LOCUS       sequence-11236-e        2466 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2466)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2466)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-FER
FEATURES             Location/Qualifiers
     source          1..2466
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggggtttg ggagtgacct gaagaattca catgaagcag tgttaaaatt gcaagactgg
       61 gaattacggt tactggaaac agtaaagaaa tttatggccc tgagaataaa aagtgataaa
      121 gaatatgcat ctactttaca gaacctttgt aatcaagttg ataaggaaag tactgtccaa
      181 atgaattatg tcagcaacgt atccaagtct tggctactta tgattcagca gacagaacaa
      241 cttagtagga taatgaagac acatgcagag gacttgaact ctggaccttt acacaggctc
      301 accatgatga ttaaggacaa gcagcaggtg aagaaaagtt acataggtgt tcatcagcag
      361 atagaggcag agatgatcaa ggttaccaaa acagaattgg agaagttaaa atgcagctat
      421 agacaattaa taaaagaaat gaattctgcc aaagagaaat ataaagaagc tttagctaaa
      481 gggaaggaaa ctgaaaaggc caaggaacga tacgacaaag ccacaatgaa acttcatatg
      541 ttgcacaatc agtatgtatt ggcgttgaaa ggggcacagc tccatcagaa tcagtattat
      601 gatatcacac ttcccctgct tctggactcc ttacaaaaga tgcaagaaga aatgataaaa
      661 gcactcaaag gtatatttga tgaatacagc cagataacca gtcttgtcac agaggaaata
      721 gtgaatgtcc ataaagagat tcaaatgtcg gttgaacaga tagatcctag tacagaatac
      781 aataatttca tagatgttca cagaacaacg gctgctaaag aacaagaaat agagtttgat
      841 acttccttac tggaagaaaa tgaaaatctt caggcaaatg agatcatgtg gaataactta
      901 acagcagaaa gtttgcaagt aatgttgaaa acgttagcgg aagaacttat gcaaacacag
      961 cagatgcttt taaacaagga ggaggctgtt ttggagttag agaagagaat tgaagaatct
     1021 tctgaaactt gtgagaagaa gtctgatatt gtgcttctgc taagccaaaa acaggcactt
     1081 gaagaactga aacagtcagt ccagcagctg agatgcactg aagcaaagtt ttcagcacag
     1141 aaggaattac tagagcaaaa agtgcaagaa aatgatggga aagagccacc tccagtagta
     1201 aattatgaag aagatgcacg atcagttaca tctatggaaa gaaaggagag gctatccaaa
     1261 tttgaatcta ttcgtcattc aattgctgga ataattaggt ctccaaaatc tgcactgggc
     1321 tcttcagcac tttctgatat gatctccatc agtgagaagc ctttggcaga acaggactgg
     1381 taccatggtg caattcccag aatagaagct caagaactgt taaaaaaaca aggagacttt
     1441 ttggtgcgag agagtcatgg gaaacctggt gaatatgtcc tttctgtata ttctgatgga
     1501 cagaggagac attttatcat acaatatgtt gataacatgt atcgattcga gggcactggg
     1561 ttttcaaaca ttcctcaact tatagatcat cactatacaa caaaacaggt catcactaag
     1621 aaatcaggtg tagttctgct gaatcctatt cctaaggaca agaaatggat tctcagtcat
     1681 gaagatgtca tattgggaga attactgggc aagggaaatt ttggtgaagt atataagggc
     1741 acattaaagg ataaaacttc tgttgctgtt aaaacatgta aagaagatct tcctcaggaa
     1801 ttgaaaataa aatttttaca agaagccaaa attctcaagc aatatgatca tcccaatatt
     1861 gtcaaactta taggagtttg cacacaaaga cagcctgtct acatcattat ggaactggtt
     1921 tcaggaggtg atttcctcac ctttctgaga aggaagaagg atgaactaaa actcaaacag
     1981 ttagtgaaat tttcattaga cgctgctgct ggtatgttgt atctcgagag taaaaactgt
     2041 atacacaggg accttgctgc aagaaactgc ctggtaggtg aaaataatgt tctgaaaatc
     2101 agtgactttg gaatgtctcg tcaagaggat ggtggagtgt attcatcttc tggcttaaag
     2161 cagattccca ttaaatggac agcaccggaa gctcttaatt atgggagata cagttcagag
     2221 agtgacgtgt ggagctttgg catccttctc tgggagacct tcagcttagg ggtttgtccg
     2281 taccctggaa tgacaaatca gcaagcaaga gagcaagtag aaagaggata ccggatgtca
     2341 gctccccagc actgtccaga ggatatttcc aaaatcatga tgaagtgttg ggattataaa
     2401 cctgaaaatc gccctaagtt cagtgaactt cagaaagagc tcactatcat caagagaaaa
     2461 ctcaca
//
