgcgcgaatt gaattatggc ccacaccagt
     4561 ggcgcggcga cttccagttc aacatcagcc gctacagtca acagcaactg atggaaacca
     4621 gccatcgcca tctgctgcac gcggaagaag gcacatggct gaatatcgac ggtttccata
     4681 tggggattgg tggcgacgac tcctggagcc cgtcagtatc ggcggaattc cagctgagcg
     4741 ccggtcgcta ccattaccag ttggtctggt gtcaaaaata ataataaccg ggcagggggg
     4801 atccactagg gggatcttga agttcctatt ccgaagttcc tattctctag aaagtatagg
     4861 aacttcagag cgcttttgaa gctagcgaat tctaccgggt aggggaggcg cttttcccaa
     4921 ggcagtctgg agcatgcgct ttagcagccc cgctgggcac ttggcgctac acaagtggcc
     4981 tctggcctcg cacacattcc acatccaccg gtaggcgcca accggctccg ttctttggtg
     5041 gccccttcgc gccaccttct actcctcccc tagtcaggaa gttccccccc gccccgcagc
     5101 tcgcgtcgtg caggacgtga caaatggaag tagcacgtct cactagtctc gtgcagatgg
     5161 acagcaccgc tgagcaatgg aagcgggtag gcctttgggg cagcggccaa tagcagcttt
     5221 gctccttcgc tttctgggct cagaggctgg gaaggggtgg gtccgggggc gggctcaggg
     5281 gcgggctcag gggcggggcg ggcgcccgaa ggtcctccgg aggcccggca ttctgcacgc
     5341 ttcaaaagcg cacgtctgcc gcgctgttct cctcttcctc atctccgggc ctttcgacct
     5401 gcagccaata tgggatcggc cattgaacaa gatggattgc acgcaggttc tccggccgct
     5461 tgggtggaga ggctattcgg ctatgactgg gcacaacaga caatcggctg ctctgatgcc
     5521 gccgtgttcc ggctgtcagc gcaggggcgc ccggttcttt ttgtcaagac cgacctgtcc
     5581 ggtgccctga atgaactgca ggacgaggca gcgcggctat cgtggctggc cacgacgggc
     5641 gttccttgcg cagctgtgct cgacgttgtc actgaagcgg gaagggactg gctgctattg
     5701 ggcgaagtgc cggggcagga tctcctgtca tctcaccttg ctcctgccga gaaagtatcc
     5761 atcatggctg atgcaatgcg gcggctgcat acgcttgatc cggctacctg cccattcgac
     5821 caccaagcga aacatcgcat cgagcgagca cgtactcgga tggaagccgg tcttgtcgat
     5881 caggatgatc tggacgaaga gcatcagggg ctcgcgccag ccgaactgtt cgccaggctc
     5941 aaggcgcgca tgcccgacgg cgatgatctc gtcgtgaccc atggcgatgc ctgcttgccg
     6001 aatatcatgg tggaaaatgg ccgcttttct ggattcatcg actgtggccg gctgggtgtg
     6061 gcggaccgct atcaggacat agcgttggct acccgtgata ttgctgaaga gcttggcggc
     6121 gaatgggctg accgcttcct cgtgctttac ggtatcgccg ctcccgattc gcagcgcatc
     6181 gccttctatc gccttcttga cgagttcttc tgaggggatc cgctgtaagt ctgcagaaat
     6241 tgatgatcta ttaaacaata aagatgtcca ctaaaatgga agtttttcct gtcatacttt
     6301 gttaagaagg gtgagaacag agtacctaca ttttgaatgg aaggattgga gctacggggg
     6361 tgggggtggg gtgggattag ataaatgcct gctctttact gaaggctctt tactattgct
     6421 ttatgataat gtttcatagt tggatatcat aatttaaaca agcaaaacca aattaagggc
     6481 cagctcattc ctcccactca tgatctatag atctatagat ctctcgtggg atcattgttt
     6541 ttctcttgat tcccactttg tggttctaag tactgtggtt tccaaatgtg tcagtttcat
     6601 agcctgaaga acgagatcag cagcctctgt tccacataca cttcattctc agtattgttt
     6661 tgccaagttc taattccatc agaagcttcc atggggatcc gggggatctt gaagttccta
     6721 ttccgaagtt cctattctct agaaagtata ggaacttcag agcgcttttg aagctgggta
     6781 cattaattaa ggtaccggcg cgcctcaagg gagaaaatga agccctggga tccatttcct
     6841 atattcatgg caggaaagaa cattgacttg taaaaaaatg cagaagttca aaatgtggtc
     6901 ctttccatat cttcctcagg acccctttga gaataaataa ttaggaatga aacacaagcc
     6961 tggaggtttg gaaaatgctt tgcagtgatg gttcatggcc aatcttcagc tgacttgggc
     7021 tgtgtttgtt ctagatgtcg gctttgccgg tgggtctgtt tctgtttgct tgctctcagc
     7081 tccaccactt cccaaccctt gcctctggag aggtgccctg ggtccacttt cacaggacac
     7141 cctgactttg ggctccagtg tgccgtttaa ctggtagtgg gaggagagag aaggaggggt
     7201 tagagaccca gaccctgtgg tttatggtac ccctatgaca gctgtgctgt ggaaggcact
     7261 gggccagcag cgtgaaatgt agccattttc ccttcccagt cctgggaatt ctggaaagca
     7321 acagaacgaa agccacattt cccaggagat ctttttctga aaagtaaaat gaaaagaaaa
     7381 acaaacaaac aaacaaaaca aaacaaactg aaaacagcca aagggcagat ttgggaaaga
     7441 atagagccaa ggccaagtcc tgcccaacac ccaggtcctg gacgtggcgg gggacatgtg
     7501 cagttgtgct caggtcttga ctttgtgtgt ctccccctat cacttcccac ttcatgttct
     7561 gaggcaagat ctctcactga atctggagtt tgctggtttg gctacactgg tcaggtaccc
     7621 cttccagcat ccacctgtct cagctcccaa actggagtta caggcgtcct gatttcacat
     7681 ggtccctata cccacaacaa gaattttacc cacactaagt ctctccccca gtccaactta
     7741 acaggctttg tgagaattcc atgaagttaa gatgacaaca gtgctcatgg tagcagtggt
     7801 tggtaacact atgtatgcat caactgcgca ccaggcactg gccctgcatg cagatgttgc
     7861 ttgcacccta attactagag ataaccctgt ttgacagccc atctagattc atcttgatgg
     7921 accaggaaat gggagcacgg cagagttaac agtctgagtc cgtactgctg ggaaacagcc
     7981 tgactcttgg ttacaccaga gagagagaga gagagaggga gagagaggga gagagaagga
     8041 gagagagaga aagagagaga gggcagtttg gaggagtgga cccaggagac atacagagtc
     8101 acgttggaat ccccactcta tgttggaagt gccatcaagt caacaatgtt agggataatc
     8161 agataacctg ccttttgggg catttaaaaa ctgatcctaa gccgggcgtg gtggcgcatg
     8221 cctttaatcc tagcacttgg gaggcagagg caggcagatt tctgagttcg aggccagcct
     8281 ggtctacaga gtgagttcca ggacagccag ggctacacag agaaaccctg tctcgaaaaa
     8341 caaaacaaaa caaaacaaac aaacaaacaa acaaacaaaa aactgatcct aagtgtggca
     8401 tctccctgtt taagtgaggg gaaggaaaga cagcagaatt catagctcat tgctgtctcc
     8461 atctactttc ctttgaaact ctctagccat gtcttgagtg aaagccctag ctagaacgac
     8521 cactctgagg acgtggcatt acctgggaga ccaagaccaa attggtcatt tggtgggaag
     8581 ccttttcagt taagtttgga aggagaaaca ccagagcccg ggatcttgga ttattttgtt
     8641 gcaagcttgt ttggctgggg tcacagtaca atatgctact tcattgaaca ttatatttag
     8701 aactgtcaga attgtgcgac aggtaccata gtccaggcca aaaacaagga caatttttgt
     8761 tccacattta ttttgattta aataatcatt tccagctgta aaagaaagac aatcctgtga
     8821 taggtaccac cctgcagctg acatttattc tattaaacac tgctacagac aatctcctgg
     8881 tattcggaag tgtttgttac ttttctattg ctatgttact tatgctactt ctgttacttc
     8941 tatgaggcaa ctcatagaag gaaggtttta tttgtgctta cagttccaga gagctcagag
     9001 tccatcacag tggggaaggt tgaccattct catccaaacc accacacttg ggaagtttgg
     9061 cgagctgcta aagtgcttgc tcacagggcc tctaaaacct caaaatgcac cttcacttgt
     9121 tctggaatct tctgtgaatt gaggcccttg gacccaagtt agatgtatta actcctactg
     9181 gatcgattag ctcatagaac atctatgccc tggcacacac catctggtgg tctgtctcat
     9241 ggccagcagc agacctgggc tgccactcaa atacgaggct tgctcatgag cagtgaacac
     9301 ttggcttggt ggtgactgtc ggtagagccc ttttcagagt agagcattcc agggaactgc
     9361 cctctacaac tacagctttg caggctcagt ttaccccata accctgcctt gctcctgccc
     9421 ctccccctcc cttgcctctg ccccacctag cttcttccat ttcagggcac ctggcccagg
     9481 cacggtctat ccagatggtg gcagatggct ggtcctcaga ccaatgactg gcagactcat
     9541 tggcgtctag ccatggaggg aggcgacagt ttctaaataa gttgagaaga ggccactgct
     9601 ttctttacct tgggagcaca gacctcaagc ccaagcttgt aaaagccagg accccaaggt
     9661 cctgaatacc atggcaatcc tggatgctgg aggcaatgct tctgggcgct gaggaggagg
     9721 ggtgtctaca gctttctctt tcagtggctc tcttcttcct tagctgatgc ttcccgacac
     9781 ttccctcagt cttggtatct tagccctctc ctaggctaag actttttcat tcatcacaga
     9841 tgcctggctt ccccgccccc ccacccccca atcccttctt agtctttctt tcactttcaa
     9901 gttttcattg gctcacagtt gtgtgagaaa gaaagagtga gtgattcact gggttgcctg
     9961 gctgaggggt gagatcactg ctgcccctgc agagagtggg tgctgtgtgc tagcctggag
    10021 actgaagaaa gcaagcggag gaccgctctc cccagaagac catctggctg agacagccga
    10081 atgctaatct gtagctttca tttcctttat tcctcttggt ttgttctctt catctgcagc
    10141 tgtacattca gacccagccc ctgtgaaggc aagcgctcat ttggggagca tgtttatttg
    10201 cccccccacc ccccatgctt cttctaggtg tcgggaagcc attgttatca atggtgggtt
    10261 ctatgtggct ttaatgtcag tgctgcactt tcagatggaa atcaggcaat tatgtgccac
    10321 atagagaaac ctgacagatg cagaggtttt acacagctgg ccctgtctgt gggacaaagg
    10381 cacctggtgc tcccccgagg gatcattaca taagtagaat atgttttgag agcacagaaa
    10441 aactcaagaa taattaactg tggggtgagc attcatagac tctggggctg tgttaacttc
    10501 aaaatgtgat aatgatatgt caaccaactg gctgaatcat tctttaaagg tggcttgaga
    10561 gactctgtct cccaaagaga aactgctctg agtttctgca tggtgcagtc cgaaaatttt
    10621 cagaggattc tgaattcttt cccctcaggg gttcaacttg atgtgaggtg aggaggaaat
    10681 gacagcagtt ccatgtctgc attcagtggg gtctaatgat ggcactctct tagatcttag
    10741 tggcctatct aagccatcag catctaccca ggaacttggg ttcacatata tagcaggacc
    10801 attgtggtac ccagctgaag tcctttgagc attacacagg tatggttttt agccacactg
    10861 cgcagacagg aaactgaggt acagacctag gacttggcct tcagacccac cctaccccaa
    10921 ctctgatctt agctctcagc cattggctag agccgtctct gtgttggaag cagagactgt
    10981 actcctgaca cagcagctcc agtcagatat gtgctgtcaa gaacagaaca ggagagacct
    11041 aaagaaaagt tacagtgtga tttttcactg gagacgtcca gctattaaaa gagactgaaa
    11101 catgaagtcc cagctttaag tgttccagca tacatttata gtttaccaca ggctacggtg
    11161 tccccaggtc tagtcagggc tcctgttggc tgtggagcaa atacttagag gttttttgac
    11221 cctttgactc cagcagaccc tggagtctcc cccagatccc tgagctgtgg ttttagatta
    11281 tgcacagctg tggcagttta gaacagaaaa atatagggga ttctgtaact ctcagaaaaa
    11341 atgattctaa aaatacaata tttgtattta tcctttgaga atttcataca tgtataaaat
    11401 atgtcttggt catattcacc ccccactcta tcccaaaagt aatttttaaa ctcagcatat
    11461 gataaacaaa ttaagcaggt ttacgcaggg ctcttactcc ctttgcaaag ctacaaatgc
    11521 caattttgaa agactgtgaa gccctgtttt agagacattg tataaatcta ccaaaactgg
    11581 acacattagg aacaaaacag atttgcaagt ggtaaataaa cagtatgcag tcataatctc
    11641 cccgtcctca tgtgttttcc tctgtgctaa gtagagagac agtggaggcc attcagagcc
    11701 tcaccattgt cagtgtcatt agtgatggga agctggacac tgcacgtgta cctttcccat
    11761 ctcgactgaa tgtgcccatc tcaaggcatt attgtacgat gccagcatca cctgttttaa
    11821 aatattctta gtgtcttact aggcctcagg gatgatgccc ctatatacta taacttgttg
    11881 ggctctcatt tgggcaggta tgttggtaag actttatggg tgtggcttct tatgttacta
    11941 ggaaacacag tctcacagaa aactccctgt tcctctggct cttacagtct ttccacccca
    12001 gcttctgcag tgttccctga gctgtaggtg gggagtgttt tatagatgca tcctttgcga
    12061 tttggctcca gaattctgat ttatggggtt ttttagtggg ctccatctgt tgcaaagaga
    12121 aatgtccctg ataaggagta tagcaacact aacttacctg taagtataca tatgtctata
    12181 gattgttgtt ttgaatcatg ctggtttagt aaattagtgg ttgtagagtt tcctccaaga
    12241 accaagattt cgctagcact gagtagttag ctaggttacc actaccaggc atggcttccc
    12301 tcctgttgag tgggtcttaa atccaactta gagagttgtt ggttacaacc aaggtgtgtg
    12361 tgccactact gtatccttag ggctattatt gtggcattct agctggtttt tttgtgttcc
    12421 ttccaccttc ttctgattta cctcccagcc tagctccagg tggagaatga ctcattagag
    12481 cacccaacac cctcctctgg cctatggccc cacacacatg tacatcgacc acacatccac
    12541 atgtgtaaca tccccttcca cacacccaac acacaaagtc taaccatcta gaagtacaag
    12601 gttagagaac tcatggtgag agacccctag ccagtttcta gctacttttg tagtggggcc
    12661 aacatgaaat actcagaaac aaagggggag agcctccaga ggactctagc ccagccaaca
    12721 tggttataac cacacataaa ttctacctgg gaactcccag ctaagcctaa tcagcctaca
    12781 gagcgagaag agaattatgc actgtggttc tagccactga atttaaggta gcaaatgata
    12841 taatttagac aacttgaaga catttttctg acacatcagg atttagctcc tcattaatga
    12901 actctgtaga ctgcagtctt gcataataac ttcaagcagt ttatatgaat aaacttttgc
    12961 cactacatac tgtgatgggt caatagatcc ctggaactgg gatcactatg agaggaaaaa
    13021 tacattatga cttggaatta tttttttcct ctgttcaagc catccacttc cttgtatgtt
    13081 atgtgtttat tttattaggg ttactattag ggttattatg aaggttggtg acttaggtca
    13141 gcaggtaaag gccctgggtg tcaagtctga taacctgagt ttgatttcca gggccaacat
    13201 agtagaaggg gggaaccagt ttccaaaagt cctctgtgtc cacacacgag cgcgcgcacg
    13261 caaacacaca ctgaaactga aaatcaaact aaaacataaa accaggaaga aaaatatccc
    13321 caaccttcaa aaaaaaaaaa aaaaaaaaaa aaac
//
