LOCUS       sequence-446947-         720 bp    DNA     linear   UNA 14-APR-2025
DEFINITION  Expresses human BCL2alpha.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Goodis CC, Eberly C, Chan AM, Kim M, Lowe BD, Civin CI, Fletcher S
  TITLE     The polypharmacy combination of the BCL-2 inhibitor venetoclax (VEN)
            and the FLT3 inhibitor gilteritinib (GIL) is more active in acute 
            myeloid leukemia cells than novel polypharmacologic BCL-2/FLT3 
            VEN-GIL hybrid single-molecule inhibitors.
  JOURNAL   Eur J Med Chem. 2024 Dec 22;285:117190. doi: 
            10.1016/j.ejmech.2024.117190.
  PUBMED    39813774
REFERENCE   2  (bases 1 to 720)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Apr 14, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Eur J Med 
            Chem."; date: "2024-12-22"; volume: "285:117190. doi"; pages: " 
            10.1016/j.ejmech.2024.117190"
COMMENT     Sequence Label: BCL2alpha-MJK2243
FEATURES             Location/Qualifiers
     source          1..720
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggcgcacg ctgggagaac agggtacgat aaccgggaga tagtgatgaa gtacatccat
       61 tataagctgt cgcagagggg ctacgagtgg gatgcgggag atgtgggcgc cgcgcccccg
      121 ggggccgccc ccgcaccggg catcttctcc tcccagcccg ggcacacgcc ccatccagcc
      181 gcatcccggg acccggtcgc caggacctcg ccgctgcaga ccccggctgc ccccggcgcc
      241 gccgcggggc ctgcgctcag cccggtgcca cctgtggtcc acctgaccct ccgccaggcc
      301 ggcgacgact tctcccgccg ctaccgccgc gacttcgccg agatgtccag ccagctgcac
      361 ctgacgccct tcaccgcgcg gggacgcttt gccacggtgg tggaggagct cttcagggac
      421 ggggtgaact gggggaggat tgtggccttc tttgagttcg gtggggtcat gtgtgtggag
      481 agcgtcaacc gggagatgtc gcccctggtg gacaacatcg ccctgtggat gactgagtac
      541 ctgaaccggc acctgcacac ctggatccag gataacggag gctgggatgc ctttgtggaa
      601 ctgtacggcc ccagcatgcg gcctctgttt gatttctcct ggctgtctct gaagactctg
      661 ctcagtttgg ccctggtggg agcttgcatc accctgggtg cctatctggg ccacaagtga
//
