LOCUS       sequence-135180-         890 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  activating MTOR mutation.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Grabiner BC, Nardi V, Birsoy K, Possemato R, Shen K, Sinha S, Jordan
            A, Beck AH, Sabatini DM
  TITLE     A diverse array of cancer-associated MTOR mutations are 
            hyperactivating and can predict rapamycin sensitivity.
  JOURNAL   Cancer Discov. 2014 May;4(5):554-63. doi: 
            10.1158/2159-8290.CD-13-0929. Epub 2014 Mar 14.
  PUBMED    24631838
REFERENCE   2  (bases 1 to 890)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1158/2159-8290.CD-13-0929"; journalName: "Cancer Discov"; date: 
            "2014-05"; volume: "4"; issue: "5"; pages: "554-63"
COMMENT     Sequence Label: pcDNA3-FLAG-MTOR-F1888L
FEATURES             Location/Qualifiers
     source          1..890
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 gaccgcagct ggtacaaggc ctggcatgcg tgggcagtga tgaacttcga agctgtgcta
       61 cactacaaac atcagaacca agcccgcgat gagaagaaga aactgcgtca tgccagcggg
      121 gccaacatca ccaacgccac cactgccgcc accacggccg ccactgccac caccactgcc
      181 agcaccgagg gcagcaacag tgagagcgag gccgagagca ccgagaacag ccccacccca
      241 tcgccgctgc agaagaaggt cactgaggat ctgtccaaaa ccctcctgat gtacacggtg
      301 cctgccgtcc agggcttatt ccgttccatc tccttgtcac gaggcaacaa cctccaggat
      361 acactcagag ttctcacctt atggtttgat tatggtcact ggccagatgt caatgaggcc
      421 ttagtggagg gggtgaaagc catccagatt gatacctggc tacaggttat acctcagctc
      481 attgcaagaa ttgatacgcc cagacccttg gtgggacgtc tcattcacca gcttctcaca
      541 gacattggtc ggtaccaccc ccaggccctc atctacccac tgacagtggc ttctaagtct
      601 accacgacag cccggcacaa tgcagccaac aagattctga agaacatgtg tgagcacagc
      661 aacaccctgg tccagcaggc catgatggtg agcgaggagc tgatccgagt ggccatcctc
      721 tggcatgaga tgtggcatga aggcctggaa gaggcatctc gtttgtactt tggggaaagg
      781 aacgtgaaag gcatgtttga ggtgctggag cccttgcatg ctatgatgga acggggcccc
      841 cagactctga aggaaacatc ctttaatcag gcctatggtc gagatttaat
//
