LOCUS       sequence-11077-e        1947 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1947)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1947)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-RAF1
FEATURES             Location/Qualifiers
     source          1..1947
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggagcaca tacagggagc ttggaagacg atcagcaatg gttttggatt caaagatgcc
       61 gtgtttgatg gctccagctg catctctcct acaatagttc agcagtttgg ctatcagcgc
      121 cgggcatcag atgatggcaa actcacagat ccttctaaga caagcaacac tatccgtgtt
      181 ttcttgccga acaagcaaag aacagtggtc aatgtgcgaa atggaatgag cttgcatgac
      241 tgccttatga aagcactcaa ggtgaggggc ctgcaaccag agtgctgtgc agtgttcaga
      301 cttctccacg aacacaaagg taaaaaagca cgcttagatt ggaatactga tgctgcgtct
      361 ttgattggag aagaacttca agtagatttc ctggatcatg ttcccctcac aacacacaac
      421 tttgctcgga agacgttcct gaagcttgcc ttctgtgaca tctgtcagaa attcctgctc
      481 aatggatttc gatgtcagac ttgtggctac aaatttcatg agcactgtag caccaaagta
      541 cctactatgt gtgtggactg gagtaacatc agacaactct tattgtttcc aaattccact
      601 attggtgata gtggagtccc agcactacct tctttgacta tgcgtcgtat gcgagagtct
      661 gtttccagga tgcctgttag ttctcagcac agatattcta cacctcacgc cttcaccttt
      721 aacacctcca gtccctcatc tgaaggttcc ctctcccaga ggcagaggtc gacatccaca
      781 cctaatgtcc acatggtcag caccaccctg cctgtggaca gcaggatgat tgaggatgca
      841 attcgaagtc acagcgaatc agcctcacct tcagccctgt ccagtagccc caacaatctg
      901 agcccaacag gctggtcaca gccgaaaacc cccgtgccag cacaaagaga gcgggcacca
      961 gtatctggga cccaggagaa aaacaaaatt aggcctcgtg gacagagaga ttcaagctat
     1021 tattgggaaa tagaagccag tgaagtgatg ctgtccactc ggattgggtc aggctctttt
     1081 ggaactgttt ataagggtaa atggcacgga gatgttgcag taaagatcct aaaggttgtc
     1141 gacccaaccc cagagcaatt ccaggccttc aggaatgagg tggctgttct gcgcaaaaca
     1201 cggcatgtga acattctgct tttcatgggg tacatgacaa aggacaacct ggcaattgtg
     1261 acccagtggt gcgagggcag cagcctctac aaacacctgc atgtccagga gaccaagttt
     1321 cagatgttcc agctaattga cattgcccgg cagacggctc agggaatgga ctatttgcat
     1381 gcaaagaaca tcatccatag agacatgaaa tccaacaata tatttctcca tgaaggctta
     1441 acagtgaaaa ttggagattt tggtttggca acagtaaagt cacgctggag tggttctcag
     1501 caggttgaac aacctactgg ctctgtcctc tggatggccc cagaggtgat ccgaatgcag
     1561 gataacaacc cattcagttt ccagtcggat gtctactcct atggcatcgt attgtatgaa
     1621 ctgatgacgg gggagcttcc ttattctcac atcaacaacc gagatcagat catcttcatg
     1681 gtgggccgag gatatgcctc cccagatctt agtaagctat ataagaactg ccccaaagca
     1741 atgaagaggc tggtagctga ctgtgtgaag aaagtaaagg aagagaggcc tctttttccc
     1801 cagatcctgt cttccattga gctgctccaa cactctctac cgaagatcaa ccggagcgct
     1861 tccgagccat ccttgcatcg ggcagcccac actgaggata tcaatgcttg cacgctgacc
     1921 acgtccccga ggctgcctgt cttctag
//
