LOCUS       sequence-11057-e        2451 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2451)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2451)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-HIPK1
FEATURES             Location/Qualifiers
     source          1..2451
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggttttga tgtttcagat tcgttatatt tcacaaacac aaggcttgcc agctgaatat
       61 cttctcagtg ccggaacaaa aacaaccagg tttttcaaca gagatcctaa tttggggtac
      121 ccactgtgga ggcttaagac acctgaagaa catgaactgg agactggaat aaaatcaaaa
      181 gaagctcgga agtacatttt taattgctta gatgacatgg ctcaggtgaa tatgtctacg
      241 gacctggagg gaacagacat gttggcagag aaggcagacc gaagagaata cattgatctg
      301 ttaaagaaaa tgctcacaat tgatgcagat aagagaatta cccctctaaa aactcttaac
      361 catcagtttg tgacaatgac tcaccttttg gattttccac atagcaatca tgttaagtct
      421 tgttttcaga acatggagat ctgcaagcgg agggttcaca tgtatgatac agtgagtcag
      481 atcaagagtc ccttcactac acatgttgcc ccaaatacaa gcacaaatct aaccatgagc
      541 ttcagcaatc agctcaatac agtgcacaat caggccagtg ttctagcttc cagttctact
      601 gcagcagctg ctactctttc tctggctaat tcagatgtct cactactaaa ctaccagtca
      661 gctttgtacc catcatctgc tgcaccagtt cctggagttg cccagcaggg tgtttccttg
      721 cagcctggaa ccacccagat ttgcactcag acagatccat tccaacagac atttatagta
      781 tgtccacctg cgtttcaaac tggactacaa gcaacaacaa agcattctgg attccctgtg
      841 aggatggata atgctgtacc aattgtaccc caggcaccag ctgctcagcc actacagatt
      901 cagtcaggag ttctcacgca gggaagctgt acaccactaa tggtagcaac tctccaccct
      961 caagtagcca ccatcacacc gcagtatgcg gtgcccttta ctctgagctg cgcagccggc
     1021 cggccggcgc tggttgaaca gactgccgct gtactgcagg cgtggcctgg agggactcag
     1081 caaattctcc tgccttcaac ttggcaacag ttgcctgggg tagctctaca caactctgtc
     1141 cagcccacag caatgattcc agaggccatg gggagtggac agcagctagc tgactggagg
     1201 aatgcccact ctcatggcaa ccagtacagc actatcatgc agcagccatc cttgctgact
     1261 aaccatgtga cattggccac tgctcagcct ctgaatgttg gtgttgccca tgttgtcaga
     1321 caacaacaat ccagttccct cccttcgaag aagaataagc agtcagctcc agtctcttcc
     1381 aagtcctctc tagatgttct gccttcccaa gtctattctc tggttgggag cagtcccctc
     1441 cgcaccacat cttcttataa ttccttggtc cctgtccaag atcagcatca gcccatcatc
     1501 attccagata ctcccagccc tcctgtgagt gtcatcacta tccgaagtga cactgatgag
     1561 gaagaggaca acaaatacaa gcccagtagc tctggactga agccaaggtc taatgtcatc
     1621 agttatgtca ctgtcaatga ttctcctgac tctgactctt ctttgagcag cccttattcc
     1681 actgataccc tgagtgctct ccgaggcaat agtggatccg ttttggaggg gcctggcaga
     1741 gttgtggcag atggcactgg cacccgcact atcattgtgc ctccactgaa aactcagctt
     1801 ggtgactgca ctgtagcaac ccaggcctca ggtctcctga gcaataagac taagccagtc
     1861 gcttcagtga gtgggcagtc atctggatgc tgtatcaccc ccacagggta tcgagctcaa
     1921 cgcgggggga ccagtgcagc acaaccactc aatcttagcc agaaccagca gtcatcggtg
     1981 gctccaacct cacaggagag aagcagcaac ccagcccccc gcaggcagca ggcgtttgtg
     2041 gcccctctct cccaagcccc ctacaccttc cagcatggca gcccgctaca ctcgacaggg
     2101 cacccacacc ttgccccggc ccctgctcac ctgccaagcc aggctcatct gtatacgtat
     2161 gctgccccga cttctgctgc tgcactgggc tcaaccagct ccattgctca tcttttctcc
     2221 ccacagggtt cctcaaggca tgctgcagcc tataccactc accctagcac tttggtgcac
     2281 caggtccctg tcagtgttgg gcccagcctc ctcacttctg ccagcgtggc ccctgctcag
     2341 taccaacacc agtttgccac ccaatcctac attgggtctt cccgaggctc aacaatttac
     2401 actggatacc cgctgagtcc taccaagatc agccagtatt cctacttata g
//
