LOCUS       sequence-46539-e         769 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 769)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 769)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PRKG1
FEATURES             Location/Qualifiers
     source          1..769
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    12..111
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 acagctggat ggcaataatg attttatttt gactgatagt gacctgttcg ttgcaacaaa
       61 ttgataagca atgctttctt ataatgccaa ctttgtacaa gaaagttggc aagaagtcta
      121 tatcccatcc tgagttgtca tcaggtggtg gttcatcgtt gtcctcaggg aaactgtcaa
      181 aattacttgt gtctgtgggt gatgcaacac ttggtattat aggaggtgtc aaggtacctt
      241 ttcttaagcc ttcccagtta aagccctcaa accatttgtg cttttgaatg tcttttactc
      301 catttttcaa attccctaat ctttctgatg gattgtccct gcatagtttt ttaattaaat
      361 tagcagcatt tttggcaatc ttctttggaa attctatcat gtcaatcccc ctcaatatga
      421 tgttataggt tttcatagga tctgggcctg agaaaggtgg gctgccagtc aggagttcat
      481 acattaggat tcccagtgac cagtagtcgg ctgaaatgtc atggcctttg ttcaggatga
      541 tctctggggc tacatactct ggagtcccac aaaaagtcca tgttttcttt ccaaatccta
      601 ttttctttgc aaagccaaaa tcaaccagtt tggcataacc tcggtgatct aggatgagat
      661 tttctggctt gaggtccctg taaatgattc ctttggaatg cagataggca aaagcttcta
      721 ccacacatgc tgtgtaaaat ctggttgtag aatcttcaaa cgaacctct
//
