LOCUS       sequence-11092-e        1455 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1455)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-CLK1
FEATURES             Location/Qualifiers
     source          1..1455
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgagacact caaagagaac ttactgtcct gattgggatg acaaggattg ggattatgga
       61 aaatggagga gcagcagcag tcataaaaga aggaagagat cacatagcag tgcccaggag
      121 aacaagcgct gcaaatacaa tcactctaaa atgtgtgata gccattattt ggaaagcagg
      181 tctataaatg agaaagatta tcatagtcga cgctacattg atgagtacag aaatgactac
      241 actcaaggat gtgaacctgg acatcgccaa agagaccatg aaagccggta tcagaaccat
      301 agtagcaagt cttctggtag aagtggaaga agtagttata aaagcaaaca caggattcac
      361 cacagtactt cacatcgtcg ttcacatggg aagagtcacc gaaggaaaag aaccaggagt
      421 gtagaggatg atgaggaggg tcacctgatc tgtcagagtg gagacgtact aagtgcaaga
      481 tatgaaattg ttgatacttt aggtgaagga gcttttggaa aagttgtgga gtgcatcgat
      541 cataaagcgg gaggtagaca tgtagcagta aaaatagtta aaaatgtgga tagatactgt
      601 gaagctgctc gctcagaaat acaagttctg gaacatctga atacaacaga ccccaacagt
      661 actttccgct gtgtccagat gttggaatgg tttgagcatc atggtcacat ttgcattgtt
      721 tttgaactat tgggacttag tacttacgac ttcattaaag aaaatggttt tctaccattt
      781 cgactggatc atatcagaaa gatggcatat cagatatgca agtctgtgaa ttttttgcac
      841 agtaataagt tgactcacac agacttaaag cctgaaaaca tcttatttgt gcagtctgac
      901 tacacagagg cgtataatcc caaaataaaa cgtgatgaac gcaccttaat aaatccagat
      961 attaaagttg tagactttgg tagtgcaaca tatgatgacg aacatcacag tacattggta
     1021 tctacaagac attatagagc acctgaagtt attttagccc tagggtggtc ccaaccatgt
     1081 gatgtctgga gcataggatg cattcttatt gaatactatc ttgggtttac cgtatttcca
     1141 acacacgata gtaaggagca tttagcaatg atggaaagga ttcttggacc tctaccaaaa
     1201 catatgatac agaaaaccag gaaacgtaaa tattttcacc acgatcgatt agactgggat
     1261 gaacacagtt ctgccggcag atatgtttca agacgctgta aacctctgaa ggaatttatg
     1321 ctttctcaag atgttgaaca tgagcgtctc tttgacctca ttcagaaaat gttggagtat
     1381 gatccagcca aaagaattac tctcagagaa gccttaaagc atcctttctt tgaccttctg
     1441 aagaaaagta tatag
//
