LOCUS       sequence-76794-e         814 bp    DNA     linear   UNA 15-APR-2025
DEFINITION  Expresses a TALE-TET1FL (full length TET1) fusion protein engineered
            to bind a site in the human KLF4 gene and demethylate CpGs adjacent 
            to the binding site.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 814)
  AUTHORS   Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai 
            SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson 
            MF, Joung JK
  TITLE     Targeted DNA demethylation and activation of endogenous genes using 
            programmable TALE-TET1 fusion proteins.
  JOURNAL   Nat Biotechnol. 2013 Oct 9. doi: 10.1038/nbt.2726.
  PUBMED    24108092
REFERENCE   2  (bases 1 to 814)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Apr 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Nat 
            Biotechnol. 2013 Oct 9. doi: 10.1038/nbt.2726."
COMMENT     Sequence Label: SL357
FEATURES             Location/Qualifiers
     source          1..814
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 tgccgcacgc gccggccttg atcaaaagaa ccaatcgccg tattcccgaa cgcacatccc
       61 atcgcgttgc cgaccacgcg caagtggttc gcgtgctggg ttttttccag tgccactccc
      121 acccagcgca agcatttgat gacgccatga cgcagttcgg gatgagcgga ggaggatcca
      181 tgtctcgatc ccgccatgca aggccttcca gattagtcag gaaggaagat gtaaacaaaa
      241 aaaagaaaaa cagccaacta cgaaagacaa ccaagggagc caacaaaaat gtggcatcag
      301 tcaagacttt aagccctgga aaattaaagc aattaattca agaaagagat gttaagaaaa
      361 aaacagaacc taaaccaccc gtgccagtca gaagccttct gacaagagct ggagcagcac
      421 gcatgaattt ggataggact gaggttcttt ttcagaaccc agagtcctta acctgcaatg
      481 ggtttacaat ggcgctacga agcacctctc ttagcaggcg actctcccaa cccccactgg
      541 tcgtagccaa atccaaaaag gttccacttt ctaagggttt agaaaagcaa catgattgtg
      601 attataagat actccctgct ttgggagtaa agcactcaga aaatgattcg gttccaatgc
      661 aagacaccca agtccttcct gatatagaga ctctaattgg tgtacaaaat ccctctttac
      721 ttaaaggtaa gagccaagag acaactcagt tttggtccca aagagttgag gattccaaga
      781 tcaatatccc tacccacagt ggccctgcag ctga
//
