LOCUS       sequence-21718-e         851 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 851)
  AUTHORS   Freeman KW, Gangula RD, Welm BE, Ozen M, Foster BA, Rosen JM, 
            Ittmann M, Greenberg NM, Spencer DM
  TITLE     Conditional activation of fibroblast growth factor receptor (FGFR) 
            1, but not FGFR2, in prostate cancer cells leads to increased 
            osteopontin induction, extracellular signal-regulated kinase 
            activation, and in vivo proliferation.
  JOURNAL   Cancer Res. 2003 Oct 1. 63(19):6237-43.
  PUBMED    14559809
REFERENCE   2  (bases 1 to 851)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Cancer Res.
            2003 Oct 1. 63(19):6237-43."
COMMENT     Sequence Label: pSH1/M-FGFR2-Fv-Fvls-E
FEATURES             Location/Qualifiers
     source          1..851
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             complement(42..68)
                     /codon_start=1
                     /product="HA (human influenza hemagglutinin) epitope tag"
                     /label=HA
                     /translation="YPYDVPDYA"
     CDS             complement(93..413)
                     /codon_start=1
                     /product="F36V mutant of FK506-binding protein FKBP12"
                     /label=DmrB
                     /note="binds synthetic ligands that do not bind wild-type 
                     FKBP"
                     /translation="GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKVDSSRDRNKP
                     FKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELL
                     KLE"
ORIGIN
        1 gatatgntgg atcggtcatc aatcaggaat tcttagtcga gtgcgtagtc tggtacgtcg
       61 tacggatagt cgactccgga tccaccgcca gattccagtt ttagaagctc cacatcgaag
      121 acgagagtgg catgtggtgg gatgatgcct gggtgcccag tggcaccata ggcataatct
      181 ggagatatag tcagtttggc tctctgaccc acactcatct gggcaacccc ttcttcccag
      241 cctcggatca cctcctgctt gcctagcata aacttaaagg gcttgtttct gtcccgggag
      301 gaatcaactt tctttccatc ttcaagcatc ccggtgtagt gcaccacgca ggtctggccg
      361 cgcttgggga aggtgcgccc gtctcctggg gagatagtct ccacctgcac tccctcgact
      421 tccagtttta gaagctccac atcgaagacg agagtggcat gtggtgggat gatgcctggg
      481 tgcccagtgg caccataggc ataatctgga gatatagtca gtttggctct ctgacccaca
      541 ctcatctggg caaccccttc ttcccagcct cggatcacct cctgcttgcc tagcataaac
      601 ttaaagggct tgtttctgtc ccgggaggac atntcttacg nnnnnnnttc ancccccctg
      661 tgtagtgcac acgcagtctg gggcccccct tgggaagngc cccctctctg gggaaaaagt
      721 cccnctgcng cctccncgat gntaacctgc gttagngtga actgagcana aggttcaaag
      781 cnggnctgaa aaaaaaactc cngaaaaaaa ncttnggggn aaaaaaaaat taagggggga
      841 anatnttctt t
//
