LOCUS       sequence-46876-e         709 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 709)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 709)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-DGKB
FEATURES             Location/Qualifiers
     source          1..709
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    17..116
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 gatttcagct gggatggcaa taatgatttt attttgactg atagtgacct gttcgttgca
       61 acaaattgat aagcaatgct ttcttataat gccaactttg tacaagaaag ttggcaattc
      121 cttgcttcgg tttcttgtcc ttttgacgag ggagcagaat aaaccggttt ttggaggcgg
      181 gcccatcagc attggggctt ggttcttgtg tgtaattttt attgtgcatg gggtctgcat
      241 ccatggctcc ccatcaattt gcattggcag agacttgctc gtcctgatga ccacgcagga
      301 gcactgagcc agccgccggc cagcactttt caggcctgtg tatatttgcc ccatctccat
      361 ggctccttcc aagccgacca cctccagcag ctggtcactg agatcttgac ttgcaaactt
      421 caactctttg gcatctgtga cggtggtcct tttgtcagac ccttttttct ctattcgtcg
      481 atggcttcgt cttttcttag actctcccca aagattggat cctccatgca tgcttggtat
      541 attcaaaata gcaattcctt ccagagagat gtttattaaa tctatctgta ctccatcaca
      601 ttctatttct acagattcat gtagcttctt gcaggtggct gagaaagttt cagatgtgcc
      661 aaactcaaaa taccaaaatt tgttcttcat tctactgttg aatttctct
//
