LOCUS       sequence-134618-         850 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Plasmid for testing 5'UTR TE Down (G-quadruplex) folding elements.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 850)
  AUTHORS   Wolfe AL, Singh K, Zhong Y, Drewe P, Rajasekhar VK, Sanghvi VR, 
            Mavrakis KJ, Jiang M, Roderick JE, Van der Meulen J, Schatz JH, 
            Rodrigo CM, Zhao C, Rondou P, de Stanchina E, Teruya-Feldstein J, 
            Kelliher MA, Speleman F, Porco JA Jr, Pelletier J, Ratsch G, Wendel 
            HG
  TITLE     RNA G-quadruplexes cause eIF4A-dependent oncogene translation in 
            cancer.
  JOURNAL   Nature. 2014 Sep 4;513(7516):65-70. doi: 10.1038/nature13485. Epub 
            2014 Jul 27.
  PUBMED    25079319
REFERENCE   2  (bases 1 to 850)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1038/nature13485"; journalName: "Nature"; date: "2014-09-4- 4"; 
            volume: "513"; issue: "7516"; pages: "65-70"
COMMENT     Sequence Label: PGL4-4X TE Down (GQs) Renilla
FEATURES             Location/Qualifiers
     source          1..850
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     regulatory      189..198
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
ORIGIN
        1 gcctcggcct ctgagctatt ccagaagtag tgaggaggct tttttggagg cctaggttga
       61 aagtactttg acggcggcgg cggtcaatct tacggcggcg gcggacatag atacggcggc
      121 ggcggtagaa actacggcgg cggcggatta gaatagtaaa agcttggcaa tccggtactg
      181 ttggtaaagc caccatggct tccaaggtgt acgaccccga gcaacgcaaa cgcatgatca
      241 ctgggcctca gtggtgggct cgctgcaagc aaatgaacgt gctggactcc ttcatcaact
      301 actatgattc cgagaagcac gccgagaacg ccgtgatttt tctgcatggt aacgctgcct
      361 ccagctacct gtggaggcac gtcgtgcctc acatcgagcc cgtggctaga tgcatcatcc
      421 ctgatctgat cggaatgggt aagtccggca agagcgggaa tggctcatat cgcctcctgg
      481 atcactacaa gtacctcacc gcttggttcg agctgctgaa ccttccaaag aaaatcatct
      541 ttgtgggcca cgactggggg gcttgtctgg cctttcacta ctcctacgag caccaagaca
      601 agatcaaggc catcgtccat gctgagagtg tcgtggacgt gatcgagtcc tgggacgagt
      661 ggcctgacat cgaggaggat atcgccctga tcaagagcga agagggcgag aaaatggtgc
      721 ttgagaataa cttcttcgtc gagaccatgc tcccaagcaa gatcatgcgg aaactggagc
      781 ctgaggagtt cgctgcctac ctggagccat tcaaggagaa gggcgaggtt agacggccta
      841 ccctctcctg
//
