LOCUS       sequence-147085-         396 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  vector encoding both shRNA against CDK4(2) and shRNA against 
            CDK6(2).
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Acevedo M, Vernier M, Mignacca L, Lessard F, Huot G, Moiseeva O, 
            Bourdeau V, Ferbeyre G
  TITLE     A CDK4/6-Dependent Epigenetic Mechanism Protects Cancer Cells from 
            PML-induced Senescence.
  JOURNAL   Cancer Res. 2016 Jun 1;76(11):3252-64. doi: 
            10.1158/0008-5472.CAN-15-2347. Epub 2016 Mar 29.
  PUBMED    27206849
REFERENCE   2  (bases 1 to 396)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1158/0008-5472.CAN-15-2347"; journalName: "Cancer Res"; date: 
            "2016-06-1- 1"; volume: "76"; issue: "11"; pages: "3252-64"
COMMENT     Sequence Label: shCDK4/6(2)
FEATURES             Location/Qualifiers
     source          1..396
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     ncRNA           complement(13..139)
                     /label=3' miR-30a
                     /note="sequence downstream of the 71-nt precursor of the 
                     human miR-30a microRNA (Zeng et al., 2002)"
                     /ncRNA_class="miRNA"
     ncRNA           complement(167..181)
                     /label=miR-30a loop
                     /note="loop from the the 71-nt precursor of the human 
                     miR-30a microRNA (Zeng et al., 2002)"
                     /ncRNA_class="miRNA"
     ncRNA           complement(209..330)
                     /label=5' miR-30a
                     /note="sequence upstream of the 71-nt precursor of the 
                     human miR-30a microRNA (Zeng et al., 2002)"
                     /ncRNA_class="miRNA"
ORIGIN
        1 attggatcca aaaaagtgat ttaatttata ccattttaat tcagctttgt aaaaatgtat
       61 caaagagata gcaaggtatt cagttttagt aaacaagata attgctccta aagtagcccc
      121 ttgaattccg aggcagtagg caaccgagta gtgcatcgcg atcttacatc tgtggcttca
      181 ctaagatcgc gatgcactac tcggacgctc actgtcaaca gcaatatacc ttctcgagcc
      241 ttctgttggg ttaacctgaa gaagtaatcc cagcaagtgt ttccaagatg tgcaggcaac
      301 gattctgtaa agtactgaag cctcattcaa acaattaccc tgttatccct agtcgagaga
      361 tccaaaaaag tgatttaatt tataccattt taattc
//
