LOCUS       sequence-360081-       35000 bp    DNA     circular UNA 15-DEC-2025
DEFINITION  Adenoviral vector for XBP1s expression.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 35000)
  AUTHORS   Zeng L, Zampetaki A, Margariti A, Pepe AE, Alam S, Martin D, Xiao Q,
            Wang W, Jin ZG, Cockerill G, Mori K, Li YS, Hu Y, Chien S, Xu Q
  TITLE     Sustained activation of XBP1 splicing leads to endothelial apoptosis
            and atherosclerosis development in response to disturbed flow.
  JOURNAL   Proc Natl Acad Sci U S A. 2009 May 19;106(20):8326-31. doi: 
            10.1073/pnas.0903197106. Epub 2009 May 1.
  PUBMED    19416856
REFERENCE   2  (bases 1 to 35000)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1073/pnas.0903197106"; journalName: "Proc Natl Acad Sci U S A"; 
            date: "2009-05-19- 19"; volume: "106"; issue: "20"; pages: "8326-31"
COMMENT     Sequence Label: Ad-Flag-XBP1s
FEATURES             Location/Qualifiers
     source          1..35000
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     enhancer        1..380
                     /label=CMV enhancer
                     /note="human cytomegalovirus immediate early enhancer"
     promoter        381..584
                     /label=CMV promoter
                     /note="human cytomegalovirus (CMV) immediate early 
                     promoter"
     primer_bind     535..555
                     /label=CMV-F
                     /note="Human CMV immediate early promoter, forward primer"
     promoter        629..647
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
     CDS             670..693
                     /codon_start=1
                     /product="FLAG(R) epitope tag, followed by an enterokinase 
                     cleavage site"
                     /label=FLAG
                     /translation="DYKDDDDK"
     polyA_signal    1954..2035
                     /label=SV40 poly(A) signal
                     /note="SV40 polyadenylation signal"
     primer_bind     complement(1991..2010)
                     /label=SV40pA-R
                     /note="SV40 polyA, reverse primer"
     primer_bind     2045..2064
                     /label=EBV-rev
                     /note="SV40 polyA terminator, reverse primer"
     misc_feature    join(5653..5718,5719..5756)
                     /label=Ad SA
                     /note="adenovirus major late transcript splice acceptor 
                     (Friedrich and Soriano, 1991)"
     CDS             complement(12850..12861)
                     /codon_start=1
                     /product="Factor Xa recognition and cleavage site"
                     /label=Factor Xa site
                     /translation="IEGR"
     regulatory      20333..20342
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
     repeat_region   31302..31404
                     /label=ITR
                     /note="inverted terminal repeat of human adenovirus 
                     serotype 5"
     promoter        complement(31484..31502)
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
     primer_bind     complement(31509..31526)
                     /label=M13 Forward
                     /note="In lacZ gene. Also called M13-F20 or M13 (-21) 
                     Forward"
     primer_bind     complement(31509..31525)
                     /label=M13 fwd
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     complement(31518..31540)
                     /label=M13/pUC Forward
                     /note="In lacZ gene"
     rep_origin      complement(31666..32121)
                     /direction=LEFT
                     /label=f1 ori
                     /note="f1 bacteriophage origin of replication; arrow 
                     indicates direction of (+) strand synthesis"
     primer_bind     complement(31803..31824)
                     /label=F1ori-F
                     /note="F1 origin, forward primer"
     primer_bind     32015..32034
                     /label=F1ori-R
                     /note="F1 origin, reverse primer"
     promoter        32200..32304
                     /gene="bla"
                     /label=AmpR promoter
     CDS             join(32305..32373,32374..33165)
                     /codon_start=1
                     /gene="bla"
                     /product="beta-lactamase"
                     /label=AmpR
                     /note="confers resistance to ampicillin, carbenicillin, and
                     related antibiotics"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
     primer_bind     complement(32523..32542)
                     /label=Amp-R
                     /note="Ampicillin resistance gene, reverse primer"
     rep_origin      33336..33924
                     /direction=RIGHT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     primer_bind     33825..33844
                     /label=pBR322ori-F
                     /note="pBR322 origin, forward primer"
     primer_bind     34078..34095
                     /label=L4440
                     /note="L4440 vector, forward primer"
     protein_bind    34212..34233
                     /label=CAP binding site
                     /bound_moiety="E. coli catabolite activator protein"
                     /note="CAP binding activates transcription in the presence 
                     of cAMP."
     promoter        join(34248..34253,34254..34271,34272..34278)
                     /label=lac promoter
                     /note="promoter for the E. coli lac operon"
     protein_bind    34286..34302
                     /label=lac operator
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     primer_bind     34291..34313
                     /label=M13/pUC Reverse
                     /note="In lacZ gene"
     primer_bind     34310..34326
                     /label=M13 rev
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     34310..34326
                     /label=M13 Reverse
                     /note="In lacZ gene. Also called M13-rev"
     promoter        34344..34362
                     /label=SP6 promoter
                     /note="promoter for bacteriophage SP6 RNA polymerase"
     primer_bind     34344..34361
                     /label=SP6
                     /note="SP6 promoter, forward primer"
     repeat_region   34394..34496
                     /label=ITR
                     /note="inverted terminal repeat of human adenovirus 
                     serotype 5"
     misc_signal     34584..34734
                     /label=Ad5 Psi
                     /note="packaging signal for adenovirus serotype 5"
     primer_bind     complement(34810..34829)
                     /label=pRS-marker
                     /note="pRS vectors, use to sequence yeast selectable 
                     marker"
ORIGIN
        1 gacattgatt attgactagt tattaatagt aatcaattac ggggtcatta gttcatagcc
       61 catatatgga gttccgcgtt acataactta cggtaaatgg cccgcctggc tgaccgccca
      121 acgacccccg cccattgacg tcaataatga cgtatgttcc catagtaacg ccaataggga
      181 ctttccattg acgtcaatgg gtggagtatt tacggtaaac tgcccacttg gcagtacatc
      241 aagtgtatca tatgccaagt acgcccccta ttgacgtcaa tgacggtaaa tggcccgcct
      301 ggcattatgc ccagtacatg accttatggg actttcctac ttggcagtac atctacgtat
      361 tagtcatcgc tattaccatg gtgatgcggt tttggcagta catcaatggg cgtggatagc
      421 ggtttgactc acggggattt ccaagtctcc accccattga cgtcaatggg agtttgtttt
      481 ggcaccaaaa tcaacgggac tttccaaaat gtcgtaacaa ctccgcccca ttgacgcaaa
      541 tgggcggtag gcgtgtacgg tgggaggtct atataagcag agctctctgg ctaactagag
      601 aacccactgc ttactggctt atcgaaatta atacgactca ctatagggag acccaagctg
      661 gctagcatgg actacaagga cgacgatgac aaggaattca gatctggtac cctggtggtg
      721 gtggcagccg cgccgaaccc ggccgacggg acccctaaag ttctgcttct gtcggggcag
      781 cccgcctccg ccgccggagc cccggccggc caggccctgc cgctcatggt gccagcccag
      841 agaggggcca gcccggaggc agcgagcggg gggctgcccc aggcgcgcaa gcgacagcgc
      901 ctcacgcacc tgagccccga ggagaaggcg ctgaggagga aactgaaaaa cagagtagca
      961 gctcagactg ccagagatcg aaagaaggct cgaatgagtg agctggaaca gcaagtggta
     1021 gatttagaag aagagaacca aaaacttttg ctagaaaatc agcttttacg agagaaaact
     1081 catggccttg tagttgagaa ccaggagtta agacagcgct tggggatgga tgccctggtt
     1141 gctgaagagg aggcggaagc caaggggaat gaagtgaggc cagtggccgg gtctgctgag
     1201 tccgcagcag gtgcaggccc agttgtcacc cctccagaac atctccccat ggattctggc
     1261 ggtattgact cttcagattc agagtctgat atcctgttgg gcattctgga caacttggac
     1321 ccagtcatgt tcttcaaatg cccttcccca gagcctgcca gcctggagga gctcccagag
     1381 gtctacccag aaggacccag ttccttacca gcctcccttt ctctgtcagt ggggacgtca
     1441 tcagccaagc tggaagccat taatgaacta attcgttttg accacatata taccaagccc
     1501 ctagtcttag agataccctc tgagacagag agccaagcta atgtggtagt gaaaatcgag
     1561 gaagcacctc tcagcccctc agagaatgat caccctgaat tcattgtctc agtgaaggaa
     1621 gaacctgtag aagatgacct cgttccggag ctgggtatct caaatctgct ttcatccagc
     1681 cactgcccaa agccatcttc ctgcctactg gatgcttaca gtgactgtgg atacgggggt
     1741 tccctttccc cattcagtga catgtcctct ctgcttggtg taaaccattc ttgggaggac
     1801 acttttgcca atgaactctt tccccagctg attagtgtct aaggaatgat ccaatactgt
     1861 aagcttgcat gcctgcaggt cgactctaga ctcgagcggc cgccactgtg ctggatgatc
     1921 cgagctcggt accaagctta agtaagtgac tagaacttgt ttattgcagc ttataatggt
     1981 tacaaataaa gcaatagcat cacaaatttc acaaataaag catttttttc actgcattct
     2041 agttgtggtt tgtccaaact catctgcaga tctgaattca tctatgtcgg gtgcggagaa
     2101 agaggtaatg aaatggcatc gactcgaaga tctgggcgtg gttaagggtg ggaaagaata
     2161 tataaggtgg gggtcttatg tagttttgta tctgttttgc agcagccgcc gccgccatga
     2221 gcaccaactc gtttgatgga agcattgtga gctcatattt gacaacgcgc atgcccccat
     2281 gggccggggt gcgtcagaat gtgatgggct ccagcattga tggtcgcccc gtcctgcccg
     2341 caaactctac taccttgacc tacgagaccg tgtctggaac gccgttggag actgcagcct
     2401 ccgccgccgc ttcagccgct gcagccaccg cccgcgggat tgtgactgac tttgctttcc
     2461 tgagcccgct tgcaagcagt gcagcttccc gttcatccgc ccgcgatgac aagttgacgg
     2521 ctcttttggc acaattggat tctttgaccc gggaacttaa tgtcgtttct cagcagctgt
     2581 tggatctgcg ccagcaggtt tctgccctga aggcttcctc ccctcccaat gcggtttaaa
     2641 acataaataa aaaaccagac tctgtttgga tttggatcaa gcaagtgtct tgctgtcttt
     2701 atttaggggt tttgcgcgcg cggtaggccc gggaccagcg gtctcggtcg ttgagggtcc
     2761 tgtgtatttt ttccaggacg tggtaaaggt gactctggat gttcagatac atgggcataa
     2821 gcccgtctct ggggtggagg tagcaccact gcagagcttc atgctgcggg gtggtgttgt
     2881 agatgatcca gtcgtagcag gagcgctggg cgtggtgcct aaaaatgtct ttcagtagca
     2941 agctgattgc caggggcagg cccttggtgt aagtgtttac aaagcggtta agctgggatg
     3001 ggtgcatacg tggggatatg agatgcatct tggactgtat ttttaggttg gctatgttcc
     3061 cagccatatc cctccgggga ttcatgttgt gcagaaccac cagcacagtg tatccggtgc
     3121 acttgggaaa tttgtcatgt agcttagaag gaaatgcgtg gaagaacttg gagacgccct
     3181 tgtgacctcc aagattttcc atgcattcgt ccataatgat ggcaatgggc ccacgggcgg
     3241 cggcctgggc gaagatattt ctgggatcac taacgtcata gttgtgttcc aggatgagat
     3301 cgtcataggc catttttaca aagcgcgggc ggagggtgcc agactgcggt ataatggttc
     3361 catccggccc aggggcgtag ttaccctcac agatttgcat ttcccacgct ttgagttcag
     3421 atggggggat catgtctacc tgcggggcga tgaagaaaac ggtttccggg gtaggggaga
     3481 tcagctggga agaaagcagg ttcctgagca gctgcgactt accgcagccg gtgggcccgt
     3541 aaatcacacc tattaccggc tgcaactggt agttaagaga gctgcagctg ccgtcatccc
     3601 tgagcagggg ggccacttcg ttaagcatgt ccctgactcg catgttttcc ctgaccaaat
     3661 ccgccagaag gcgctcgccg cccagcgata gcagttcttg caaggaagca aagtttttca
     3721 acggtttgag accgtccgcc gtaggcatgc ttttgagcgt ttgaccaagc agttccaggc
     3781 ggtcccacag ctcggtcacc tgctctacgg catctcgatc cagcatatct cctcgtttcg
     3841 cgggttgggg cggctttcgc tgtacggcag tagtcggtgc tcgtccagac gggccagggt
     3901 catgtctttc cacgggcgca gggtcctcgt cagcgtagtc tgggtcacgg tgaaggggtg
     3961 cgctccgggc tgcgcgctgg ccagggtgcg cttgaggctg gtcctgctgg tgctgaagcg
     4021 ctgccggtct tcgccctgcg cgtcggccag gtagcatttg accatggtgt catagtccag
     4081 cccctccgcg gcgtggccct tggcgcgcag cttgcccttg gaggaggcgc cgcacgaggg
     4141 gcagtgcaga cttttgaggg cgtagagctt gggcgcgaga aataccgatt ccggggagta
     4201 ggcatccgcg ccgcaggccc cgcagacggt ctcgcattcc acgagccagg tgagctctgg
     4261 ccgttcgggg tcaaaaacca ggtttccccc atgctttttg atgcgtttct tacctctggt
     4321 ttccatgagc cggtgtccac gctcggtgac gaaaaggctg tccgtgtccc cgtatacaga
     4381 cttgagaggc ctgtcctcga gcggtgttcc gcggtcctcc tcgtatagaa actcggacca
     4441 ctctgagaca aaggctcgcg tccaggccag cacgaaggag gctaagtggg aggggtagcg
     4501 gtcgttgtcc actagggggt ccactcgctc cagggtgtga agacacatgt cgccctcttc
     4561 ggcatcaagg aaggtgattg gtttgtaggt gtaggccacg tgaccgggtg ttcctgaagg
     4621 ggggctataa aagggggtgg gggcgcgttc gtcctcactc tcttccgcat cgctgtctgc
     4681 gagggccagc tgttggggtg agtactccct ctgaaaagcg ggcatgactt ctgcgctaag
     4741 attgtcagtt tccaaaaacg aggaggattt gatattcacc tggcccgcgg tgatgccttt
     4801 gagggtggcc gcatccatct ggtcagaaaa gacaatcttt ttgttgtcaa gcttggtggc
     4861 aaacgacccg tagagggcgt tggacagcaa cttggcgatg gagcgcaggg tttggttttt
     4921 gtcgcgatcg gcgcgctcct tggccgcgat gtttagctgc acgtattcgc gcgcaacgca
     4981 ccgccattcg ggaaagacgg tggtgcgctc gtcgggcacc aggtgcacgc gccaaccgcg
     5041 gttgtgcagg gtgacaaggt caacgctggt ggctacctct ccgcgtaggc gctcgttggt
     5101 ccagcagagg cggccgccct tgcgcgagca gaatggcggt agggggtcta gctgcgtctc
     5161 gtccgggggg tctgcgtcca cggtaaagac cccgggcagc aggcgcgcgt cgaagtagtc
     5221 tatcttgcat ccttgcaagt ctagcgcctg ctgccatgcg cgggcggcaa gcgcgcgctc
     5281 gtatgggttg agtgggggac cccatggcat ggggtgggtg agcgcggagg cgtacatgcc
     5341 gcaaatgtcg taaacgtaga ggggctctct gagtattcca agatatgtag ggtagcatct
     5401 tccaccgcgg atgctggcgc gcacgtaatc gtatagttcg tgcgagggag cgaggaggtc
     5461 gggaccgagg ttgctacggg cgggctgctc tgctcggaag actatctgcc tgaagatggc
     5521 atgtgagttg gatgatatgg ttggacgctg gaagacgttg aagctggcgt ctgtgagacc
     5581 taccgcgtca cgcacgaagg aggcgtagga gtcgcgcagc ttgttgacca gctcggcggt
     5641 gacctgcacg tctagggcgc agtagtccag ggtttccttg atgatgtcat acttatcctg
     5701 tccctttttt ttccacagct cgcggttgag gacaaactct tcgcggtctt tccagtactc
     5761 ttggatcgga aacccgtcgg cctccgaacg gtaagagcct agcatgtaga actggttgac
     5821 ggcctggtag gcgcagcatc ccttttctac gggtagcgcg tatgcctgcg cggccttccg
     5881 gagcgaggtg tgggtgagcg caaaggtgtc cctgaccatg actttgaggt actggtattt
     5941 gaagtcagtg tcgtcgcatc cgccctgctc ccagagcaaa aagtccgtgc gctttttgga
     6001 acgcggattt ggcagggcga aggtgacatc gttgaagagt atctttcccg cgcgaggcat
     6061 aaagttgcgt gtgatgcgga agggtcccgg cacctcggaa cggttgttaa ttacctgggc
     6121 ggcgagcacg atctcgtcaa agccgttgat gttgtggccc acaatgtaaa gttccaagaa
     6181 gcgcgggatg cccttgatgg aaggcaattt tttaagttcc tcgtaggtga gctcttcagg
     6241 ggagctgagc ccgtgctctg aaagggccca gtctgcaaga tgagggttgg aagcgacgaa
     6301 tgagctccac aggtcacggg ccattagcat ttgcaggtgg tcgcgaaagg tcctaaactg
     6361 gcgacctatg gccatttttt ctggggtgat gcagtagaag gtaagcgggt cttgttccca
     6421 gcggtcccat ccaaggttcg cggctaggtc tcgcgcggca gtcactagag gctcatctcc
     6481 gccgaacttc atgaccagca tgaagggcac gagctgcttc ccaaaggccc ccatccaagt
     6541 ataggtctct acatcgtagg tgacaaagag acgctcggtg cgaggatgcg agccgatcgg
     6601 gaagaactgg atctcccgcc accaattgga ggagtggcta ttgatgtggt gaaagtagaa
     6661 gtccctgcga cgggccgaac actcgtgctg gcttttgtaa aaacgtgcgc agtactggca
     6721 gcggtgcacg ggctgtacat cctgcacgag gttgacctga cgaccgcgca caaggaagca
     6781 gagtgggaat ttgagcccct cgcctggcgg gtttggctgg tggtcttcta cttcggctgc
     6841 ttgtccttga ccgtctggct gctcgagggg agttacggtg gatcggacca ccacgccgcg
     6901 cgagcccaaa gtccagatgt ccgcgcgcgg cggtcggagc ttgatgacaa catcgcgcag
     6961 atgggagctg tccatggtct ggagctcccg cggcgtcagg tcaggcggga gctcctgcag
     7021 gtttacctcg catagacggg tcagggcgcg ggctagatcc aggtgatacc taatttccag
     7081 gggctggttg gtggcggcgt cgatggcttg caagaggccg catccccgcg gcgcgactac
     7141 ggtaccgcgc ggcgggcggt gggccgcggg ggtgtccttg gatgatgcat ctaaaagcgg
     7201 tgacgcgggc gagcccccgg aggtaggggg ggctccggac ccgccgggag agggggcagg
     7261 ggcacgtcgg cgccgcgcgc gggcaggagc tggtgctgcg cgcgtaggtt gctggcgaac
     7321 gcgacgacgc ggcggttgat ctcctgaatc tggcgcctct gcgtgaagac gacgggcccg
     7381 gtgagcttga acctgaaaga gagttcgaca gaatcaattt cggtgtcgtt gacggcggcc
     7441 tggcgcaaaa tctcctgcac gtctcctgag ttgtcttgat aggcgatctc ggccatgaac
     7501 tgctcgatct cttcctcctg gagatctccg cgtccggctc gctccacggt ggcggcgagg
     7561 tcgttggaaa tgcgggccat gagctgcgag aaggcgttga ggcctccctc gttccagacg
     7621 cggctgtaga ccacgccccc ttcggcatcg cgggcgcgca tgaccacctg cgcgagattg
     7681 agctccacgt gccgggcgaa gacggcgtag tttcgcaggc gctgaaagag gtagttgagg
     7741 gtggtggcgg tgtgttctgc cacgaagaag tacataaccc agcgtcgcaa cgtggattcg
     7801 ttgatatccc ccaaggcctc aaggcgctcc atggcctcgt agaagtccac ggcgaagttg
     7861 aaaaactggg agttgcgcgc cgacacggtt aactcctcct ccagaagacg gatgagctcg
     7921 gcgacagtgt cgcgcacctc gcgctcaaag gctacagggg cctcttcttc ttcttcaatc
     7981 tcctcttcca taagggcctc cccttcttct tcttctggcg gcggtggggg aggggggaca
     8041 cggcggcgac gacggcgcac cgggaggcgg tcgacaaagc gctcgatcat ctccccgcgg
     8101 cgacggcgca tggtctcggt gacggcgcgg ccgttctcgc gggggcgcag ttggaagacg
     8161 ccgcccgtca tgtcccggtt atgggttggc ggggggctgc catgcggcag ggatacggcg
     8221 ctaacgatgc atctcaacaa ttgttgtgta ggtactccgc cgccgaggga cctgagcgag
     8281 tccgcatcga ccggatcgga aaacctctcg agaaaggcgt ctaaccagtc acagtcgcaa
     8341 ggtaggctga gcaccgtggc gggcggcagc gggcggcggt cggggttgtt tctggcggag
     8401 gtgctgctga tgatgtaatt aaagtaggcg gtcttgagac ggcggatggt cgacagaagc
     8461 accatgtcct tgggtccggc ctgctgaatg cgcaggcggt cggccatgcc ccaggcttcg
     8521 ttttgacatc ggcgcaggtc tttgtagtag tcttgcatga gcctttctac cggcacttct
     8581 tcttctcctt cctcttgtcc tgcatctctt gcatctatcg ctgcggcggc ggcggagttt
     8641 ggccgtaggt ggcgccctct tcctcccatg cgtgtgaccc cgaagcccct catcggctga
     8701 agcagggcta ggtcggcgac aacgcgctcg gctaatatgg cctgctgcac ctgcgtgagg
     8761 gtagactgga agtcatccat gtccacaaag cggtggtatg cgcccgtgtt gatggtgtaa
     8821 gtgcagttgg ccataacgga ccagttaacg gtctggtgac ccggctgcga gagctcggtg
     8881 tacctgagac gcgagtaagc cctcgagtca aatacgtagt cgttgcaagt ccgcaccagg
     8941 tactggtatc ccaccaaaaa gtgcggcggc ggctggcggt agaggggcca gcgtagggtg
     9001 gccggggctc cgggggcgag atcttccaac ataaggcgat gatatccgta gatgtacctg
     9061 gacatccagg tgatgccggc ggcggtggtg gaggcgcgcg gaaagtcgcg gacgcggttc
     9121 cagatgttgc gcagcggcaa aaagtgctcc atggtcggga cgctctggcc ggtcaggcgc
     9181 gcgcaatcgt tgacgctcta gcgtgcaaaa ggagagcctg taagcgggca ctcttccgtg
     9241 gtctggtgga taaattcgca agggtatcat ggcggacgac cggggttcga gccccgtatc
     9301 cggccgtccg ccgtgatcca tgcggttacc gcccgcgtgt cgaacccagg tgtgcgacgt
     9361 cagacaacgg gggagtgctc cttttggctt ccttccaggc gcggcggctg ctgcgctagc
     9421 ttttttggcc actggccgcg cgcagcgtaa gcggttaggc tggaaagcga aagcattaag
     9481 tggctcgctc cctgtagccg gagggttatt ttccaagggt tgagtcgcgg gacccccggt
     9541 tcgagtctcg gaccggccgg actgcggcga acgggggttt gcctccccgt catgcaagac
     9601 cccgcttgca aattcctccg gaaacaggga cgagcccctt ttttgctttt cccagatgca
     9661 tccggtgctg cggcagatgc gcccccctcc tcagcagcgg caagagcaag agcagcggca
     9721 gacatgcagg gcaccctccc ctcctcctac cgcgtcagga ggggcgacat ccgcggttga
     9781 cgcggcagca gatggtgatt acgaaccccc gcggcgccgg gcccggcact acctggactt
     9841 ggaggagggc gagggcctgg cgcggctagg agcgccctct cctgagcggc acccaagggt
     9901 gcagctgaag cgtgatacgc gtgaggcgta cgtgccgcgg cagaacctgt ttcgcgaccg
     9961 cgagggagag gagcccgagg agatgcggga tcgaaagttc cacgcagggc gcgagctgcg
    10021 gcatggcctg aatcgcgagc ggttgctgcg cgaggaggac tttgagcccg acgcgcgaac
    10081 cgggattagt cccgcgcgcg cacacgtggc ggccgccgac ctggtaaccg catacgagca
    10141 gacggtgaac caggagatta actttcaaaa aagctttaac aaccacgtgc gtacgcttgt
    10201 ggcgcgcgag gaggtggcta taggactgat gcatctgtgg gactttgtaa gcgcgctgga
    10261 gcaaaaccca aatagcaagc cgctcatggc gcagctgttc cttatagtgc agcacagcag
    10321 ggacaacgag gcattcaggg atgcgctgct aaacatagta gagcccgagg gccgctggct
    10381 gctcgatttg ataaacatcc tgcagagcat agtggtgcag gagcgcagct tgagcctggc
    10441 tgacaaggtg gccgccatca actattccat gcttagcctg ggcaagtttt acgcccgcaa
    10501 gatataccat accccttacg ttcccataga caaggaggta aagatcgagg ggttctacat
    10561 gcgcatggcg ctgaaggtgc ttaccttgag cgacgacctg ggcgtttatc gcaacgagcg
    10621 catccacaag gccgtgagcg tgagccggcg gcgcgagctc agcgaccgcg agctgatgca
    10681 cagcctgcaa agggccctgg ctggcacggg cagcggcgat agagaggccg agtcctactt
    10741 tgacgcgggc gctgacctgc gctgggcccc aagccgacgc gccctggagg cagctggggc
    10801 cggacctggg ctggcggtgg cacccgcgcg cgctggcaac gtcggcggcg tggaggaata
    10861 tgacgaggac gatgagtacg agccagagga cggcgagtac taagcggtga tgtttctgat
    10921 cagatgatgc aagacgcaac ggacccggcg gtgcgggcgg cgctgcagag ccagccgtcc
    10981 ggccttaact ccacggacga ctggcgccag gtcatggacc gcatcatgtc gctgactgcg
    11041 cgcaatcctg acgcgttccg gcagcagccg caggccaacc ggctctccgc aattctggaa
    11101 gcggtggtcc cggcgcgcgc aaaccccacg cacgagaagg tgctggcgat cgtaaacgcg
    11161 ctggccgaaa acagggccat ccggcccgac gaggccggcc tggtctacga cgcgctgctt
    11221 cagcgcgtgg ctcgttacaa cagcggcaac gtgcagacca acctggaccg gctggtgggg
    11281 gatgtgcgcg aggccgtggc gcagcgtgag cgcgcgcagc agcagggcaa cctgggctcc
    11341 atggttgcac taaacgcctt cctgagtaca cagcccgcca acgtgccgcg gggacaggag
    11401 gactacacca actttgtgag cgcactgcgg ctaatggtga ctgagacacc gcaaagtgag
    11461 gtgtaccagt ctgggccaga ctattttttc cagaccagta gacaaggcct gcagaccgta
    11521 aacctgagcc aggctttcaa aaacttgcag gggctgtggg gggtgcgggc tcccacaggc
    11581 gaccgcgcga ccgtgtctag cttgctgacg cccaactcgc gcctgttgct gctgctaata
    11641 gcgcccttca cggacagtgg cagcgtgtcc cgggacacat acctaggtca cttgctgaca
    11701 ctgtaccgcg aggccatagg tcaggcgcat gtggacgagc atactttcca ggagattaca
    11761 agtgtcagcc gcgcgctggg gcaggaggac acgggcagcc tggaggcaac cctaaactac
    11821 ctgctgacca accggcggca gaagatcccc tcgttgcaca gtttaaacag cgaggaggag
    11881 cgcattttgc gctacgtgca gcagagcgtg agccttaacc tgatgcgcga cggggtaacg
    11941 cccagcgtgg cgctggacat gaccgcgcgc aacatggaac cgggcatgta tgcctcaaac
    12001 cggccgttta tcaaccgcct aatggactac ttgcatcgcg cggccgccgt gaaccccgag
    12061 tatttcacca atgccatctt gaacccgcac tggctaccgc cccctggttt ctacaccggg
    12121 ggattcgagg tgcccgaggg taacgatgga ttcctctggg acgacataga cgacagcgtg
    12181 ttttccccgc aaccgcagac cctgctagag ttgcaacagc gcgagcaggc agaggcggcg
    12241 ctgcgaaagg aaagcttccg caggccaagc agcttgtccg atctaggcgc tgcggccccg
    12301 cggtcagatg ctagtagccc atttccaagc ttgatagggt ctcttaccag cactcgcacc
    12361 acccgcccgc gcctgctggg cgaggaggag tacctaaaca actcgctgct gcagccgcag
    12421 cgcgaaaaaa acctgcctcc ggcatttccc aacaacggga tagagagcct agtggacaag
    12481 atgagtagat ggaagacgta cgcgcaggag cacagggacg tgccaggccc gcgcccgccc
    12541 acccgtcgtc aaaggcacga ccgtcagcgg ggtctggtgt gggaggacga tgactcggca
    12601 gacgacagca gcgtcctgga tttgggaggg agtggcaacc cgtttgcgca ccttcgcccc
    12661 aggctgggga gaatgtttta aaaaaaaaaa aagcatgatg caaaataaaa aactcaccaa
    12721 ggccatggca ccgagcgttg gttttcttgt attcccctta gtatgcggcg cgcggcgatg
    12781 tatgaggaag gtcctcctcc ctcctacgag agtgtggtga gcgcggcgcc agtggcggcg
    12841 gcgctgggtt ctcccttcga tgctcccctg gacccgccgt ttgtgcctcc gcggtacctg
    12901 cggcctaccg gggggagaaa cagcatccgt tactctgagt tggcacccct attcgacacc
    12961 acccgtgtgt acctggtgga caacaagtca acggatgtgg catccctgaa ctaccagaac
    13021 gaccacagca actttctgac cacggtcatt caaaacaatg actacagccc gggggaggca
    13081 agcacacaga ccatcaatct tgacgaccgg tcgcactggg gcggcgacct gaaaaccatc
    13141 ctgcatacca acatgccaaa tgtgaacgag ttcatgttta ccaataagtt taaggcgcgg
    13201 gtgatggtgt cgcgcttgcc tactaaggac aatcaggtgg agctgaaata cgagtgggtg
    13261 gagttcacgc tgcccgaggg caactactcc gagaccatga ccatagacct tatgaacaac
    13321 gcgatcgtgg agcactactt gaaagtgggc agacagaacg gggttctgga aagcgacatc
    13381 ggggtaaagt ttgacacccg caacttcaga ctggggtttg accccgtcac tggtcttgtc
    13441 atgcctgggg tatatacaaa cgaagccttc catccagaca tcattttgct gccaggatgc
    13501 ggggtggact tcacccacag ccgcctgagc aacttgttgg gcatccgcaa gcggcaaccc
    13561 ttccaggagg gctttaggat cacctacgat gatctggagg gtggtaacat tcccgcactg
    13621 ttggatgtgg acgcctacca ggcgagcttg aaagatgaca ccgaacaggg cgggggtggc
    13681 gcaggcggca gcaacagcag tggcagcggc gcggaagaga actccaacgc ggcagccgcg
    13741 gcaatgcagc cggtggagga catgaacgat catgccattc gcggcgacac ctttgccaca
    13801 cgggctgagg agaagcgcgc tgaggccgaa gcagcggccg aagctgccgc ccccgctgcg
    13861 caacccgagg tcgagaagcc tcagaagaaa ccggtgatca aacccctgac agaggacagc
    13921 aagaaacgca gttacaacct aataagcaat gacagcacct tcacccagta ccgcagctgg
    13981 taccttgcat acaactacgg cgaccctcag accggaatcc gctcatggac cctgctttgc
    14041 actcctgacg taacctgcgg ctcggagcag gtctactggt cgttgccaga catgatgcaa
    14101 gaccccgtga ccttccgctc cacgcgccag atcagcaact ttccggtggt gggcgccgag
    14161 ctgttgcccg tgcactccaa gagcttctac aacgaccagg ccgtctactc ccaactcatc
    14221 cgccagttta cctctctgac ccacgtgttc aatcgctttc ccgagaacca gattttggcg
    14281 cgcccgccag cccccaccat caccaccgtc agtgaaaacg ttcctgctct cacagatcac
    14341 gggacgctac cgctgcgcaa cagcatcgga ggagtccagc gagtgaccat tactgacgcc
    14401 agacgccgca cctgccccta cgtttacaag gccctgggca tagtctcgcc gcgcgtccta
    14461 tcgagccgca ctttttgagc aagcatgtcc atccttatat cgcccagcaa taacacaggc
    14521 tggggcctgc gcttcccaag caagatgttt ggcggggcca agaagcgctc cgaccaacac
    14581 ccagtgcgcg tgcgcgggca ctaccgcgcg ccctggggcg cgcacaaacg cggccgcact
    14641 gggcgcacca ccgtcgatga cgccatcgac gcggtggtgg aggaggcgcg caactacacg
    14701 cccacgccgc caccagtgtc cacagtggac gcggccattc agaccgtggt gcgcggagcc
    14761 cggcgctatg ctaaaatgaa gagacggcgg aggcgcgtag cacgtcgcca ccgccgccga
    14821 cccggcactg ccgcccaacg cgcggcggcg gccctgctta accgcgcacg tcgcaccggc
    14881 cgacgggcgg ccatgcgggc cgctcgaagg ctggccgcgg gtattgtcac tgtgcccccc
    14941 aggtccaggc gacgagcggc cgccgcagca gccgcggcca ttagtgctat gactcagggt
    15001 cgcaggggca acgtgtattg ggtgcgcgac tcggttagcg gcctgcgcgt gcccgtgcgc
    15061 acccgccccc cgcgcaacta gattgcaaga aaaaactact tagactcgta ctgttgtatg
    15121 tatccagcgg cggcggcgcg caacgaagct atgtccaagc gcaaaatcaa agaagagatg
    15181 ctccaggtca tcgcgccgga gatctatggc cccccgaaga aggaagagca ggattacaag
    15241 ccccgaaagc taaagcgggt caaaaagaaa aagaaagatg atgatgatga acttgacgac
    15301 gaggtggaac tgctgcacgc taccgcgccc aggcgacggg tacagtggaa aggtcgacgc
    15361 gtaaaacgtg ttttgcgacc cggcaccacc gtagtcttta cgcccggtga gcgctccacc
    15421 cgcacctaca agcgcgtgta tgatgaggtg tacggcgacg aggacctgct tgagcaggcc
    15481 aacgagcgcc tcggggagtt tgcctacgga aagcggcata aggacatgct ggcgttgccg
    15541 ctggacgagg gcaacccaac acctagccta aagcccgtaa cactgcagca ggtgctgccc
    15601 gcgcttgcac cgtccgaaga aaagcgcggc ctaaagcgcg agtctggtga cttggcaccc
    15661 accgtgcagc tgatggtacc caagcgccag cgactggaag atgtcttgga aaaaatgacc
    15721 gtggaacctg ggctggagcc cgaggtccgc gtgcggccaa tcaagcaggt ggcgccggga
    15781 ctgggcgtgc agaccgtgga cgttcagata cccactacca gtagcaccag tattgccacc
    15841 gccacagagg gcatggagac acaaacgtcc ccggttgcct cagcggtggc ggatgccgcg
    15901 gtgcaggcgg tcgctgcggc cgcgtccaag acctctacgg aggtgcaaac ggacccgtgg
    15961 atgtttcgcg tttcagcccc ccggcgcccg cgccgttcga ggaagtacgg cgccgccagc
    16021 gcgctactgc ccgaatatgc cctacatcct tccattgcgc ctacccccgg ctatcgtggc
    16081 tacacctacc gccccagaag acgagcaact acccgacgcc gaaccaccac tggaacccgc
    16141 cgccgccgtc gccgtcgcca gcccgtgctg gccccgattt ccgtgcgcag ggtggctcgc
    16201 gaaggaggca ggaccctggt gctgccaaca gcgcgctacc accccagcat cgtttaaaag
    16261 ccggtctttg tggttcttgc agatatggcc ctcacctgcc gcctccgttt cccggtgccg
    16321 ggattccgag gaagaatgca ccgtaggagg ggcatggccg gccacggcct gacgggcggc
    16381 atgcgtcgtg cgcaccaccg gcggcggcgc gcgtcgcacc gtcgcatgcg cggcggtatc
    16441 ctgcccctcc ttattccact gatcgccgcg gcgattggcg ccgtgcccgg aattgcatcc
    16501 gtggccttgc aggcgcagag acactgatta aaaacaagtt gcatgtggaa aaatcaaaat
    16561 aaaaagtctg gactctcacg ctcgcttggt cctgtaacta ttttgtagaa tggaagacat
    16621 caactttgcg tctctggccc cgcgacacgg ctcgcgcccg ttcatgggaa actggcaaga
    16681 tatcggcacc agcaatatga gcggtggcgc cttcagctgg ggctcgctgt ggagcggcat
    16741 taaaaatttc ggttccaccg ttaagaacta tggcagcaag gcctggaaca gcagcacagg
    16801 ccagatgctg agggataagt tgaaagagca aaatttccaa caaaaggtgg tagatggcct
    16861 ggcctctggc attagcgggg tggtggacct ggccaaccag gcagtgcaaa ataagattaa
    16921 cagtaagctt gatccccgcc ctcccgtaga ggagcctcca ccggccgtgg agacagtgtc
    16981 tccagagggg cgtggcgaaa agcgtccgcg ccccgacagg gaagaaactc tggtgacgca
    17041 aatagacgag cctccctcgt acgaggaggc actaaagcaa ggcctgccca ccacccgtcc
    17101 catcgcgccc atggctaccg gagtgctggg ccagcacaca cccgtaacgc tggacctgcc
    17161 tccccccgcc gacacccagc agaaacctgt gctgccaggc ccgaccgccg ttgttgtaac
    17221 ccgtcctagc cgcgcgtccc tgcgccgcgc cgccagcggt ccgcgatcgt tgcggcccgt
    17281 agccagtggc aactggcaaa gcacactgaa cagcatcgtg ggtctggggg tgcaatccct
    17341 gaagcgccga cgatgcttct gatagctaac gtgtcgtatg tgtgtcatgt atgcgtccat
    17401 gtcgccgcca gaggagctgc tgagccgccg cgcgcccgct ttccaagatg gctacccctt
    17461 cgatgatgcc gcagtggtct tacatgcaca tctcgggcca ggacgcctcg gagtacctga
    17521 gccccgggct ggtgcagttt gcccgcgcca ccgagacgta cttcagcctg aataacaagt
    17581 ttagaaaccc cacggtggcg cctacgcacg acgtgaccac agaccggtcc cagcgtttga
    17641 cgctgcggtt catccctgtg gaccgtgagg atactgcgta ctcgtacaag gcgcggttca
    17701 ccctagctgt gggtgataac cgtgtgctgg acatggcttc cacgtacttt gacatccgcg
    17761 gcgtgctgga caggggccct acttttaagc cctactctgg cactgcctac aacgccctgg
    17821 ctcccaaggg tgccccaaat ccttgcgaat gggatgaagc tgctactgct cttgaaataa
    17881 acctagaaga agaggacgat gacaacgaag acgaagtaga cgagcaagct gagcagcaaa
    17941 aaactcacgt atttgggcag gcgccttatt ctggtataaa tattacaaag gagggtattc
    18001 aaataggtgt cgaaggtcaa acacctaaat atgccgataa aacatttcaa cctgaacctc
    18061 aaataggaga atctcagtgg tacgaaacag aaattaatca tgcagctggg agagtcctaa
    18121 aaaagactac cccaatgaaa ccatgttacg gttcatatgc aaaacccaca aatgaaaatg
    18181 gagggcaagg cattcttgta aagcaacaaa atggaaagct agaaagtcaa gtggaaatgc
    18241 aatttttctc aactactgag gcagccgcag gcaatggtga taacttgact cctaaagtgg
    18301 tattgtacag tgaagatgta gatatagaaa ccccagacac tcatatttct tacatgccca
    18361 ctattaagga aggtaactca cgagaactaa tgggccaaca atctatgccc aacaggccta
    18421 attacattgc ttttagggac aattttattg gtctaatgta ttacaacagc acgggtaata
    18481 tgggtgttct ggcgggccaa gcatcgcagt tgaatgctgt tgtagatttg caagacagaa
    18541 acacagagct ttcataccag cttttgcttg attccattgg tgatagaacc aggtactttt
    18601 ctatgtggaa tcaggctgtt gacagctatg atccagatgt tagaattatt gaaaatcatg
    18661 gaactgaaga tgaacttcca aattactgct ttccactggg aggtgtgatt aatacagaga
    18721 ctcttaccaa ggtaaaacct aaaacaggtc aggaaaatgg atgggaaaaa gatgctacag
    18781 aattttcaga taaaaatgaa ataagagttg gaaataattt tgccatggaa atcaatctaa
    18841 atgccaacct gtggagaaat ttcctgtact ccaacatagc gctgtatttg cccgacaagc
    18901 taaagtacag tccttccaac gtaaaaattt ctgataaccc aaacacctac gactacatga
    18961 acaagcgagt ggtggctccc gggctagtgg actgctacat taaccttgga gcacgctggt
    19021 cccttgacta tatggacaac gtcaacccat ttaaccacca ccgcaatgct ggcctgcgct
    19081 accgctcaat gttgctgggc aatggtcgct atgtgccctt ccacatccag gtgcctcaga
    19141 agttctttgc cattaaaaac ctccttctcc tgccgggctc atacacctac gagtggaact
    19201 tcaggaagga tgttaacatg gttctgcaga gctccctagg aaatgaccta agggttgacg
    19261 gagccagcat taagtttgat agcatttgcc tttacgccac cttcttcccc atggcccaca
    19321 acaccgcctc cacgcttgag gccatgctta gaaacgacac caacgaccag tcctttaacg
    19381 actatctctc cgccgccaac atgctctacc ctatacccgc caacgctacc aacgtgccca
    19441 tatccatccc ctcccgcaac tgggcggctt tccgcggctg ggccttcacg cgccttaaga
    19501 ctaaggaaac cccatcactg ggctcgggct acgaccctta ttacacctac tctggctcta
    19561 taccctacct agatggaacc ttttacctca accacacctt taagaaggtg gccattacct
    19621 ttgactcttc tgtcagctgg cctggcaatg accgcctgct tacccccaac gagtttgaaa
    19681 ttaagcgctc agttgacggg gagggttaca acgttgccca gtgtaacatg accaaagact
    19741 ggttcctggt acaaatgcta gctaactata acattggcta ccagggcttc tatatcccag
    19801 agagctacaa ggaccgcatg tactccttct ttagaaactt ccagcccatg agccgtcagg
    19861 tggtggatga tactaaatac aaggactacc aacaggtggg catcctacac caacacaaca
    19921 actctggatt tgttggctac cttgccccca ccatgcgcga aggacaggcc taccctgcta
    19981 acttccccta tccgcttata ggcaagaccg cagttgacag cattacccag aaaaagtttc
    20041 tttgcgatcg caccctttgg cgcatcccat tctccagtaa ctttatgtcc atgggcgcac
    20101 tcacagacct gggccaaaac cttctctacg ccaactccgc ccacgcgcta gacatgactt
    20161 ttgaggtgga tcccatggac gagcccaccc ttctttatgt tttgtttgaa gtctttgacg
    20221 tggtccgtgt gcaccagccg caccgcggcg tcatcgaaac cgtgtacctg cgcacgccct
    20281 tctcggccgg caacgccaca acataaagaa gcaagcaaca tcaacaacag ctgccgccat
    20341 gggctccagt gagcaggaac tgaaagccat tgtcaaagat cttggttgtg ggccatattt
    20401 tttgggcacc tatgacaagc gctttccagg ctttgtttct ccacacaagc tcgcctgcgc
    20461 catagtcaat acggccggtc gcgagactgg gggcgtacac tggatggcct ttgcctggaa
    20521 cccgcactca aaaacatgct acctctttga gccctttggc ttttctgacc agcgactcaa
    20581 gcaggtttac cagtttgagt acgagtcact cctgcgccgt agcgccattg cttcttcccc
    20641 cgaccgctgt ataacgctgg aaaagtccac ccaaagcgta caggggccca actcggccgc
    20701 ctgtggacta ttctgctgca tgtttctcca cgcctttgcc aactggcccc aaactcccat
    20761 ggatcacaac cccaccatga accttattac cggggtaccc aactccatgc tcaacagtcc
    20821 ccaggtacag cccaccctgc gtcgcaacca ggaacagctc tacagcttcc tggagcgcca
    20881 ctcgccctac ttccgcagcc acagtgcgca gattaggagc gccacttctt tttgtcactt
    20941 gaaaaacatg taaaaataat gtactagaga cactttcaat aaaggcaaat gcttttattt
    21001 gtacactctc gggtgattat ttacccccac ccttgccgtc tgcgccgttt aaaaatcaaa
    21061 ggggttctgc cgcgcatcgc tatgcgccac tggcagggac acgttgcgat actggtgttt
    21121 agtgctccac ttaaactcag gcacaaccat ccgcggcagc tcggtgaagt tttcactcca
    21181 caggctgcgc accatcacca acgcgtttag caggtcgggc gccgatatct tgaagtcgca
    21241 gttggggcct ccgccctgcg cgcgcgagtt gcgatacaca gggttgcagc actggaacac
    21301 tatcagcgcc gggtggtgca cgctggccag cacgctcttg tcggagatca gatccgcgtc
    21361 caggtcctcc gcgttgctca gggcgaacgg agtcaacttt ggtagctgcc ttcccaaaaa
    21421 gggcgcgtgc ccaggctttg agttgcactc gcaccgtagt ggcatcaaaa ggtgaccgtg
    21481 cccggtctgg gcgttaggat acagcgcctg cataaaagcc ttgatctgct taaaagccac
    21541 ctgagccttt gcgccttcag agaagaacat gccgcaagac ttgccggaaa actgattggc
    21601 cggacaggcc gcgtcgtgca cgcagcacct tgcgtcggtg ttggagatct gcaccacatt
    21661 tcggccccac cggttcttca cgatcttggc cttgctagac tgctccttca gcgcgcgctg
    21721 cccgttttcg ctcgtcacat ccatttcaat cacgtgctcc ttatttatca taatgcttcc
    21781 gtgtagacac ttaagctcgc cttcgatctc agcgcagcgg tgcagccaca acgcgcagcc
    21841 cgtgggctcg tgatgcttgt aggtcacctc tgcaaacgac tgcaggtacg cctgcaggaa
    21901 tcgccccatc atcgtcacaa aggtcttgtt gctggtgaag gtcagctgca acccgcggtg
    21961 ctcctcgttc agccaggtct tgcatacggc cgccagagct tccacttggt caggcagtag
    22021 tttgaagttc gcctttagat cgttatccac gtggtacttg tccatcagcg cgcgcgcagc
    22081 ctccatgccc ttctcccacg cagacacgat cggcacactc agcgggttca tcaccgtaat
    22141 ttcactttcc gcttcgctgg gctcttcctc ttcctcttgc gtccgcatac cacgcgccac
    22201 tgggtcgtct tcattcagcc gccgcactgt gcgcttacct cctttgccat gcttgattag
    22261 caccggtggg ttgctgaaac ccaccatttg tagcgccaca tcttctcttt cttcctcgct
    22321 gtccacgatt acctctggtg atggcgggcg ctcgggcttg ggagaagggc gcttcttttt
    22381 cttcttgggc gcaatggcca aatccgccgc cgaggtcgat ggccgcgggc tgggtgtgcg
    22441 cggcaccagc gcgtcttgtg atgagtcttc ctcgtcctcg gactcgatac gccgcctcat
    22501 ccgctttttt gggggcgccc ggggaggcgg cggcgacggg gacggggacg acacgtcctc
    22561 catggttggg ggacgtcgcg ccgcaccgcg tccgcgctcg ggggtggttt cgcgctgctc
    22621 ctcttcccga ctggccattt ccttctccta taggcagaaa aagatcatgg agtcagtcga
    22681 gaagaaggac agcctaaccg ccccctctga gttcgccacc accgcctcca ccgatgccgc
    22741 caacgcgcct accaccttcc ccgtcgaggc acccccgctt gaggaggagg aagtgattat
    22801 cgagcaggac ccaggttttg taagcgaaga cgacgaggac cgctcagtac caacagagga
    22861 taaaaagcaa gaccaggaca acgcagaggc aaacgaggaa caagtcgggc ggggggacga
    22921 aaggcatggc gactacctag atgtgggaga cgacgtgctg ttgaagcatc tgcagcgcca
    22981 gtgcgccatt atctgcgacg cgttgcaaga gcgcagcgat gtgcccctcg ccatagcgga
    23041 tgtcagcctt gcctacgaac gccacctatt ctcaccgcgc gtacccccca aacgccaaga
    23101 aaacggcaca tgcgagccca acccgcgcct caacttctac cccgtatttg ccgtgccaga
    23161 ggtgcttgcc acctatcaca tctttttcca aaactgcaag atacccctat cctgccgtgc
    23221 caaccgcagc cgagcggaca agcagctggc cttgcggcag ggcgctgtca tacctgatat
    23281 cgcctcgctc aacgaagtgc caaaaatctt tgagggtctt ggacgcgacg agaagcgcgc
    23341 ggcaaacgct ctgcaacagg aaaacagcga aaatgaaagt cactctggag tgttggtgga
    23401 actcgagggt gacaacgcgc gcctagccgt actaaaacgc agcatcgagg tcacccactt
    23461 tgcctacccg gcacttaacc taccccccaa ggtcatgagc acagtcatga gtgagctgat
    23521 cgtgcgccgt gcgcagcccc tggagaggga tgcaaatttg caagaacaaa cagaggaggg
    23581 cctacccgca gttggcgacg agcagctagc gcgctggctt caaacgcgcg agcctgccga
    23641 cttggaggag cgacgcaaac taatgatggc cgcagtgctc gttaccgtgg agcttgagtg
    23701 catgcagcgg ttctttgctg acccggagat gcagcgcaag ctagaggaaa cattgcacta
    23761 cacctttcga cagggctacg tacgccaggc ctgcaagatc tccaacgtgg agctctgcaa
    23821 cctggtctcc taccttggaa ttttgcacga aaaccgcctt gggcaaaacg tgcttcattc
    23881 cacgctcaag ggcgaggcgc gccgcgacta cgtccgcgac tgcgtttact tatttctatg
    23941 ctacacctgg cagacggcca tgggcgtttg gcagcagtgc ttggaggagt gcaacctcaa
    24001 ggagctgcag aaactgctaa agcaaaactt gaaggaccta tggacggcct tcaacgagcg
    24061 ctccgtggcc gcgcacctgg cggacatcat tttccccgaa cgcctgctta aaaccctgca
    24121 acagggtctg ccagacttca ccagtcaaag catgttgcag aactttagga actttatcct
    24181 agagcgctca ggaatcttgc ccgccacctg ctgtgcactt cctagcgact ttgtgcccat
    24241 taagtaccgc gaatgccctc cgccgctttg gggccactgc taccttctgc agctagccaa
    24301 ctaccttgcc taccactctg acataatgga agacgtgagc ggtgacggtc tactggagtg
    24361 tcactgtcgc tgcaacctat gcaccccgca ccgctccctg gtttgcaatt cgcagctgct
    24421 taacgaaagt caaattatcg gtacctttga gctgcagggt ccctcgcctg acgaaaagtc
    24481 cgcggctccg gggttgaaac tcactccggg gctgtggacg tcggcttacc ttcgcaaatt
    24541 tgtacctgag gactaccacg cccacgagat taggttctac gaagaccaat cccgcccgcc
    24601 taatgcggag cttaccgcct gcgtcattac ccagggccac attcttggcc aattgcaagc
    24661 catcaacaaa gcccgccaag agtttctgct acgaaaggga cggggggttt acttggaccc
    24721 ccagtccggc gaggagctca acccaatccc cccgccgccg cagccctatc agcagcagcc
    24781 gcgggccctt gcttcccagg atggcaccca aaaagaagct gcagctgccg ccgccaccca
    24841 cggacgagga ggaatactgg gacagtcagg cagaggaggt tttggacgag gaggaggagg
    24901 acatgatgga agactgggag agcctagacg aggaagcttc cgaggtcgaa gaggtgtcag
    24961 acgaaacacc gtcaccctcg gtcgcattcc cctcgccggc gccccagaaa tcggcaaccg
    25021 gttccagcat ggctacaacc tccgctcctc aggcgccgcc ggcactgccc gttcgccgac
    25081 ccaaccgtag atgggacacc actggaacca gggccggtaa gtccaagcag ccgccgccgt
    25141 tagcccaaga gcaacaacag cgccaaggct accgctcatg gcgcgggcac aagaacgcca
    25201 tagttgcttg cttgcaagac tgtgggggca acatctcctt cgcccgccgc tttcttctct
    25261 accatcacgg cgtggccttc ccccgtaaca tcctgcatta ctaccgtcat ctctacagcc
    25321 catactgcac cggcggcagc ggcagcaaca gcagcggcca cacagaagca aaggcgaccg
    25381 gatagcaaga ctctgacaaa gcccaagaaa tccacagcgg cggcagcagc aggaggagga
    25441 gcgctgcgtc tggcgcccaa cgaacccgta tcgacccgcg agcttagaaa caggattttt
    25501 cccactctgt atgctatatt tcaacagagc aggggccaag aacaagagct gaaaataaaa
    25561 aacaggtctc tgcgatccct cacccgcagc tgcctgtatc acaaaagcga agatcagctt
    25621 cggcgcacgc tggaagacgc ggaggctctc ttcagtaaat actgcgcgct gactcttaag
    25681 gactagtttc gcgccctttc tcaaatttaa gcgcgaaaac tacgtcatct ccagcggcca
    25741 cacccggcgc cagcacctgt tgtcagcgcc attatgagca aggaaattcc cacgccctac
    25801 atgtggagtt accagccaca aatgggactt gcggctggag ctgcccaaga ctactcaacc
    25861 cgaataaact acatgagcgc gggaccccac atgatatccc gggtcaacgg aatacgcgcc
    25921 caccgaaacc gaattctcct ggaacaggcg gctattacca ccacacctcg taataacctt
    25981 aatccccgta gttggcccgc tgccctggtg taccaggaaa gtcccgctcc caccactgtg
    26041 gtacttccca gagacgccca ggccgaagtt cagatgacta actcaggggc gcagcttgcg
    26101 ggcggctttc gtcacagggt gcggtcgccc gggcagggta taactcacct gacaatcaga
    26161 gggcgaggta ttcagctcaa cgacgagtcg gtgagctcct cgcttggtct ccgtccggac
    26221 gggacatttc agatcggcgg cgccggccgc tcttcattca cgcctcgtca ggcaatccta
    26281 actctgcaga cctcgtcctc tgagccgcgc tctggaggca ttggaactct gcaatttatt
    26341 gaggagtttg tgccatcggt ctactttaac cccttctcgg gacctcccgg ccactatccg
    26401 gatcaattta ttcctaactt tgacgcggta aaggactcgg cggacggcta cgactgaatg
    26461 ttataagttc ctgtccatcc gcacccacta tcttcatgtt gttgcagatg aagcgcgcaa
    26521 gaccgtctga agataccttc aaccccgtgt atccatatga cacggaaacc ggtcctccaa
    26581 ctgtgccttt tcttactcct ccctttgtat cccccaatgg gtttcaagag agtccccctg
    26641 gggtactctc tttgcgccta tccgaacctc tagttacctc caatggcatg cttgcgctca
    26701 aaatgggcaa cggcctctct ctggacgagg ccggcaacct tacctcccaa aatgtaacca
    26761 ctgtgagccc acctctcaaa aaaaccaagt caaacataaa cctggaaata tctgcacccc
    26821 tcacagttac ctcagaagcc ctaactgtgg ctgccgccgc acctctaatg gtcgcgggca
    26881 acacactcac catgcaatca caggccccgc taaccgtgca cgactccaaa cttagcattg
    26941 ccacccaagg acccctcaca gtgtcagaag gaaagctagc cctgcaaaca tcaggccccc
    27001 tcaccaccac cgatagcagt acccttacta tcactgcctc accccctcta actactgcca
    27061 ctggtagctt gggcattgac ttgaaagagc ccatttatac acaaaatgga aaactaggac
    27121 taaagtacgg ggctcctttg catgtaacag acgacctaaa cactttgacc gtagcaactg
    27181 gtccaggtgt gactattaat aatacttcct tgcaaactaa agttactgga gccttgggtt
    27241 ttgattcaca aggcaatatg caacttaatg tagcaggagg actaaggatt gattctcaaa
    27301 acagacgcct tatacttgat gttagttatc cgtttgatgc tcaaaaccaa ctaaatctaa
    27361 gactaggaca gggccctctt tttataaact cagcccacaa cttggatatt aactacaaca
    27421 aaggccttta cttgtttaca gcttcaaaca attccaaaaa gcttgaggtt aacctaagca
    27481 ctgccaaggg gttgatgttt gacgctacag ccatagccat taatgcagga gatgggcttg
    27541 aatttggttc acctaatgca ccaaacacaa atcccctcaa aacaaaaatt ggccatggcc
    27601 tagaatttga ttcaaacaag gctatggttc ctaaactagg aactggcctt agttttgaca
    27661 gcacaggtgc cattacagta ggaaacaaaa ataatgataa gctaactttg tggaccacac
    27721 cagctccatc tcctaactgt agactaaatg cagagaaaga tgctaaactc actttggtct
    27781 taacaaaatg tggcagtcaa atacttgcta cagtttcagt tttggctgtt aaaggcagtt
    27841 tggctccaat atctggaaca gttcaaagtg ctcatcttat tataagattt gacgaaaatg
    27901 gagtgctact aaacaattcc ttcctggacc cagaatattg gaactttaga aatggagatc
    27961 ttactgaagg cacagcctat acaaacgctg ttggatttat gcctaaccta tcagcttatc
    28021 caaaatctca cggtaaaact gccaaaagta acattgtcag tcaagtttac ttaaacggag
    28081 acaaaactaa acctgtaaca ctaaccatta cactaaacgg tacacaggaa acaggagaca
    28141 caactccaag tgcatactct atgtcatttt catgggactg gtctggccac aactacatta
    28201 atgaaatatt tgccacatcc tcttacactt tttcatacat tgcccaagaa taaagaatcg
    28261 tttgtgttat gtttcaacgt gtttattttt caattgcaga aaatttcaag tcatttttca
    28321 ttcagtagta tagccccacc accacatagc ttatacagat caccgtacct taatcaaact
    28381 cacagaaccc tagtattcaa cctgccacct ccctcccaac acacagagta cacagtcctt
    28441 tctccccggc tggccttaaa aagcatcata tcatgggtaa cagacatatt cttaggtgtt
    28501 atattccaca cggtttcctg tcgagccaaa cgctcatcag tgatattaat aaactccccg
    28561 ggcagctcac ttaagttcat gtcgctgtcc agctgctgag ccacaggctg ctgtccaact
    28621 tgcggttgct taacgggcgg cgaaggagaa gtccacgcct acatgggggt agagtcataa
    28681 tcgtgcatca ggatagggcg gtggtgctgc agcagcgcgc gaataaactg ctgccgccgc
    28741 cgctccgtcc tgcaggaata caacatggca gtggtctcct cagcgatgat tcgcaccgcc
    28801 cgcagcataa ggcgccttgt cctccgggca cagcagcgca ccctgatctc acttaaatca
    28861 gcacagtaac tgcagcacag caccacaata ttgttcaaaa tcccacagtg caaggcgctg
    28921 tatccaaagc tcatggcggg gaccacagaa cccacgtggc catcatacca caagcgcagg
    28981 tagattaagt ggcgacccct cataaacacg ctggacataa acattacctc ttttggcatg
    29041 ttgtaattca ccacctcccg gtaccatata aacctctgat taaacatggc gccatccacc
    29101 accatcctaa accagctggc caaaacctgc ccgccggcta tacactgcag ggaaccggga
    29161 ctggaacaat gacagtggag agcccaggac tcgtaaccat ggatcatcat gctcgtcatg
    29221 atatcaatgt tggcacaaca caggcacacg tgcatacact tcctcaggat tacaagctcc
    29281 tcccgcgtta gaaccatatc ccagggaaca acccattcct gaatcagcgt aaatcccaca
    29341 ctgcagggaa gacctcgcac gtaactcacg ttgtgcattg tcaaagtgtt acattcgggc
    29401 agcagcggat gatcctccag tatggtagcg cgggtttctg tctcaaaagg aggtagacga
    29461 tccctactgt acggagtgcg ccgagacaac cgagatcgtg ttggtcgtag tgtcatgcca
    29521 aatggaacgc cggacgtagt catatttcct gaagcaaaac caggtgcggg cgtgacaaac
    29581 agatctgcgt ctccggtctc gccgcttaga tcgctctgtg tagtagttgt agtatatcca
    29641 ctctctcaaa gcatccaggc gccccctggc ttcgggttct atgtaaactc cttcatgcgc
    29701 cgctgccctg ataacatcca ccaccgcaga ataagccaca cccagccaac ctacacattc
    29761 gttctgcgag tcacacacgg gaggagcggg aagagctgga agaaccatgt tttttttttt
    29821 attccaaaag attatccaaa acctcaaaat gaagatctat taagtgaacg cgctcccctc
    29881 cggtggcgtg gtcaaactct acagccaaag aacagataat ggcatttgta agatgttgca
    29941 caatggcttc caaaaggcaa acggccctca cgtccaagtg gacgtaaagg ctaaaccctt
    30001 cagggtgaat ctcctctata aacattccag caccttcaac catgcccaaa taattctcat
    30061 ctcgccacct tctcaatata tctctaagca aatcccgaat attaagtccg gccattgtaa
    30121 aaatctgctc cagagcgccc tccaccttca gcctcaagca gcgaatcatg attgcaaaaa
    30181 ttcaggttcc tcacagacct gtataagatt caaaagcgga acattaacaa aaataccgcg
    30241 atcccgtagg tcccttcgca gggccagctg aacataatcg tgcaggtctg cacggaccag
    30301 cgcggccact tccccgccag gaaccatgac aaaagaaccc acactgatta tgacacgcat
    30361 actcggagct atgctaacca gcgtagcccc gatgtaagct tgttgcatgg gcggcgatat
    30421 aaaatgcaag gtgctgctca aaaaatcagg caaagcctcg cgcaaaaaag aaagcacatc
    30481 gtagtcatgc tcatgcagat aaaggcaggt aagctccgga accaccacag aaaaagacac
    30541 catttttctc tcaaacatgt ctgcgggttt ctgcataaac acaaaataaa ataacaaaaa
    30601 aacatttaaa cattagaagc ctgtcttaca acaggaaaaa caacccttat aagcataaga
    30661 cggactacgg ccatgccggc gtgaccgtaa aaaaactggt caccgtgatt aaaaagcacc
    30721 accgacagct cctcggtcat gtccggagtc ataatgtaag actcggtaaa cacatcaggt
    30781 tgattcacat cggtcagtgc taaaaagcga ccgaaatagc ccgggggaat acatacccgc
    30841 aggcgtagag acaacattac agcccccata ggaggtataa caaaattaat aggagagaaa
    30901 aacacataaa cacctgaaaa accctcctgc ctaggcaaaa tagcaccctc ccgctccaga
    30961 acaacataca gcgcttccac agcggcagcc ataacagtca gccttaccag taaaaaagaa
    31021 aacctattaa aaaaacacca ctcgacacgg caccagctca atcagtcaca gtgtaaaaaa
    31081 gggccaagtg cagagcgagt atatatagga ctaaaaaatg acgtaacggt taaagtccac
    31141 aaaaaacacc cagaaaaccg cacgcgaacc tacgcccaga aacgaaagcc aaaaaaccca
    31201 caacttcctc aaatcgtcac ttccgttttc ccacgttacg tcacttccca ttttaagaaa
    31261 actacaattc ccaacacata caagttactc cgccctaaaa cctacgtcac ccgccccgtt
    31321 cccacgcccc gcgccacgtc acaaactcca ccccctcatt atcatattgg cttcaatcca
    31381 aaataaggta tattattgat gatgttacat cgttaattaa cgatttcgaa cccggggtac
    31441 cgaattcctc gagtctagag gagcatgcga cgtcgcaatt cgccctatag tgagtcgtat
    31501 tacaattcac tggccgtcgt tttacaacgt cgtgactggg aaaaccctgg cgttacccaa
    31561 cttaatcgcc ttgcagcaca tccccctttc gccagctggc gtaatagcga agaggcccgc
    31621 accgatcgcc cttcccaaca gttgcgcagc ctgaatggcg aatggaaatt gtaagcgtta
    31681 atattttgtt aaaattcgcg ttaaattttt gttaaatcag ctcatttttt aaccaatagg
    31741 ccgaaatcgg caaaatccct tataaatcaa aagaatagac cgagataggg ttgagtgttg
    31801 ttccagtttg gaacaagagt ccactattaa agaacgtgga ctccaacgtc aaagggcgaa
    31861 aaaccgtcta tcagggcgat ggcccactac gtgaaccatc accctaatca agttttttgg
    31921 ggtcgaggtg ccgtaaagca ctaaatcgga accctaaagg gagcccccga tttagagctt
    31981 gacggggaaa gccggcgaac gtggcgagaa aggaagggaa gaaagcgaaa ggagcgggcg
    32041 ctagggcgct ggcaagtgta gcggtcacgc tgcgcgtaac caccacaccc gccgcgctta
    32101 atgcgccgct acagggcgcg tcctgatgcg gtattttctc cttacgcatc tgtgcggtat
    32161 ttcacaccgc atacaggtgg cacttttcgg ggaaatgtgc gcggaacccc tatttgttta
    32221 tttttctaaa tacattcaaa tatgtatccg ctcatgagac aataaccctg ataaatgctt
    32281 caataatatt gaaaaaggaa gagtatgagt attcaacatt tccgtgtcgc ccttattccc
    32341 ttttttgcgg cattttgcct tcctgttttt gctcacccag aaacgctggt gaaagtaaaa
    32401 gatgctgaag atcagttggg tgcacgagtg ggttacatcg aactggatct caacagcggt
    32461 aagatccttg agagttttcg ccccgaagaa cgttttccaa tgatgagcac ttttaaagtt
    32521 ctgctatgtg gcgcggtatt atcccgtatt gacgccgggc aagagcaact cggtcgccgc
    32581 atacactatt ctcagaatga cttggttgag tactcaccag tcacagaaaa gcatcttacg
    32641 gatggcatga cagtaagaga attatgcagt gctgccataa ccatgagtga taacactgcg
    32701 gccaacttac ttctgacaac gatcggagga ccgaaggagc taaccgcttt tttgcacaac
    32761 atgggggatc atgtaactcg ccttgatcgt tgggaaccgg agctgaatga agccatacca
    32821 aacgacgagc gtgacaccac gatgcctgta gcaatggcaa caacgttgcg caaactatta
    32881 actggcgaac tacttactct agcttcccgg caacaattaa tagactggat ggaggcggat
    32941 aaagttgcag gaccacttct gcgctcggcc cttccggctg gctggtttat tgctgataaa
    33001 tctggagccg gtgagcgtgg gtctcgcggt atcattgcag cactggggcc agatggtaag
    33061 ccctcccgta tcgtagttat ctacacgacg gggagtcagg caactatgga tgaacgaaat
    33121 agacagatcg ctgagatagg tgcctcactg attaagcatt ggtaactgtc agaccaagtt
    33181 tactcatata tactttagat tgatttaaaa cttcattttt aatttaaaag gatctaggtg
    33241 aagatccttt ttgataatct catgaccaaa atcccttaac gtgagttttc gttccactga
    33301 gcgtcagacc ccgtagaaaa gatcaaagga tcttcttgag atcctttttt tctgcgcgta
    33361 atctgctgct tgcaaacaaa aaaaccaccg ctaccagcgg tggtttgttt gccggatcaa
    33421 gagctaccaa ctctttttcc gaaggtaact ggcttcagca gagcgcagat accaaatact
    33481 gttcttctag tgtagccgta gttaggccac cacttcaaga actctgtagc accgcctaca
    33541 tacctcgctc tgctaatcct gttaccagtg gctgctgcca gtggcgataa gtcgtgtctt
    33601 accgggttgg actcaagacg atagttaccg gataaggcgc agcggtcggg ctgaacgggg
    33661 ggttcgtgca cacagcccag cttggagcga acgacctaca ccgaactgag atacctacag
    33721 cgtgagctat gagaaagcgc cacgcttccc gaagggagaa aggcggacag gtatccggta
    33781 agcggcaggg tcggaacagg agagcgcacg agggagcttc cagggggaaa cgcctggtat
    33841 ctttatagtc ctgtcgggtt tcgccacctc tgacttgagc gtcgattttt gtgatgctcg
    33901 tcaggggggc ggagcctatg gaaaaacgcc agcaacgcgg cctttttacg gttcctggcc
    33961 ttttgctggc cttttgctca catgttcttt cctgcgttat cccctgattc tgtggataac
    34021 cgtattaccg cctttgagtg agctgatacc gctcgccgca gccgaacgac cgagcgcagc
    34081 gagtcagtga gcgaggaagc ggaagagcgc ccaatacgca aaccgcctct ccccgcgcgt
    34141 tggccgattc attaatgcag ctggcacgac aggtttcccg actggaaagc gggcagtgag
    34201 cgcaacgcaa ttaatgtgag ttagctcact cattaggcac cccaggcttt acactttatg
    34261 cttccggctc gtatgttgtg tggaattgtg agcggataac aatttcacac aggaaacagc
    34321 tatgaccatg attacgccaa gctatttagg tgacactata gaatactcaa gctagttaat
    34381 taacgttaat taacatcatc aataatatac cttattttgg attgaagcca atatgataat
    34441 gagggggtgg agtttgtgac gtggcgcggg gcgtgggaac ggggcgggtg acgtagtagt
    34501 gtggcggaag tgtgatgttg caagtgtggc ggaacacatg taagcgacgg atgtggcaaa
    34561 agtgacgttt ttggtgtgcg ccggtgtaca caggaagtga caattttcgc gcggttttag
    34621 gcggatgttg tagtaaattt gggcgtaacc gagtaagatt tggccatttt cgcgggaaaa
    34681 ctgaataaga ggaagtgaaa tctgaataat tttgtgttac tcatagcgcg taatctctag
    34741 catcgtaact ataacggtcc taaggtagcg aaagctcaga tctcccgatc ccctatggtg
    34801 cactctcagt acaatctgct ctgatgccgc atagttaagc cagtatctgc tccctgcttg
    34861 tgtgttggag gtcgctgagt agtgcgcgag caaaatttaa gctacaacaa ggcaaggctt
    34921 gaccgacaat tgcatgaaga atctgcttag ggttaggcgt tttgcgctgc ttcgcgatgt
    34981 acgggccaga tatacgcgtt
//
