LOCUS       sequence-73921-e         854 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expresses HA-tagged ER Y537S mutant in mammalian cells.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 854)
  AUTHORS   Toy W, Shen Y, Won H, Green B, Sakr RA, Will M, Li Z, Gala K, 
            Fanning S, King TA, Hudis C, Chen D, Taran T, Hortobagyi G, Greene 
            G, Berger M, Baselga J, Chandarlapaty S
  TITLE     ESR1 ligand-binding domain mutations in hormone-resistant breast 
            cancer.
  JOURNAL   Nat Genet. 2013 Dec;45(12):1439-45. doi: 10.1038/ng.2822. Epub 2013 
            Nov 3.
  PUBMED    24185512
REFERENCE   2  (bases 1 to 854)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10.1038/ng.2822"; 
            journalName: "Nat Genet"; date: "2013-12"; volume: "45"; issue: 
            "12"; pages: "1439-45"
COMMENT     Sequence Label: pcDNA-HA-ER Y537S
FEATURES             Location/Qualifiers
     source          1..854
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 acagcctggc cttgtccctg acggccgacc agatggtcag tgccttgttg gatgctgagc
       61 cccccatact ctattccgag tatgatccta ccagaccctt cagtgaagct tcgatgatgg
      121 gcttactgac caacctggca gacagggagc tggttcacat gatcaactgg gcgaagaggg
      181 tgccaggctt tgtggatttg accctccatg atcaggtcca ccttctagaa tgtgcctggc
      241 tagagatcct gatgattggt ctcgtctggc gctccatgga gcacccaggg aagctactgt
      301 ttgctcctaa cttgctcttg gacaggaacc agggaaaatg tgtagagggc atggtggaga
      361 tcttcgacat gctgctggct acatcatctc ggttccgcat gatgaatctg cagggagagg
      421 agtttgtgtg cctcaaatct attattttgc ttaattctgg agtgtacaca tttctgtcca
      481 gcaccctgaa gtctctggaa gagaaggacc atatccaccg agtcctggac aagatcacag
      541 acactttgat ccacctgatg gccaaggcag gcctgaccct gcagcagcag caccagcggc
      601 tggcccagct cctcctcatc ctctcccaca tcaggcacat gagtaacaaa ggcatggagc
      661 atctgtacag catgaagtgc aagaacgtgg tgcccctcag tgacctgctg ctggagatgc
      721 tggacgccca ccgcctacat gcgcccacta gccgtggagg ggcatccgtg gaggagacgg
      781 accaaagcca cttggccact gcgggctcta cttcatcgca ttccttgcaa aagtattaca
      841 tcacggggga ggca
//
