LOCUS       sequence-46452-e         840 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 840)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 840)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-ACVR2B
FEATURES             Location/Qualifiers
     source          1..840
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    18..117
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 acccccggag ctggatggca ataatgattt tattttgact gatagtgacc tgttcgttgc
       61 aacaaattga taagcaatgc tttcttataa tgccaacttt gtacaagaaa gttggcaaga
      121 tgcttgactc tttagggggc aggtccacat tggtgacaga ggtcaccagg gaaacgagac
      181 agtccgaggt agtgccattg accgacctcc gaatcaggga cacccgctcc tccacacagc
      241 ccgcggacaa gcgagcctct gcatcatggt cccagcactc ctcgatggtc acacaaagct
      301 gggccaggcc cgggtgtttc aaccagtgat ctttaatggt gggcctcatc ttcttgtgca
      361 ccaccacctc ctgcagctcc tccaacgaag ggtgctggcc aatctcttcc tcaaagggca
      421 gcatgtactc atccacgggt ccgtctgcag ccttgcagcg agacacaagc tcccacagca
      481 ccaaccccat ggcatacatg tcaatgcgca ggaaggcatc tctctggaag ttgatggctc
      541 cctcgagcac ctcaggagcc atgtaccgtc tcgtgcctac ctgtccgtgg gtgtcccctg
      601 gaggtttccc tggctcaaat cgaacagcca agccaaagtc agccagcacg gctgtgaggt
      661 cgctcttcag caatacattc ttacttttaa agtccctgtg ggcaatagac ggcttgtggc
      721 cctcgccacg gcaccagggc acatcctcat gcaggtatga gaggcctcgt gacatcgtct
      781 ctgctacatg acacagttcg ttccatgtga tgatgttccc cttgaggtaa tccgtgagga
//
