LOCUS       sequence-350443-        1620 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  lentiviral transduction of human ZBTB7B gene with a point mutation 
            (R49H) in the BTB domain.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1620)
  AUTHORS   Lee WS, Lavery L, Rousseaux MWC, Rutledge EB, Jang Y, Wan YW, Wu SR,
            Kim W, Al-Ramahi I, Rath S, Adamski CJ, Bondar VV, Tewari A, 
            Soleimani S, Mota S, Yalamanchili HK, Orr HT, Liu Z, Botas J, Zoghbi
            HY
  TITLE     Dual targeting of brain region-specific kinases potentiates 
            neurological rescue in Spinocerebellar ataxia type 1.
  JOURNAL   EMBO J. 2021 Apr 1;40(7):e106106. doi: 10.15252/embj.2020106106. 
            Epub 2021 Mar 11.
  PUBMED    33709453
REFERENCE   2  (bases 1 to 1620)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "EMBO J."; 
            date: "2021-04-1"; volume: "40(7):e106106. doi"; pages: " 
            10.15252/embj.2020106106. Epub 2021 Mar 11"
COMMENT     Sequence Label: W118-1_hZBTB7B_R49H
FEATURES             Location/Qualifiers
     source          1..1620
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             complement(515..526)
                     /codon_start=1
                     /product="WELQut protease recognition and cleavage site"
                     /label=WELQut site
                     /translation="WELQ"
ORIGIN
        1 atggggagcc ccgaggatga cctgattggg attccattcc cggaccacag cagtgagctc
       61 ctgagctgcc tcaatgagca gcgccagctg ggccacctat gtgacctcac catccggacg
      121 cagggccttg aataccgcac ccaccacgct gtgctagctg cctgtagcca ctacttcaag
      181 aagcttttca ctgagggcgg tggcggagct gtcatggggg ccgggggtag cgggacggcc
      241 actgggggag caggggccgg tgtgtgtgag ctggactttg tagggccaga ggcactaggc
      301 gccctccttg aatttgccta tacagccaca ctgaccacca gcagcgccaa catgccagct
      361 gtgctccagg ctgcccgcct gctggagatc ccgtgtgtca tcgctgcttg catggagatt
      421 ctgcagggca gtgggctaga agctcccagc ccggacgagg atgactgtga gcgagcccgc
      481 cagtatctgg aggcctttgc cacagccacg gcctctggag ttcccaatgg tgaagacagt
      541 cctccacagg tgcccctccc accacctccg ccaccgccac ctcggcctgt tgcccgccgc
      601 agccgcaagc cccggaaagc tttcctgcaa accaaggggg ccagagcaaa ccacctagtc
      661 cctgaggtgc ccacagtgcc cgcccatccc ttgacctatg aggaggagga ggtggcgggc
      721 agagtgggca gcagtggggg cagtgggccg ggggacagct acagccctcc cacaggaact
      781 gcctcccctc ctgagggtcc ccagagctac gaaccctatg agggtgagga agaagaagag
      841 gagctggtat atcccccagc ctatgggctg gcgcagggtg gcgggccccc gctgtcccca
      901 gaggagctgg gctcagatga ggatgccatc gatcctgacc tgatggccta cctaagctcc
      961 ctgcaccagg acaacctggc accaggcctg gacagccaag acaagctggt gcgcaaacgc
     1021 cgctcccaga tgcctcagga gtgccctgtc tgccacaaga tcatccatgg ggcaggcaaa
     1081 ctgcctcgcc acatgaggac ccacacaggc gagaagccct ttgcctgcga ggtctgcggt
     1141 gttcgattca ccaggaacga caagctgaag atccacatgc ggaagcacac gggagagcgc
     1201 ccctactcat gcccgcactg cccagcccgc ttcctgcaca gctacgacct caagaaccac
     1261 atgcacctgc acacagggga ccggccctat gagtgccacc tgtgccacaa ggctttcgcc
     1321 aaggaggacc acctgcagcg ccacctcaaa ggccagaact gcctggaggt gcgcacccga
     1381 cggcgccgca aggacgatgc accaccccac tacccaccac cctctaccgc tgctgcatcc
     1441 cccgctggcc tcgacctctc caatggccac ctggacacct tccgcctctc tctagctcga
     1501 ttctgggagc agtcagcccc cactgggccc ccggtctcta ccccagggcc ccctgatgac
     1561 gatgaggagg aaggggcacc caccacaccc caggctgaag gtgccatgga gtcctcttag
//
