LOCUS       sequence-129466-         863 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  encodes a Progerin mutant with serine 22 mutated to an alanine and 
            with a substitution of cysteine in CaaX-motif by a serine.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 863)
  AUTHORS   Moiseeva O, Lessard F, Acevedo-Aquino M, Vernier M, Tsantrizos YS, 
            Ferbeyre G
  TITLE     Mutant lamin A links prophase to a p53 independent senescence 
            program.
  JOURNAL   Cell Cycle. 2015 Aug 3;14(15):2408-21. doi: 
            10.1080/15384101.2015.1053671. Epub 2015 Jun 1.
  PUBMED    26029982
REFERENCE   2  (bases 1 to 863)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1080/15384101.2015.1053671"; journalName: "Cell Cycle"; date: 
            "2015-08-3- 3"; volume: "14"; issue: "15"; pages: "2408-21"
COMMENT     Sequence Label: pLPC-S22AProgerin-CS
FEATURES             Location/Qualifiers
     source          1..863
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atcttttatt ttatcggccc tctagatgca tgctcgagtt acatgatgct gctgttctgg
       61 gggctctggg ctcctgagcc gctggcagat gccttgtcgg caggctgccc gcaggtcccg
      121 cacagcacgg tgcgcgagcg caggttgtac tcagcggggt cccccgagct gctgcagtgg
      181 gagccgtggt ggtgatggag caggtcatct ccatcctcat cctcgtcgtc ctcaaccaca
      241 gtcactgagc gcaccagctt gcgcatggcc acttcttccc cagtggagtt gatgagagcc
      301 gtacgcaggc tgttcccgca gccccaggtg ttctgtgcct tccacaccag gtcggtaggg
      361 gggctgtggg tggccccagc tcctgcagcc cagatcgtca ccacctgccc agccttcagg
      421 gtgaactttg gtgggaaccg gtaagtcagc aagggatcat ctccattctg gcgcttgatc
      481 tgccaattgc ccatggactg gtcctcattg gacttgttgc gcagccggac aaacttgccc
      541 tcctcatcca cctcctccac ggccacgcgc ccgctagtgc gtgcgtgctg tgagaagctg
      601 ctgcggctct cagtggactc cagtttgcgc tttttggtga cgctgccccc accctgtgtc
      661 tgggatgagt gagaggaagc acggccacgg ctgcgctgcg aggtagggct gggggacagg
      721 cgtagcctct cctcctcgcc ctccaagagc ttgcggtagg cgtggatctc catgtccagg
      781 gccagcttga tgtccagaag ctcctggtac tcgtccagct gctgctgcat ccttgcccgc
      841 atctcggcca tctcccgctc ctt
//
