LOCUS       sequence-165943-        1039 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  luciferase reporter for mutant TERT promoter.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1039)
  AUTHORS   Bell RJ, Rube HT, Kreig A, Mancini A, Fouse SD, Nagarajan RP, Choi 
            S, Hong C, He D, Pekmezci M, Wiencke JK, Wrensch MR, Chang SM, Walsh
            KM, Myong S, Song JS, Costello JF
  TITLE     Cancer. The transcription factor GABP selectively binds and 
            activates the mutant TERT promoter in cancer.
  JOURNAL   Science. 2015 May 29;348(6238):1036-9. doi: 10.1126/science.aab0015.
            Epub 2015 May 14.
  PUBMED    25977370
REFERENCE   2  (bases 1 to 1039)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1126/science.aab0015"; journalName: "Science"; date: 
            "2015-05-29- 29"; volume: "348"; issue: "6238"; pages: "1036-9"
COMMENT     Sequence Label: pGL4.0-TERT G250A
FEATURES             Location/Qualifiers
     source          1..1039
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     regulatory      258..267
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
ORIGIN
        1 acatttctct ggcctaactg gccggtacct gagctcgcta gcctcgagtc ctgccccttc
       61 accttccagc tccgcctcct ccgcgcggac cccgccccgt cccgacccct tccgggtccc
      121 cggcccagcc ccctccgggc cctcccagcc cctccccttc ctttccgcgg ccccgccctc
      181 tcctcgcggc gcgagtttca ggcagcgctg gatctggcct cggcggccaa gcttggcaat
      241 ccggtactgt tggtaaagcc accatggaag atgccaaaaa cattaagaag ggcccagcgc
      301 cattctaccc actcgaagac gggaccgccg gcgagcagct gcacaaagcc atgaagcgct
      361 acgccctggt gcccggcacc atcgccttta ccgacgcaca tatcgaggtg gacattacct
      421 acgccgagta cttcgagatg agcgttcggc tggcagaagc tatgaagcgc tatgggctga
      481 atacaaacca tcggatcgtg gtgtgcagcg agaatagctt gcagttcttc atgcccgtgt
      541 tgggtgccct gttcatcggt gtggctgtgg ccccagctaa cgacatctac aacgagcgcg
      601 agctgctgaa cagcatgggc atcagccagc ccaccgtcgt attcgtgagc aagaaagggc
      661 tgcaaaagat cctcaacgtg caaaagaagc taccgatcat acaaaagatc atcatcatgg
      721 atagcaagac cgactaccag ggcttccaaa gcatgtacac cttcgtgact tcccatttgc
      781 cacccggctt caacgagtac gacttcgtgc ccgagagctt cgaccgggac aaaaccatcg
      841 ccctgatcat gaacagtagt ggcagtaccg gattgcccaa gggcgtagcc ctaccgcacc
      901 gcaccgcttg tgtccgattc agtcatgccc gcgaccccat cttcggcaac cagatcatcc
      961 ccgacaccgc tatcctcagc gtggtgccat ttcaccacgg cttcggcatg ttcaccacgc
     1021 tgggctactt gatctgcgg
//
