LOCUS       sequence-310043-        1080 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expresses murine Fbxw7 alpha in mammalian cells.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1080)
  AUTHORS   Gstalder C, Liu D, Miao D, Lutterbach B, DeVine AL, Lin C, Shettigar
            M, Pancholi P, Buchbinder EI, Carter SL, Manos MP, Rojas-Rudilla V, 
            Brennick R, Gjini E, Chen PH, Lako A, Rodig S, Yoon CH, Freeman GJ, 
            Barbie DA, Hodi FS, Miles W, Van Allen EM, Haq R
  TITLE     Inactivation of Fbxw7 impairs dsRNA sensing and confers resistance 
            to PD-1 blockade.
  JOURNAL   Cancer Discov. 2020 May 5. pii: 2159-8290.CD-19-1416. doi: 
            10.1158/2159-8290.CD-19-1416.
  PUBMED    32371478
REFERENCE   2  (bases 1 to 1080)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Cancer 
            Discov. 2020 May 5. pii: 2159-8290.CD-19-1416. doi: 
            10.1158/2159-8290.CD-19-1416."
COMMENT     Sequence Label: pENTR1A_mmFbxw7a (closed)
FEATURES             Location/Qualifiers
     source          1..1080
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    complement(974..1073)
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 tgcctacagt ttnnggcaac cgcatagtta gtggttntga tgacaacnct ttaaaagttt
       61 ggtcagcggt cacgggcaag tntctgagaa cgttagtggg acatacaggt ggagtgtggt
      121 catcacagat gagagacaat atcatcatca gtggatcgac tgaccggact ctcaaagtgt
      181 ggaatgctga aactggagag tgtatacata ctttatatgg gcacacttct actgtacggt
      241 gtatgcatct ccatgaaaaa agggttgtaa gcggttctcg agatgccact ctcagggttt
      301 gggatattga gaccggccag tgtttacacg tcctgatggg tcacgtagca gcggtccgct
      361 gcgttcagta tgatggcagg agggttgtta gtggagctta tgattttatg gtgaaggtgt
      421 gggatccaga gactgagacc tgtctacaca cgttacaggg acacactaat agagtctatt
      481 cattacagtt tgatggcatc catgtggtga gtggatctct tgatacatca atccgagtct
      541 gggatgtgga gacagggaat tgtattcaca cgctaacagg acaccagtca ttaacgagtg
      601 gaatggaact caaagacaat attcttgtct ctgggaatgc agattctaca gttaagatct
      661 gggatatcaa aacaggacag tgtttacaaa ctttgcaagg tcccagcaag catcagagcg
      721 ctgtgacctg cttacagttc aacaagaact tcgtaattac cagctcagac gacggaacgg
      781 tcaaactctg ggacttgaaa acgggtgaat ttatccgaaa cctcgtcaca ttggagagtg
      841 gggggagcgg gggagttgtg tggcggatca gggcctcaaa cacaaagctg gtgtgtgcag
      901 tcgggagtcg gaatggaact gaggaaacca agctcctggt gctggacttt gatgtggaca
      961 tgaaatgatc tagacccagc tttcttgtac aaagttggca ttataagaaa gcattgctta
     1021 tcaatttgtt gcaacgaaca ggtcactatc agtcaaaata aaatcattat tgccancnng
//
