LOCUS       sequence-353384-       15660 bp    DNA     circular SYN 14-APR-2025
DEFINITION  The SVA (SINE-VNTR-ALU) retroposon that causes human X-linked 
            Dystonia Parkinsonism (XDP), within a BAC (pJazz) backbone..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 15660)
  TITLE     SVA sequence that is causative for human X-lnked dystonia 
            Parkinsonism (XDP)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 15660)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Apr 14, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: 
            "Unpublished"
COMMENT     Sequence Label: pEF274 SVAfw
FEATURES             Location/Qualifiers
     source          1..15660
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     misc_feature    1..28
                     /gene="telR"
                     /label=telR
                     /note="telomeric sequence from coliphage N15"
     terminator      1115..1146
                     /label=tonB terminator
                     /note="bidirectional E. coli tonB-P14 transcription 
                     terminator"
     CDS             complement(1160..1819)
                     /codon_start=1
                     /gene="cat"
                     /product="chloramphenicol acetyltransferase"
                     /label=CmR
                     /note="confers resistance to chloramphenicol"
                     /translation="MEKKITGYTTVDISQWHRKEHFEAFQSVAQCTYNQTVQLDITAFL
                     KTVKKNKHKFYPAFIHILARLMNAHPEFRMAMKDGELVIWDSVHPCYTVFHEQTETFSS
                     LWSEYHDDFRQFLHIYSQDVACYGENLAYFPKGFIENMFFVSANPWVSFTSFDLNVANM
                     DNFFAPVFTMGKYYTQGDKVLMPLAIQVHHAVCDGFHVGRMLNELQQYCDEWQGGA"
     primer_bind     1734..1753
                     /label=CAT-R
                     /note="Chloramphenicol resistance gene, reverse primer"
     promoter        complement(1820..1922)
                     /label=cat promoter
                     /note="promoter of the E. coli cat gene encoding 
                     chloramphenicol acetyltransferase"
     terminator      complement(1926..1971)
                     /label=rrnB T1 terminator
                     /note="transcription terminator T1 from the E. coli rrnB 
                     gene"
     terminator      5420..5447
                     /label=T7Te terminator
                     /note="phage T7 early transcription terminator"
     CDS             5746..6354
                     /codon_start=1
                     /gene="cB"
                     /product="repressor protein of coliphage N15"
                     /label=CB
                     /translation="MIKGMKTRGERLKARRLELKLTLKQVAEAVGISLPGVQNLERGDV
                     MPSLEIGLSLAKCLRKPVQWILYGTESDPDRVPVIGTTETGPDRDWQPGEPANTERFLP
                     FVSQRNTVYALTVGNQIQRNYQPGDVILVDSSLTLVPGEDVLVCDNNGEITIQRLARYD
                     EQHYYLDSANSQRVIHDKSDLQFVHQVVGTIKSFMVEGR"
     CDS             6603..10577
                     /codon_start=1
                     /gene="repA"
                     /product="replication protein of coliphage N15"
                     /label=RepA
                     /translation="MTLQEFYAERFGSDPFSLLDAARDELTELAKMAGINWPACADKIQ
                     LNPRGGVERYTTYNNSSPEALQKSLKGRVEIYSRLEQSKDGISYPFVNFVEKAHDAGSW
                     SGFSFLFSEYRREQQRNGATVVAQPEEERARMERQAEARRLRAEQQRVNDLKNNQMEQE
                     RLLGWLAFHRAWEHSPAEDGSWPYAVKKGIRDVFGACDIRRVTSHDSAKWSRGPTTYMA
                     IPLSHLDGRKDGRIVGWQRIDLNGGKFQTSAITNGDFVGACFVIGDLQGAQKIATAEGF
                     ATGASIWLATRNDPKKRFDAVVIAVSANNMIHVVEQLVNMYPAAQITCALDNDRKSSAE
                     GKGNTGLRTGFDIMEKFSGVKCVYPTFEDDPELECSDFNDLHSLRGLKEVARQLTRNHL
                     SRATDLLSITLNKLRTLPRLNRRTFAKELLRAVDIGMLTCPVPNSPKELMRLFSSTLRD
                     MGIAEIYNGTVKDHITRRLNRKCRAAQTSRSFSERITNPNLRPSHITYKRFETSRMTDE
                     VMTYAAQLQGIVIVRAGMGSGKSTGLLRPLMLQSTRGVSVAHRVSLIGGLHEMMTEGKG
                     AKADILHYQDPGYQEMAPYANKLTICINSILKGCWQPLMRQHDFFGFDEATQGLRAILA
                     GRAMENPVGVFNTLIDALARTEEHAIMVDADANDLLVDLAELAMKRREELGLPAWLQIH
                     VIELPVDVRNRETNKPIRVFYTEKNRIMTEVIAAVQRGERIMLATDSSTFAEDVTMQLR
                     LQFPDKKFLCVNQKNKQEKEVDDFTNQPKVMVKKYDGLIYSPSISSGVSIEEKHFHRHF
                     GMFCGEVVPSDAIQMLRRDRTAQEYIIGFDKLRGKRETDPEKIKRAYAQALLETAGHSG
                     LLTDVVFDGDRISLGVANSSFMQLKIKAAALEASARNDYASNMICIMHDDGYQVAPMAT
                     DALANSIGKDLRKEARELVFEQLMERHLSVDTPDQAEHDELIKKRTLSLDEQAQLVRWD
                     IEKELQLDVDEVALKFYFDGGLKKVRLFETMQLDEITARRLDREEALIHFTYAYRVAGR
                     WQQFVTTAMTREQADAEFQAKFPAITDYRVKSTPAVEIGMRGFYTLKSATLQQYFRDCG
                     IDPKTLEGEADMDALKRARDNLLTPERRDLLNNVLRIGGFNTEKGKKKAPADLCIGILE
                     SMGLSSKTRRARDGDARPTMRSIDPDSVEFLMNIVEKRREAGLSIHARKVEKTTIEVDR
                     DLDLNIDIHGNPRSKTEHVPDAPQSVIIQALEAIPVAVPEAWAENALPATEMEAVRLWP
                     VASIARTFASLYMTEFMDLLSVREIRLLKAFLSQRQAVAI"
     rep_origin      10237..10326
                     /label=N15 ori
                     /note="bidirectional replication origin of coliphage N15"
     CDS             complement(13573..15468)
                     /codon_start=1
                     /gene="telN"
                     /product="protelomerase of coliphage N15"
                     /label=TelN
                     /note="generates the covalently closed hairpin telomeres"
                     /translation="MSKVKIGELINTLVNEVEAIDASDRPQGDKTKRIKAAAARYKNAL
                     FNDKRKFRGKGLQKRITANTFNAYMSRARKRFDDKLHHSFDKNINKLSEKYPLYSEELS
                     SWLSMPTANIRQHMSSLQSKLKEIMPLAEELSNVRIGSKGSDAKIARLIKKYPDWSFAL
                     SDLNSDDWKERRDYLYKLFQQGSALLEELHQLKVNHEVLYHLQLSPAERTSIQQRWADV
                     LREKKRNVVVIDYPTYMQSIYDILNNPATLFSLNTRSGMAPLAFALAAVSGRRMIEIMF
                     QGEFAVSGKYTVNFSGQAKKRSEDKSVTRTIYTLCEAKLFVELLTELRSCSAASDFDEV
                     VKGYGKDDTRSENGRINAILAKAFNPWVKSFFGDDRRVYKDSRAIYARIAYEMFFRVDP
                     RWKNVDEDVFFMEILGHDDENTQLHYKQFKLANFSRTWRPEVGDENTRLVALQKLDDEM
                     PGFARGDAGVRLHETVKQLVEQDPSAKITNSTLRAFKFSPTMISRYLEFAADALGQFVG
                     ENGQWQLKIETPAIVLPDEESVETIDEPDDESQDDELDEDEIELDEGGGDEPTEEEGPE
                     EHQPTALKPVFKPAKNNGDGTYKIEFEYDGKHYAWSGPADSPMAAMRSAWETYYS"
     misc_feature    15633..15660
                     /gene="telL"
                     /label=telL
                     /note="telomeric sequence from coliphage N15"
ORIGIN
        1 gcgtataatg ggcaattgtg tgctgatatg ttccgtaatt gagatatgat atagtgcata
       61 tgttccgaat tattgataca ttaatgttgc attcctatgt tgtgttctgt tatggtgttc
      121 ttagatagtg ggggatgtca catggattga tgttctttga ttgtgtttca atatagagac
      181 ggaagagata gagatgcctc aaagtgtata aacagcgtga aaatcagcat gttcgcttaa
      241 cttttgatag caattggtat gatttattat catttaaaat cattaagtta ggttttaaat
      301 ataccaacgt aagtaatacc gttgcgctta gatgaagcta aatagcttct gtagcgcatc
      361 aaaaaattga tttgaacctt aactttgcgt tttctaagtc actttgcttt ttttatgttg
      421 ctttgcttta aaaacgtaaa gtatgatgaa aaacacaaag ataagggcat gtttgagagg
      481 aaacaggatg tcgttaatta atttgctgaa agactgtatc aatcgcggtc aggaaatgac
      541 gcgcgctatt gccatcgcac agttcggcga tgacagcccg gaagcgcgtc gtattactcg
      601 ccgctggggt ataacagaag ttgcagacct gatcggcgta acaccgcagg ctatcagaga
      661 cgcggaaaaa gctggtcgtc taccggctcc tgattttgag atgaggggcc gagtagaacg
      721 tcgcgctggc tacacaattg accaaattag ccatatgcgg agtgtgtttg gtaacccaaa
      781 ccaaagacct gacgataaaa acccggttgt actttccgtt atgtcacaca agggaggggt
      841 ttataaaacc tcatctgcag tacaccaggc gcaatggtta gccttgcaag ggcaccgcgt
      901 cctactcgtt gaagggaacg acccgcaagg gactgcatct atgtaccacg gttacgttcc
      961 tgatttgcac attcacgcag acgatacact gcttccattt tacctgggta aacgcgacaa
     1021 cgctgaatat gcgataaaac caacatgctg gccgggtctc gacataatcc ccagctgcct
     1081 ggcccttcac cgcattgaaa cagatctagc agaaagtcaa aagcctccga ccggaggctt
     1141 ttgacttctg tcacctaggt tacgccccgc cctgccactc atcgcagtac tgttgtaatt
     1201 cattaagcat tctgccgaca tggaagccat cacaaacggc atgatgaacc tgaatcgcca
     1261 gcggcatcag caccttgtcg ccttgcgtat aatatttgcc catggtgaaa acgggggcga
     1321 agaagttgtc catattggcc acgtttaaat caaaactggt gaaactcacc cagggattgg
     1381 ctgagacgaa aaacatattc tcaataaacc ctttagggaa ataggccagg ttttcaccgt
     1441 aacacgccac atcttgcgaa tatatgtgta gaaactgccg gaaatcgtcg tggtattcac
     1501 tccagagcga tgaaaacgtt tcagtttgct catggaaaac ggtgtaacaa gggtgaacac
     1561 tatcccatat caccagctca ccgtctttca ttgccatacg aaattccgga tgagcattca
     1621 tcaggcgggc aagaatgtga ataaaggccg gataaaactt gtgcttattt ttctttacgg
     1681 tctttaaaaa ggccgtaata tccagctgaa cggtctggtt ataggtacat tgagcaactg
     1741 actgaaatgc ctcaaaatgt tctttacgat gccattggga tatatcaacg gtggtatatc
     1801 cagtgatttt tttctccatt ttagcttcct tagctcctga aaatctcgat aactcaaaaa
     1861 atacgcccgg tagtgatctt atttcattat ggtgaaagtt ggaacctctt acgtgccgat
     1921 cagattaaaa cgaaaggccc agtctttcga ctgagccttt cgttttattt gaccatgttg
     1981 gtatgattta aatggtcagt taatcagttc tatgtaccag caaggtccag ttgtaagcgg
     2041 ccgcttgact tcaagtctaa tggcccaaac gaattcgccc tttgctgcag agaaactgga
     2101 tcacatacat tgctggtggg aatgtaaaat ggtacagaca ctccaaaagt gtggcacaat
     2161 ctttttgtag ttcataagct tatgatgacg taagtgtgac gacattgggt tttcacgttc
     2221 atgtgtgaga tgtgcctccc tcaagcctta ttacaatgcc agtacatttt ttttccacat
     2281 ctgatgtgga aaaaaaaaaa atgaaatagc tctccctctc cctctccctc tccctctccc
     2341 tctccctctc cctctccctc tccctctccc tctccctctc cctctccctc tccctctccc
     2401 tctccctctc cctctccctc tccctctccc tctccctctc cctctccctc tccctctccc
     2461 tctccctctc cctctccctc tccctctccc tctccctctc cctctccctc tccctctccc
     2521 tctccctctc cctctccctc tccctctccc tctccctctc cctctccctc tccctctccc
     2581 tctccctctc cctctccctc tccctctccc tctccctctc cctctcctcc ctctccctct
     2641 ccccacggtc tccctctcat gcggagccaa agctggactg tactgctgcc atctcggctc
     2701 actgcatcct ccctgcctga ttctcctgcc tcagtctgcc gagtgcctgc gattgcaggc
     2761 acgcgccgcc acgcctgact ggttttggtg gagacagggt ttcgctgtgt tggccgggcc
     2821 ggtctccagc ccctaaccgc gagtgatccg ccaacctcgg cctcccgagg tgccgggatt
     2881 gcagacggag tctcgttcac tcagtgctca atggtgccca ggctggagtg cagtggcgtg
     2941 atctcggctc actacaaccc acacctccca gccgcctgcc ttggcctccc aaagtgccga
     3001 gattgcagcc tctgcccggc cgccaccccg tctgggaagg gaggagtgtc tctgcctggc
     3061 cgcccatcgt ctgggatgtg aggagcccct ctgcctggct gcccagtctg gaaagtgagg
     3121 agcgtctccg cccggccgcc atcccatcta ggaagtgagg agcacctctt cccggccgcc
     3181 atcacatcta ggaagtgagg agcgtctctg cccggccgcc catcgtctga gatgtgggga
     3241 gcgcctctgc cccgccgccc catctgggat gtgaggagcg cctctgcccg gccgagaccc
     3301 cgtctgggag gtgaggagcg tctctgcccg gccgccccgt ctgagaagtg aggagaccct
     3361 ctgcctggca accaccccgt ctgagaagtg aggagcccct ccgcccggca gctgccccgt
     3421 ctgagaagtg aggagcctct ccgcccggca gccaccccat ctgggaagtg aggagcatct
     3481 ccgcccagca gccaccccgt ccgggaggga ggtggggggg ggtcagcccc ccacccggcc
     3541 agccgcccca tccgggaggg aggtgggggg tcagcccccc cgcccggcca gccgtgccat
     3601 ccgggaggga ggtggggggg tcagcccccc gcccggccag ccgccccgtc cgggaggtga
     3661 ggggcgcctc tgcccggccg cccctactgg gaagtgagga gcccctcagc ccggccagcc
     3721 accccgtccg ggagggagat gggggggtca gcccccccac ccggccagcc gccccgtccg
     3781 ggagggaggt gggggggtca gccccccgcc tggccagccg ccccgtccgg gagggaggtg
     3841 ggggggtcag ccccccgccc ggccagccgc cccgtctggg aggtgagggg cgcctctgcc
     3901 cggccgcccc tactgggaag tgaggagccc ctctgccagg ccagccgccc cgtccgggag
     3961 ggaggtgggg gggtcagccc cccgcccggc cagccgccct gtccgggagg gaggtggggg
     4021 ggtcagccct ccgcccggcc agccgccccg tctgggaggt gaggggcgcc tctgcccggc
     4081 cgcccctact gggaagtgag gagcccctct gcccggccag ccgccccgtc cgggagggag
     4141 gtgggggggt cggccccccg cccgaccagc cgccccatcc gggagggagg tgggggggtc
     4201 agccccccgc ccggccagcc gccctgtccg ggagggaggt gggggtgtca gccccacgcc
     4261 cggccagccg cctcgtccgg gagggaggtg ggggggtcag ccccccgccc ggccagccgc
     4321 cccgtccggg agggaggtgg ggggggtcag cccccctgcc cggccagtgg ccccgtccgg
     4381 gaggtgaggg gcgcctctgc ccggctgccc ctactgggaa gtgaggagcc cctctgccca
     4441 gccagccgcc ccgtccggga gggaggtggg gggggtcagc cccccccgcc cggccagccg
     4501 ccctgtccgg gaggtgaggg gcgcctctgc ccagccacca cccggtctgg gaggtgtgcc
     4561 caacagctca ttgagaacgg gccaggatga caatggcggc cttgtggaat agaaaggcgg
     4621 gaaaggcggg gaaaagattg agaaatcgga tggttgccgt gtctgtgtag aaagaagtag
     4681 acatgggaga cttttcattt tgttctgcac taagaaaaat tcctctgtct tgggatcctg
     4741 ttgatctgtg accttacccc caaccctgtg ctctctgaaa catgtgctgt gtccactcag
     4801 ggttaaatgg attaagggcg gtgcaagatg tgctttgtta aacagatgct tgaaggcagc
     4861 atgctcgtta agagtcatca ccaatcccta atctcaagta atcagggaca caaacactgc
     4921 ggaaggccgc agggtcctct gcctaggaaa accagagacc tttgttcact tgtttatctg
     4981 ctgaccttcc ctccactatt gtcccatgac cctgccaaat ccccctctgt gagaaacacc
     5041 caagaattat maawaaaaaa awaaawwaaa aaaaaaawaa aaaaaaaaaa aaaaaaaaaa
     5101 aaaaaaatga aatagtgccg tgtcttgtaa aactaaacat ataccattct attcttgggc
     5161 atttatccca aagaaatgaa aaattaaact catccaaaac cctgtctatg attgctcaca
     5221 gcagctttac tcacaatggc aaaatagtga aaatctgaat gtccttcaat gagtaaatgt
     5281 ttgaacaaac gctggtacaa ccacacaatg gaacactcaa caatttgggc cattgggccc
     5341 tagacaagtt gtcgcggccg cactagtgac tccagcgtaa ctggactggc cacagttagg
     5401 ccgcaaatgt aatcacactg gctcaccttc gggtgggcct ttctgcgtct agaggatccc
     5461 cttgttatgc ccttccttac ccatgcgctg agaggtgaaa tcactcttta atttgtacgc
     5521 ggtacggacc tctatatcgc tttgtcgtag aggtggaatc tccccagctt gcagccattg
     5581 atagactgcg ccgggtgtca cgcccacgcc aaccgctgct ttttccacat cgccgaaatg
     5641 gcgcacaagt tcttcgggtt tcatggggat tattataatc aataagtgaa aattaaagct
     5701 aggtataatt tataaaaatt atagccagct ataaagagat catttatgat taagggtatg
     5761 aaaacacgag gcgaacgact gaaagcacgc cgtttagagc tgaaactgac gctgaagcaa
     5821 gtggcagaag ctgtaggaat ctctcttccg ggcgtccaaa acttagaacg tggcgacgtg
     5881 atgccgtcgc tggagatcgg gctatcgctg gcaaaatgcc tgcgtaagcc cgtgcaatgg
     5941 atactgtatg gcactgaatc tgatccagac cgcgttcctg ttattggtac gacagagacc
     6001 ggaccggata gagactggca gcctggagaa cctgccaaca cagagcgatt cctgccgttc
     6061 gtgagtcaac ggaacaccgt ttacgcactg acggtcggga accagattca gcgaaactac
     6121 cagccgggag acgttatcct ggtcgattct tcacttacgc ttgtaccggg tgaggatgta
     6181 ctggtttgtg ataataacgg cgagatcaca attcaacgat tagcccgtta tgacgagcag
     6241 cattactacc ttgatagtgc taactctcaa cgggttatcc atgataaaag tgatcttcaa
     6301 tttgtgcacc aagtagtcgg tacgatcaaa tcgttcatgg ttgagggtag atgatacaat
     6361 aacagggttt attgctgact ataattctgg tttaatccga tctatacttt gtcggggttg
     6421 aaccagaccg tagcagccga aaaaagacga aaaaaaaacc gagtcggcaa actcgggcct
     6481 ttttcaggaa gtagccacga taacgcagat acgtccttca gaaagatagt gcgtttattg
     6541 tggctgctcc tgcggatttt ttcaacccga aaaaatgcta attcgcatgg aaaggctaaa
     6601 aaatgacctt acaagaattc tacgcggagc gctttggcag cgatccgttt tcactgcttg
     6661 acgcggcacg tgatgagctg actgagctgg cgaagatggc cggtatcaac tggcctgcgt
     6721 gtgctgataa gattcagctc aatccgcgcg gtggtgtaga gcgctatacc acctacaata
     6781 attcctcccc ggaagctctg cagaagagcc ttaaaggccg tgtggaaatc tattcacgcc
     6841 ttgagcagag caaggatggc atcagttatc ctttcgttaa cttcgttgaa aaagcgcatg
     6901 acgctggctc ctggagtggc ttttcattcc tgttttcgga gtatcgccgt gaacagcaac
     6961 ggaatggtgc gaccgtggtc gctcagccgg aagaagaacg tgcacgcatg gagcgccagg
     7021 ctgaagcacg ccgcctccga gctgaacaac aacgcgttaa tgatttaaaa aacaatcaga
     7081 tggagcagga acgcctgctt ggatggttgg ctttccatcg cgcctgggaa cattcgccag
     7141 ctgaagatgg ctcctggcct tatgcggtaa aaaagggaat tcgtgacgta tttggcgctt
     7201 gtgatatacg tcgcgtgacc agtcacgaca gtgcgaaatg gagccgtgga ccaacaactt
     7261 acatggcgat acctctgtcc cacctggacg gaagaaaaga cgggcggatt gttggctggc
     7321 aacgtatcga tctgaatggt ggcaagttcc agaccagcgc catcactaac ggtgatttcg
     7381 tcggtgcatg ctttgttatt ggcgacctgc agggggcgca aaaaattgcg actgcagagg
     7441 gtttcgccac cggggcatcc atctggctgg cgaccagaaa cgacccgaaa aaacgctttg
     7501 acgcggtagt cattgcggtt tccgctaaca acatgattca cgttgtcgag cagctggtga
     7561 acatgtaccc ggctgcgcaa atcacttgcg ctctcgataa cgaccgcaaa tcctcagctg
     7621 aaggaaaagg caacacaggc ctccgcaccg gattcgacat catggagaag ttttccggcg
     7681 tcaaatgtgt ttacccaact tttgaggatg accctgagct ggaatgcagc gattttaacg
     7741 acctgcacag cctgagaggg ctgaaggaag tcgctcgcca gttaacgaga aatcatctga
     7801 gccgtgcaac cgatctgttg tcgatcacgc tgaataagct gcgtactctc ccgcgtctga
     7861 acagacgcac ttttgccaaa gaactgcttc gcgccgttga tattggcatg ctgacatgcc
     7921 cggtaccaaa cagcccgaaa gaacttatgc gccttttcag cagcacgctg cgggatatgg
     7981 gtatcgcaga aatttataac ggtaccgtta aagatcacat tacgcgccgg ttgaatcgca
     8041 aatgccgtgc cgcgcaaaca tcacgttcgt tcagtgaacg catcaccaac ccgaaccttc
     8101 gcccgtcaca catcacttac aaacggtttg aaacctccag gatgaccgat gaggtgatga
     8161 catacgccgc acagctgcag ggcatcgtta ttgtccgcgc cgggatgggg tcgggtaaat
     8221 cgacaggcct cctgcgtcca ctgatgctgc agtccacgcg tggcgtttcc gtcgcgcacc
     8281 gcgtatccct gataggcggc ctgcatgaaa tgatgaccga agggaaaggc gcgaaagccg
     8341 acattctgca ttatcaggat cccggctatc aggaaatggc gccatatgcc aacaagctga
     8401 ctatttgcat caactccata cttaaaggct gctggcaacc gctgatgcgc cagcatgact
     8461 tcttcggctt cgatgaagca acacagggcc tgcgtgccat tctggccggg cgtgcgatgg
     8521 aaaacccggt aggcgtattc aacacgctta tcgacgcgct ggcgcgtact gaagagcatg
     8581 ccattatggt ggatgccgat gccaacgatc tgcttgttga cctggctgaa ctggcgatga
     8641 agcgacgcga ggagctgggc ctacctgcct ggctgcaaat tcacgtgatt gaactcccgg
     8701 tcgacgttcg caaccgcgaa accaacaagc ctatccgcgt attttatacc gagaaaaatc
     8761 ggatcatgac cgaggttatc gctgcagtgc aacgcggcga acgaatcatg ctggccaccg
     8821 acagttcgac gttcgccgaa gacgttacca tgcagctgag actacagttc cctgacaaaa
     8881 agtttctctg cgttaaccag aaaaacaaac aggagaagga agtcgacgat ttcaccaacc
     8941 agcctaaagt gatggtgaaa aaatatgacg gcctcatcta cagcccgtcg atatcttcag
     9001 gtgtatcgat tgaggagaaa cacttccacc gccatttcgg catgttctgc ggcgaagtgg
     9061 tccccagcga cgccatccag atgctgcgcc gcgaccgtac agctcaggaa tacattatcg
     9121 gtttcgacaa gcttcgcggt aaacgtgaaa ccgatccgga aaaaatcaaa cgcgcctacg
     9181 cgcaggcctt gctcgaaacg gctggccact ccgggctgct gacagacgtt gtctttgacg
     9241 gtgaccgaat ttcactcggc gtggctaact cttcattcat gcagctcaaa attaaagccg
     9301 ccgcgctcga ggcatcggcc agaaatgatt atgccagcaa catgatttgc atcatgcatg
     9361 atgatggcta tcaggtcgcg cctatggcca ccgacgcgct tgcaaacagc atcggtaagg
     9421 atttacgtaa agaagcccgt gaactggtct ttgagcagct tatggagcgc cacctgagtg
     9481 tcgatactcc tgaccaggcc gaacacgatg agttgataaa aaaacgcacc ctgtccctgg
     9541 atgagcaggc ccagctggtc cgctgggaca tcgaaaagga gctgcagctg gatgtcgacg
     9601 aggtggcgtt aaaattctat ttcgacggcg gcctgaaaaa agtgcgcctg tttgaaacca
     9661 tgcagctgga tgagataacc gcccgtcgcc ttgaccgtga agaagcgttg attcacttta
     9721 cctacgctta tcgcgttgcc ggaagatggc agcagttcgt cactacggcc atgacgcggg
     9781 aacaggccga cgcagagttc caggctaaat tcccggccat aaccgattac cgagtgaaat
     9841 cgacccctgc tgttgagata ggcatgcgtg gtttctacac cctcaaatcg gcgacgctgc
     9901 agcagtactt ccgcgactgc ggtatcgatc caaaaaccct ggaaggtgaa gcagacatgg
     9961 acgccctcaa acgcgccaga gataacctgc tcacgccgga acggcgcgat ctgctaaaca
    10021 acgttttacg catcggcggc ttcaacacag agaaaggcaa gaagaaagcg cctgcagacc
    10081 tctgcatagg catcctggag tctatggggc tatccagtaa gaccagacgc gccagagacg
    10141 gcgatgcacg ccccacgatg cgttccattg acccggactc ggtcgagttc ctcatgaata
    10201 tcgtggagaa gcgccgcgag gccggtttat caattcacgc acgtaaggtg gaaaaaacca
    10261 ccatcgaagt ggatcgcgat ttggatctaa atatagatat acatggtaac cctcgatcca
    10321 aaacagagca cgttccggac gccccacaat cagtaattat ccaggcactg gaggctatcc
    10381 cggtggcggt accggaggcg tgggcggaga acgcgttgcc agcaaccgaa atggaggcgg
    10441 tacgcctgtg gccagtggcc agcatcgcga gaacgttcgc ctcgctgtac atgaccgaat
    10501 ttatggacct gctatcagta cgcgaaataa ggctgctgaa agcgtttcta agccagcggc
    10561 aagccgtggc gatataaccg gaggggtaat gggaaaacaa cgggaatgcc ttgtcatcgt
    10621 ggagggctac gacccttatg tggtcaaggt cagccacgac gcgacaagct atagcgatta
    10681 taaaactggc cgggaacttc cattcacgat cattcggatg aacgggttct cagatagtga
    10741 gggagtttat tgctgcattg ccagcgataa gagcatggaa gaccacacag acgaagccag
    10801 ggcgcttcta aaagcctata aggtgaagcc actatgacgt cgacaccaga gttcctgaag
    10861 caactggatt acgaacagct gaagtactgt cgcgagctgt gcgataaccg catccgggct
    10921 attgaggccg aagagaaaaa gatggcctgg gcagttactg atggtggcat taactacggc
    10981 tggttccgta cagaagacta catgaaggcg gtagaatgcc tggttgctac agctgcagaa
    11041 cggtgggaag aatcggataa ggctgaccca tctggacgtg gttggcttga cctttcaatc
    11101 cgtggaagcc gcctgccggt gtccgagtat gaagctttat ttgctgatgg ccagtggggg
    11161 tgaatagtgg cgcatgatct acaaaaaatg atggatggtg agctggtccg cttacaactt
    11221 gagattaaga aagaacagga gaggcgttta gccgaaaaga tgattcctgt ttttggtgtg
    11281 tggcaatcac ctattaatca atatgaattt gctgatccag agcaggcaat ttcttgtgcc
    11341 gcagggctat tggataaagt tcttcgtgag gtcaaggacg atctttccaa agaaggtgga
    11401 ttacagggat ggaacggcaa tttgctacgc atctacgtac agcatgtgaa cgagagcgat
    11461 tttgcagttc tacagcctta tttaaaggac aaataatcat gatttatcgc agaggatggg
    11521 tgcctgtttt gtggaggaat gagctggaaa agcggctcaa agaagaaggg ttcgaaaact
    11581 ggaagcagat aagtaacttt ctttgtggtg aagaggattg ctactcggaa gcagcaaaaa
    11641 cgccaggaca atacgcttac caggtcgtcg acaataccga atggatggaa cgtcgtgatg
    11701 cgacgttctg gcagcgtctg aaccgtttgt ggttcgttcc gctgtacctg ctgactattc
    11761 cgttccagtg gctcattcgt ggccgtatgg ggtttgagac aacatctaag gtggctgcgg
    11821 tcatcaataa gattaccgga ctccaataac tgatcaggtt ctgatcagtc agtaaagcaa
    11881 actataaaaa cacctgtgca cgtgactggt cacggggtaa aatatccacc taaattattg
    11941 acgtgcgttc tgctttggcg gtagagttac cccgctgcag caaaatctgc agccgggcct
    12001 ctcaaccccg aatgacaaga agcgcacaac acgcgccagc gtgttttttt gtgtgttaaa
    12061 tctgcgcata cctgaattat ggtggctcag atggggccaa cttcggttgg gccggtttct
    12121 tcttgtaccg gtgttgagaa ccctgtctgg gctaccaccc ctatagagat tctcaactct
    12181 ggtggtagca ccctatacaa gataggaatg cataccatgt tcaaattcaa atttgcagct
    12241 gtcgtccgca cggacaaaaa atcccatatc caccgccttt ccaccactgc atcatccgag
    12301 cgagaagctc gtcgccagtt cgccagccgt tttgtcctcg ttctgtcagc ccgtatcccg
    12361 gtcagcgagg tgatcgcatg aaccagattc agttaaacgc ccagggcctg ctggagacga
    12421 ttgaggaacg cctgctgcag gttgaagcgc ttgtgggctc tgctcaccgc actatctcca
    12481 gttatgaggc cacgctgtat ttgcaggaag ctgcggaact tctgcaggtc gcgcgcgaac
    12541 tcacgcagga agctcgcggc tgctccctgt ccctttctga gcagctgaaa tccggggagg
    12601 cgcaatgaag gctctctccg tcttttcatt tcaggaaagc caccctatac gggtggttct
    12661 tgtcggtggt gacccgtggt ttgtggcgct ggatatctgt gctgcattga atatagccaa
    12721 cccttctgat gcattgcgta agctggatca tgatgaaaaa ttgaccctcg gtttaaccga
    12781 ggcacaaaaa cttgatcgga tggccaggga agtaaatgtg gtatcggaat ctggtctcta
    12841 caccataatc ctccgctgcc gcgacgcggt gaaacagggg acgacagcct ggcggttccg
    12901 caagtgggtg acgaacgagg ttctgccagc tatccggaaa aacggcgagt atgcttttgt
    12961 cgagcctgag cctaagaacg ccggtgaacc actggactgg cggcagaaag aagaacttcg
    13021 gggcctgata aacgacatag cacaaagttt tcagtaccgt aacgcatggg ttagcggcgt
    13081 ctggatggct ctccgccgcg cctgcaggaa cccatcaccg aacccaataa ccgtggatga
    13141 tctcccggca atcatcgccg agctgcgccg gatattaacg gctgcagaaa cggctctggg
    13201 caacatgcgt gtctacgaac gggagctgct gcgcgatgta gttcgtggcg gtcgccggag
    13261 tatgtcttgt ggagagctgc cgatcaccga tattgatacg gaactggaga aggtgctgcc
    13321 agcacatttt gagctggcca ttgaaaagct ggaaacgcta tccacgaaac taacatcgcc
    13381 agcgattgca gaaaaatagg gttggccagc ccgaatttaa gccccgcttt acgcggggaa
    13441 gtccctgcag tcgggacggc gatgtccgta gttgcagctg cagtttccgc ctaatccttc
    13501 cgtcccttgc aggggatggg tagggacagg cctcaataaa aaagccaccg attaacaccg
    13561 gtggcttttc ttttagctgt agtacgtttc ccatgcggat cgcattgcgg ccatagggct
    13621 atcggcgggg ccggaccagg cataatgctt tccatcgtat tcaaactcta tcttgtacgt
    13681 tccgtccccg ttattttttg caggcttgaa gacgggtttt agagcagttg gctgatgttc
    13741 ttctggccct tcctcttcgg ttggttcatc gccgccaccc tcgtcgagct caatttcatc
    13801 ttcatccagc tcgtcgtctt gggactcatc atccggttcg tcgatggtct caacggattc
    13861 ttcatcaggc aggacgattg caggtgtctc tatcttcagc tgccactgcc cgttctcgcc
    13921 aacgaactgc cccaatgcat cagcggcaaa ctccaggtac cggctaatca tcgtcgggct
    13981 aaatttaaag gcccggagag tgctgttggt tatttttgct gatgggtcct gctccaccag
    14041 ctgcttaacg gtttcatgga gacggacgcc agcgtcacct ctggcaaagc ctggcatttc
    14101 atcgtccagt ttctgcagag ccaccagcct ggtgttttca tccccaactt caggtcgcca
    14161 ggttctggag aagttggcca gcttgaactg cttatagtgc agctgggtgt tctcatcgtc
    14221 gtgtccgaga atctccatga agaacacatc ctcgtcgacg tttttccacc gtggatcgac
    14281 gcggaagaac atctcataag cgatgcgagc gtaaatagcg cggctatctt tataaacacg
    14341 acggtcatcg ccgaaaaatg atttaaccca agggttaaat gcttttgcta aaatagcatt
    14401 tatcctgccg ttctcagacc ttgtatcatc ctttccatat cctttaacaa cctcatcgaa
    14461 atcagatgca gcagagcaag aacgcaattc tgttaataat tcaacgaata attttgcttc
    14521 gcataaagta taaatcgttc tggttacgct tttatcttca gagcgttttt tagcttgccc
    14581 tgagaaatta accgtatact ttcctgaaac ggcaaattca ccctgaaaca ttatctcaat
    14641 cattcttcgc cctgataccg cagccagagc aaaggccaaa ggtgccattc cagaacgagt
    14701 gtttaaacta aataaagtcg caggattatt caaaatatca tagatagact gcatgtatgt
    14761 tgggtagtca ataaccacaa cattacgctt cttctcgcgc agaacatcgg cccatcgttg
    14821 ctgtatagat gtacgctccg cagggcttag ctgcagatgg tacagaacct catggttgac
    14881 cttgagctgg tgtagttctt ctaacaacgc agagccttgt tggaataact tataaagata
    14941 gtcacggcgc tccttccaat catcactgtt taaatcacta agagcaaaac tccaatctgg
    15001 atattttttt attagtcttg ctatttttgc atcactgcct ttagagccta ttcttacatt
    15061 tgataactct tcggcaagcg gcattatttc tttcaattta gattgtaacg atgacatgtg
    15121 ctggcgaata ttagccgtag gcatagaaag ccatgaagat aattcttcgc tgtaaagagg
    15181 atacttttcc gataatttat taatattttt atcaaagcta tgatgtaatt tatcatcaaa
    15241 ccgctttctt gccctgctca tataggcgtt aaaagtattc gcggttattc ttttctgcaa
    15301 tcctttccca cggaactttc ttttatcatt aaataacgcg ttcttatacc gtgcggctgc
    15361 ggctttaatt ctcttcgttt tgtcgccttg tgggcggtct gaggcatcaa ttgcctctac
    15421 ctcattcaca agcgtgttga tcaactcacc gatttttacc ttgctcatcc cggttccccc
    15481 gtttctaagt ctctggatat cgtaacacaa tcaaagaaca agtggcgatt aattatgctg
    15541 ctttcgtcac actataagag aacataatag cagaataaca aaggaacaca acaccggaat
    15601 agatacatat tgttctgcgc ttatgttctc cttatcagca cacaatagtc cattatacgc
//
