LOCUS       sequence-46919-e         839 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 839)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 839)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-NEK4
FEATURES             Location/Qualifiers
     source          1..839
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    18..117
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 gcggggatag ctggatggca ataatgattt tattttgact gatagtgacc tgttcgttgc
       61 aacaaattga taagcaatgc tttcttataa tgccaacttt gtacaagaaa gttggcaaaa
      121 aaattctata acataagcat cttgatacag ttaatgagac actcacctct ctatcaaatt
      181 catcctcctc ctccaaaaga tcatacacct gctctaaaag ctgaactccc aggccacgaa
      241 ttacatcagt tctcaagact tcaactagtc tcctgatctt ttcagaacct ggcataatag
      301 ctgaaggtag ctctttaaaa tggatttcct ctgcctcttc tgcaaccttc ccatgaagta
      361 tcagtgtgtc ccgatatttc cgatgaagtt tgaattctga cactgggttt gctaccggga
      421 catcttcaca gctctcttta gaatccagtt tcagggtctg agtcatcaat tgtaccaagg
      481 cattaatttc atttgtctga cctttccctt ccccgtaatc cccatctgac ttatcagttg
      541 aacttgtaga agaacttaac tcatcctcag acagacaatg aatctgtttc ctttcctgaa
      601 gaggacattt cttcctgtga ctgctttagt cgcctcctct ctctggctga taatggtcga
      661 tcctttgatg atgacatctc actgctcctt gaactgctca cagacccagt gaccactcta
      721 cgttggtttt cagcctcttt ttgtgttgat gtgacatcca ctttcccaac aatgggatga
      781 gaaggcaaaa atcgaggagg cgactcttgg aaagcaaaga gatctctgcg gacctgtct
//
