LOCUS       sequence-93997-e         878 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of constitutively active human IKK-2.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 878)
  AUTHORS   Mercurio F, Zhu H, Murray BW, Shevchenko A, Bennett BL, Li J, Young 
            DB, Barbosa M, Mann M, Manning A, Rao A
  TITLE     IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for 
            NF-kappaB activation.
  JOURNAL   Science. 1997 Oct 31. 278(5339):860-6.
  PUBMED    9346484
REFERENCE   2  (bases 1 to 878)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Science. 
            1997 Oct 31. 278(5339):860-6."
COMMENT     Sequence Label: IKK-2 S177E S181E
FEATURES             Location/Qualifiers
     source          1..878
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             31..54
                     /codon_start=1
                     /product="FLAG(R) epitope tag, followed by an enterokinase 
                     cleavage site"
                     /label=FLAG
                     /translation="DYKDDDDK"
ORIGIN
        1 ttagtgaacc gtcagaattg atctaccatg gactacaaag acgatgacga caagcttgcg
       61 gccgcaatga gctggtcacc ttccctgaca acgcagacat gtggggcctg ggaaatgaaa
      121 gagcgccttg ggacaggggg atttggaaat gtcatccgat ggcacaatca ggaaacaggt
      181 gagcagattg ccatcaagca gtgccggcag gagctcagcc cccggaaccg agagcggtgg
      241 tgcctggaga tccagatcat gagaaggctg acccacccca atgtggtggc tgcccgagat
      301 gtccctgagg ggatgcagaa cttggcgccc aatgacctgc ccctgctggc catggagtac
      361 tgccaaggag gagatctccg gaagtacctg aaccagtttg agaactgctg tggtctgcgg
      421 gaaggtgcca tcctcacctt gctgagtgac attgcctctg cgcttagata ccttcatgaa
      481 aacagaatca tccatcggga tctaaagcca gaaaacatcg tcctgcagca aggagaacag
      541 aggttaatac acaaaattat tgacctagga tatgccaagg agctggatca gggcgaactt
      601 tgcacagaat tcgtggggac cctgcagtac ctggccccag agctactgga gcagcagaag
      661 tacacagtga ccgtcgacta ctggagcttc ggcaccctgg cctttgagtg catcacgggc
      721 ttccggccct tcctccccaa ctggcagccc gtgcagtggc attcaaaagt gcggcagaag
      781 agtgaggtgg acattgttgt tagcgaagac ttgaatggaa cggtgaagtt ttcaagctct
      841 ttaccctacc ccaataatct taacagtgtc ctggctga
//
