LOCUS       sequence-120738-         379 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  In addition to the mutations in alpha-s(alpha3beta5), this dominant 
            negative G protein alpha-s mutant contains the G226A mutation, which
            impairs activating conformation changes in Switch II..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 379)
  AUTHORS   Berlot CH
  TITLE     A highly effective dominant negative alpha s construct containing 
            mutations that affect distinct functions inhibits multiple 
            Gs-coupled receptor signaling pathways.
  JOURNAL   J Biol Chem. 2002 Jun 7;277(23):21080-5. Epub 2002 Apr 1.
  PUBMED    11927592
REFERENCE   2  (bases 1 to 379)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "J Biol 
            Chem."; date: "2002-06-7"; volume: "277(23)"; pages: "21080-5. Epub 
            2002 Apr 1"
COMMENT     Sequence Label: G protein alpha-s(alpha3beta5/G226A)
FEATURES             Location/Qualifiers
     source          1..379
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 aactttgact tcccacctga attctatgag catgccaagg ctctgtggga ggatgaggga
       61 gttcgtgcct gctacgagcg ctccaacgag taccagctga tcgactgtgc ccagtacttc
      121 ctggacaaga ttgatgtgat caagcaggcc gagtacatgc cgactgagca ggacctgctt
      181 cgctgccgcg tcctgacctc tggaatcttt gagaccaagt tccaggtgga caaagtcaac
      241 ttccacatgt tcgatgtggg cgcccagcgc gatgaacgcc gcaagtggat tcagtgcttc
      301 aatgatgtga ctgccatcat cttcgtggtg gccagcagca gctacaacat ggtcatccgg
      361 gaggacaacc agaccaacc
//
