LOCUS       sequence-252268-        5968 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  L1RP expression.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 5968)
  AUTHORS   Ardeljan D, Steranka JP, Liu C, Li Z, Taylor MS, Payer LM, Gorbounov
            M, Sarnecki JS, Deshpande V, Hruban RH, Boeke JD, Fenyo D, Wu PH, 
            Smogorzewska A, Holland AJ, Burns KH
  TITLE     Cell fitness screens reveal a conflict between LINE-1 
            retrotransposition and DNA replication.
  JOURNAL   Nat Struct Mol Biol. 2020 Feb;27(2):168-178. doi: 
            10.1038/s41594-020-0372-1. Epub 2020 Feb 10.
  PUBMED    32042151
REFERENCE   2  (bases 1 to 5968)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1038/s41594-020-0372-1"; journalName: "Nat Struct Mol Biol"; 
            date: "2020-02"; volume: "27"; issue: "2"; pages: "168-178"
COMMENT     Sequence Label: pDA077
FEATURES             Location/Qualifiers
     source          1..5968
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 ggccgcgggg ggaggagcca agatggccga ataggaacag ctccggtcta cagctcccag
       61 cgtgagcgac gcagaagacg gtgatttctg catttccatc tgaggtaccg ggttcatctc
      121 actagggagt gccagacagt gggcgcaggc cagtgtgtgt gcgcaccgtg cgcgagccga
      181 agcagggcga ggcattgcct cacctgggaa gcgcaagggg tcagggagtt ccctttccga
      241 gtcaaagaaa ggggtgacgg acgcacctgg aaaatcgggt cactcccacc cgaatattgc
      301 gcttttcaga ccggcttaag aaacggcgca ccacgagact atatcccgca cctggctcgg
      361 agggtcctac gcccacggaa tctcgctgat tgctagcaca gcagtctgag atcaaactgc
      421 aaggcggcaa cgaggctggg ggaggggcgc ccgccattgc ccaggcttgc ttaggtaaac
      481 aaagcagcag ggaagctcga actgggtgga gcccaccaca gctcaaggag gcctgcctgc
      541 ctctgtaggc tccacctctg ggggcagggc acagacaaac aaaaagacag cagtaacctc
      601 tgcagactta agtgtccctg tctgacagct ttgaagagag cagtggttct cccagcacgc
      661 agctggagat ctgagaacgg gcagactgcc tcctcaagtg ggtccctgac ccctgacccc
      721 cgagcagcct aactgggagg caccccccag caggggcaca ctgacacctc acacggcagg
      781 gtattccaac agacctgcag ctgagggtcc tgtctgttag aaggaaaact aacaaccaga
      841 aaggacatct acaccgaaaa cccatctgta catcaccatc atcaaagacc aaaagtagat
      901 aaaaccacaa agatggggaa aaaacagaac agaaaaactg gaaactctaa aacgcagagc
      961 gcctctcctc ctccaaagga acgcagttcc tcaccagcaa cagaacaaag ctggatggag
     1021 aatgattttg atgagctgag agaagaaggc ttcagacgat caaattactc tgagctacgg
     1081 gaggacattc aaaccaaagg caaagaagtt gaaaactttg aaaaaaattt agaagaatgt
     1141 ataactagaa taaccaatac agagaagtgc ttaaaggagc tgatggagct gaaaaccaag
     1201 gctcgagaac tacgtgaaga atgcagaagc ctcaggagcc gatgcgatca actggaagaa
     1261 agggtatcag caatggaaga tgaaatgaat gaaatgaagc gagaagggaa gtttagagaa
     1321 aaaagaataa aaagaaatga gcaaagcctc caagaaatat gggactatgt gaaaagacca
     1381 aatctacgtc tgattggtgt acctgaaagt gatgtggaga atggaaccaa gttggaaaac
     1441 actctgcagg atattatcca ggagaacttc cccaatctag caaggcaggc caacgttcag
     1501 attcaggaaa tacagagaac gccacaaaga tactcctcga gaagagcaac tccaagacac
     1561 ataattgtca gattcaccaa agttgaaatg aaggaaaaaa tgttaagggc agccagagag
     1621 aaaggtcggg ttaccctcaa aggaaagccc atcagactaa cagcggatct ctcggcagaa
     1681 accctacaag ccagaagaga gtgggggcca atattcaaca ttcttaaaga aaagaatttt
     1741 caacccagaa tttcatatcc agccaaacta agcttcataa gtgaaggaga aataaaatac
     1801 tttatagaca agcaaatgtt gagagatttt gtcaccacca ggcctgccct aaaagagctc
     1861 ctgaaggaag cgctaaacat ggaaaggaac aaccggtacc agccgctgca aaatcatgcc
     1921 aaaatgtaaa gaccatcaag actaggaaga aactgcacca actaatgagc aaaatcacca
     1981 gctaacatca taatgacagg atcaacttca cacataacaa tattaacttt aaatataaat
     2041 ggactaaatt ctgcaattaa aagacacaga ctggcaagtt ggataaagag tcaagaccca
     2101 tcagtgtgct gtattcagga aacccatctc acgtgcagag acacacatag gctcaaaata
     2161 aaaggatgga ggaagatcta ccaagccaat ggaaaacaaa aaaaggcagg ggttgcaatc
     2221 ctagtctctg ataaaacaga ctttaaacca acaaagatca aaagagacaa agaaggccat
     2281 tacataatgg taaagggatc aattcaacaa gaggagctaa ctatcctaaa tatttatgca
     2341 cccaatacag gagcacccag attcataaag caagtcctca gtgacctaca aagagactta
     2401 gactcccaca cattaataat gggagacttt aacaccccac tgtcaacatt agacagatca
     2461 acgagacaga aagtcaacaa ggatacccag gaattgaact cagctctgca ccaagcagac
     2521 ctaatagaca tctacagaac tctccacccc aaatcaacag aatatacgtt tttttcagca
     2581 ccacaccaca cctattccaa aattgaccac atagttggaa gcaaagctct cctcagcaaa
     2641 tgtaaaagaa cagaaattat aacaaactat ctctcagacc acagtgcaat caaactagag
     2701 ctcaggatta agaatctcac tcaaagccgc tcaactacat ggaaactgaa caacctgctc
     2761 ctgaatgact actgggtaca taacgaaatg aaggcagaaa taaagatgtt ctttgaaacc
     2821 aacgagaaca aagacaccac ataccagaat ctctgggacg cattcaaagc agtatgtaga
     2881 gggaaattta tagcactaaa tgcctacaag agaaagcagg aaagatccaa aattgacacc
     2941 ctaacatcac aattaaaaga actagaaaag caagagcaaa cacattcaaa agctagcaga
     3001 aggcaagaaa taactaaaat cagagcagaa ctgaaggaaa tagagacaca aaaaaccctt
     3061 caaaaaatca atgaatccag gagctggttt tttgaaagga tcaacaaaat tgatagaccg
     3121 ctagcaagac taataaagaa aaaaagagag aagaatcaaa tagacacaat aaaaaatgat
     3181 aaaggggata tcaccaccga tcccacagaa atacaaacta ccatcagaga atactacaaa
     3241 cacctctacg caaataaact agaaaatcta gaagaaatgg atacattcct cgacacatac
     3301 actctcccaa gactaaacca ggaagaagtt gaatctctga atcgaccaat aacaggctct
     3361 gaaattgtgg caataatcaa tagtttacca accaaaaaga gtccaggacc agatggattc
     3421 acagccgaat tctaccagag gtacaaggag gaactggtac cattccttct gaaactattc
     3481 caatcaatag aaaaagaggg aatcctccct aactcatttt atgaggccag catcattctg
     3541 ataccaaagc cgggcagaga cacaaccaaa aaagagaatt ttagaccaat atccttgatg
     3601 aacattgatg caaaaatcct caataaaata ctggcaaacc gaatccagca gcacatcaaa
     3661 aagcttatcc accatgatca agtgggcttc atccctggga tgcaaggctg gttcaatata
     3721 cgcaaatcaa taaatgtaat ccagcatata aacagagcca aagacaaaaa ccacatgatt
     3781 atctcaatag atgcagaaaa agcctttgac aaaattcaac aacccttcat gctaaaaact
     3841 ctcaataaat taggtattga tgggacgtat ttcaaaataa taagagctat ctatgacaaa
     3901 cccacagcca atatcatact gaatgggcaa aaactggaag cattcccttt gaaaaccggc
     3961 acaagacagg gatgccctct ctcaccgctc ctattcaaca tagtgttgga agttctggcc
     4021 agggcaatca ggcaggagaa ggaaataaag ggtattcaat taggaaaaga ggaagtcaaa
     4081 ttgtccctgt ttgcagacga catgattgtt tatctagaaa accccatcgt ctcagcccaa
     4141 aatctcctta agctgataag caacttcagc aaagtctcag gatacaaaat caatgtacaa
     4201 aaatcacaag cattcttata caccaacaac agacaaacag agagccaaat catgggtgaa
     4261 ctcccattca caattgcttc aaagagaata aaatacctag gaatccaact tacaagggat
     4321 gtgaaggacc tcttcaagga gaactacaaa ccactgctca aggaaataaa agaggagaca
     4381 aacaaatgga agaacattcc atgctcatgg gtaggaagaa tcaatatcgt gaaaatggcc
     4441 atactgccca aggtaattta cagattcaat gccatcccca tcaagctacc aatgactttc
     4501 ttcacagaat tggaaaaaac tactttaaag ttcatatgga accaaaaaag agcccgcatt
     4561 gccaagtcaa tcctaagcca aaagaacaaa gctggaggca tcacactacc tgacttcaaa
     4621 ctatactaca aggctacagt aaccaaaaca gcatggtact ggtaccaaaa cagagatata
     4681 gatcaatgga acagaacaga gccctcagaa ataatgccgc atatctacaa ctatctgatc
     4741 tttgacaaac ctgagaaaaa caagcaatgg ggaaaggatt ccctatttaa taaatggtgc
     4801 tgggaaaact ggctagccat atgtagaaag ctgaaactgg atcccttcct tacaccttat
     4861 acaaaaatca attcaagatg gattaaagat ttaaacgtta aacctaaaac cataaaaacc
     4921 ctagaagaaa acctaggcat taccattcag gacataggcg tgggcaagga cttcatgtcc
     4981 aaaacaccaa aagcaatggc aacaaaagac aaaattgaca aatgggatct aattaaacta
     5041 aagagcttct gcacagcaaa agaaactacc atcagagtga acaggcaacc tacaacatgg
     5101 gagaaaattt ttgcaaccta ctcatctgac aaagggctaa tatccagaat ctacaatgaa
     5161 ctcaaacaaa tttacaagaa aaaaacaaac aaccccatca aaaagtgggc gaaggacatg
     5221 aacagacact tctcaaaaga agacatttat gcagccaaaa aacacatgaa gaaatgctca
     5281 tcatcactgg ccatcagaga aatgcaaatc aaaaccacta tgagatatca tctcacacca
     5341 gttagaatgg caatcattaa aaagtcagga aacaacaggt gctggagagg atgcggagaa
     5401 ataggaacac ttttacactg ttggtgggac tgtaaactag ttcaaccatt gtggaagtca
     5461 gtgtggcgat tcctcaggga tctagaacta gaaataccat ttgacccagc catcccatta
     5521 ctgggtatat acccaaatga gtataaatca tgctgctata aagacacatg cacacgtatg
     5581 tttattgcgg cactattcac aatagcaaag acttggaacc aacccaaatg tccaacaatg
     5641 atagactgga ttaagaaaat gtggcacata tacaccatgg aatactatgc agccataaaa
     5701 aatgatgagt tcatatcctt tgtagggaca tggatgaaat tggaaaccat cattctcagt
     5761 aaactatcgc aagaacaaaa aaccaaacac cgcatattct cactcatagg tgggaattga
     5821 acaatgagat cacatggaca caggaagggg aatatcacac tctggggact gtggtggggt
     5881 cgggggaggg gggagggata gcattgggag atatacctaa tgctagatga cacattagtg
     5941 ggtgcagcgc accagcatgg cacatgta
//
